User contributions
20 August 2013
File:IPLab6Amyloid9.jpg
This is a gross photograph of kidney from this case. Note the pale yellow material within the cortex (arrows). This is indicative of amyloid within the cortex and the glomeruli. Also note that there are multiple red spots in the cortex. These represent...
File:IPLab6Amyloid8.jpg
This is a photomicrograph of Congo-red-stained liver tissue viewed with partially polarized light. Although not well demonstrated in this image, Congo-red-stained amyloid viewed through polarized light should give off a classic “apple green” birefr...
File:IPLab6Amyloid7.jpg
This is a high-power view of liver tissue stained with Congo red. The orange amyloid material (arrows) is seen clearly between liver parenchymal cells.
File:IPLab6Amyloid6.jpg
This is a low-power photomicrograph of liver tissue stained with Congo red (orange color in slide). Congo red reacts with amyloid and gives it an orange color (arrows).
File:IPLab6Amyloid5.jpg
This is a higher-power photomicrograph showing the amyloid deposits (1) between hepatocytes (2).
File:IPLab6Amyloid4.jpg
This is a low-power photomicrograph of liver tissue from this case. Note the eosinophilic hyaline material (1) present within and between the hepatic tissue (2). There is marked distortion of lobular architecture by the amyloid.
File:IPLab6Amyloid3.jpg
This is a closer view of the cut surface of this liver. The pale waxy material can be seen within the hepatic tissue (arrows).
File:IPLab6Amyloid2.jpg
This is a gross picture of the cut surface of the liver from this case. The liver tissue is firm and has a waxy appearance--although this is difficult to appreciate in an image.
File:IPLab6Amyloid1.jpg
This is a gross picture of liver from this case. Note the pale, swollen appearance of this liver.
File:IPLab6SenileAmyloidosis5.jpg
This is a special stain for amyloid (Luxol PAS) demonstrating the amyloid (1) and fibrosis (2) in the myocardium. The amyloid is darker purple/magenta and tends to be more amorphous. The fibrosis is pink and more fibrillar.
IPLab:Lab 6:Senile Amyloidosis
Created page with "== Images == <gallery heights="250px" widths="250px"> File:IPLab6SenileAmyloidosis1.jpg|This is a gross photograph of section of heart tissue from this case. The tissue was fi..."
File:IPLab6SenileAmyloidosis4.jpg
This is a higher-power photomicrograph of extracellular amyloid (1) and deposition of amyloid in the vessel wall (2).
File:IPLab6SenileAmyloidosis3.jpg
This is a higher-power photomicrograph of the heart tissue from this case. Note the amyloid deposition throughout the myocardium (1) as well as deposition in the wall of the blood vessel (2).
File:IPLab6SenileAmyloidosis2.jpg
This is a low power photomicrograph of the heart tissue from this case. At this magnification the structure looks relatively normal.
File:IPLab6SenileAmyloidosis1.jpg
This is a gross photograph of section of heart tissue from this case. The tissue was firm and had a waxy texture. If you use your imagination you can see pale yellow areas within this tissue which represent the amyloid deposits.
19 August 2013
IPLab:Lab 5:Trisomy 21
Created page with "== Images == <gallery heights="250px" widths="250px"> File:IPLab5Downs1.jpg|This is a photomicrograph of cells obtained by amniocentesis that were stained using FISH. The cell..."
File:IPLab5Downs6.jpg
This is a karyotype of a patient with Turner syndrome (45, X).
File:IPLab5Downs5.jpg
This is a karyotype of a patient with Klinefelter syndrome (47, XXY).
File:IPLab5Downs4.jpg
FISH is also useful in the diagnosis of other genetic disorders. This is an example of FISH staining on another patient using a probe specific for DiGeorge's disease. The arrow shows that there is a deletion on chromosome 22, which is diagnostic for Di...
File:IPLab5Downs3.jpg
Chromosomes from the chromosome spread are lined up to demonstrate the karyotype. In this case there are three copies of chromosome 21, just as noted in the FISH.
File:IPLab5Downs2.jpg
These cells, obtained by amniocentesis, were cultured and then arrested in metaphase. Nuclei from these cells were isolated and stained to demonstrate the banding pattern of each chromosome. This photograph shows a "chromosome spread." Each chromosome ...
