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IPLab8HSVEncephalitis12.jpg|This is a photomicrograph of a brain section stained with an antibody against herpes simplex. Even at this magnification, it is easy to pick out cells that are positive for the virus (arrows).
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== Study Questions ==
* <spoiler text="What age groups are susceptible to herpetic encephalitis?">HSV-1 (labialis) produces encephalitis in any age group but is most common in children and young adults. Only about 10% of the patients have a history of prior labial herpes.</spoiler>
* <spoiler text="What type of injury is produced by herpetic encephalitis, what areas of the brain are affected, and what are the most common clinical presenting signs/symptoms?">Encephalitis usually involves the inferior and medial regions of the temporal lobes and the orbital gyri of the frontal lobes. The infection is grossly necrotizing and often hemorrhagic with perivascular inflammatory infiltrates and Cowdry intranuclear viral inclusion bodies in both neurons and glia. The most commonly observed clinical presenting symptoms are alterations in mood, memory, and behavior.</spoiler>
{{IPLab 8}}
[[Category: IPLab:Lab 8]]