Cytologically Yours: CoW: 20140227

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Clinical Summary

The patient is a 74 year old female with a history of sarcoma of the right thigh and a new lung mass.

Past Medical History

  • Sarcoma of thigh (3 years prior)
  • Osteoarthritis

Past Surgical History

  • Previous excision of thigh sarcoma.
  • Hysterectomy

Radiology

  • CT showed a right upper lobe low density nodule measuring 3.0 x 2.6 cm which is abutting the pleural surface.

Clinical Plan

The patient was scheduled for an endobronchial ultrasound guided fine needle aspiration biopsy.

Pathology

Cytology


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Final Diagnosis

Cytology

  • Positive for malignancy, favor liposarcoma.


Biopsy

Previous Soft Tissue Biopsy Diagnosis

  • High grade pleomorphic liposarcoma.


Discussion

The diagnosis of pleomorphic liposarcoma on cytology rests on the presence of highly atypical, sometimes multinucleated lipoblasts. The scalloped nucleus is an important diagnostic feature.