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File:IPLab10Candidiasis8.jpg|This is a higher-power photomicrograph of a Candida colony in the kidney. Note the pseudohyphae of the Candida organisms.
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== Study Questions ==
* <spoiler text="What is the significance of seeing yeast and hyphae in these histologic tissue sections?">Candida is the only fungus which grows as:
# a yeast form,
# pseudohyphae, and
# true hyphae with septa.
All three of these forms may be present in the same section of tissue.</spoiler>
* <spoiler text="Who is at risk for developing systemic candidiasis?">Neutropenic patients.
Candida species--especially C. albicans--are part of the normal flora of the skin, mouth, and GI tract, and are the most frequent cause of human fungal infections. These infections vary from superficial lesions in healthy persons to disseminated infections in neutropenic patients.
Severe disseminated candidiasis is associated with neutropenia secondary to chronic granulomatous disease, leukemia, anticancer therapy, or immunosuppression after transplantation.
Candida can be introduced into the bloodstream by intravenous lines, catheters, peritoneal dialysis, cardiac surgery, or intravenous drug abuse.</spoiler>
* <spoiler text="What types of infections does Candida cause in humans?">Candida infections can occur in the oral cavity (thrush), vagina, and in the skin--especially in warm moist areas (i.e., between the fingers and toes and in inguinal creases, inframammary folds, and the anogenital region).
Candida esophagitis can occur with nasogastric tube placement.</spoiler>
{{IPLab 10}}
[[Category: IPLab:Lab 10]]