File:IPLab5Downs1.jpg
This is a photomicrograph of cells obtained by amniocentesis that were stained using FISH. The cell in panel 1 was stained with markers specific for the X and Y-chromosomes. The cell in panel 2 was stained with a marker specific for chromosome 18. The ...
File:IPLab6GravesDisease7.jpg
Closer view of cut surface of the thyroid with nodular goiter. Note the multilobular appearance of the tissue.
IPLab:Lab 6:Graves Disease
Created page with "== Images == <gallery heights="250px" widths="250px"> File:IPLab6GravesDisease1.jpg|This is a photograph of the thyroid from this case. Note that the gland is enlarged and is ..."
File:IPLab6GravesDisease6.jpg
This is a gross photograph of a thyroid from a case of nodular goiter.
File:IPLab6GravesDisease5.jpg
This is a high-power photomicrograph of thyroid. Note the papillary projections and the moth-eaten appearance of the colloid. This appearance indicates active absorption of the colloid to form thyroglobulin.
File:IPLab6GravesDisease4.jpg
This is a high-power photomicrograph of thyroid. Note the cellularity of the tissue with marked infolding of the epithelial tissue.
File:IPLab6GravesDisease3.jpg
This is a higher-power photomicrograph of thyroid. The tissue is very cellular and there is little colloid.
File:IPLab6GravesDisease2.jpg
This is a low-power photomicrograph of thyroid tissue from this case. The tissue is very cellular with very little colloid.
File:IPLab6GravesDisease1.jpg
This is a photograph of the thyroid from this case. Note that the gland is enlarged and is dark red.
IPLab:Lab 6:Rheumatoid Arthritis
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+10
IPLab:Lab 6:Rheumatoid Arthritis
Created page with "== Images == <gallery heights="250px" widths="250px"> File:IPLab6RA1.jpg|This is a gross photograph of the patient's hands at autopsy. Note the swollen joints and the deformin..."
File:IPLab6RA10.jpg
This is a high-power photomicrograph of another region with macrophages (right), fibrocytes (left), and occasional lymphocytes throughout the lesion.
File:IPLab6RA9.jpg
This is a high-power photomicrograph of the mononuclear cells which surround the central area of necrosis. The focal accumulations of fibrinoid material are clearly visible. Lymphocytes are present in the extreme right of this image.
File:IPLab6RA8.jpg
This higher-power photomicrograph of the tissue illustrates the palisading nuclei of the monocytes which are located around the periphery of the central necrotic region (1).
File:IPLab6RA7.jpg
This higher-power photomicrograph of the subcutaneous nodule again demonstrates the necrotic center and peripheral rim of macrophages, fibrocytes, and occasional lymphocytes. There are focal accumulations of hyaline material (fibrinoid material) within...
File:IPLab6RA6.jpg
This higher-power photomicrograph of the subcutaneous nodule shows a granulomatous lesion with a necrotic center and a peripheral rim of macrophages, fibrocytes, and occasional lymphocytes. In the necrotic center of the granuloma there is some minerali...
File:IPLab6RA5.jpg
This is a low-power photomicrograph of the subcutaneous nodule from this patient.
File:IPLab6RA4.jpg
This is a gross photograph of the foot from this same patient. Note the subcutaneous nodule on the medial aspect of the foot (arrow).
File:IPLab6RA3.jpg
This is a high-power photomicrograph of the joint capsule with another granuloma surrounding a central area of fibrinoid necrosis (arrow).
File:IPLab6RA2.jpg
This is a medium-power photomicrograph of the joint capsule surrounding the metacarpal joints. Note the thickening of the capsule and the focal accumulation of inflammatory cells surrounding a central area of fibrinoid necrosis (arrow).
File:IPLab6RA1.jpg
This is a gross photograph of the patient's hands at autopsy. Note the swollen joints and the deforming arthritis.
IPLab:Lab 13:Additional Resources
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+42
IPLab:Lab 13:Additional Resources
Created page with "== Images == * [http://library.med.utah.edu/WebPath/PEDHTML/PEDIDX.html WebPath: Perinatal-Pediatric] == Quizzes == * [http://library.med.utah.edu/WebPath/EXAM/MULTGEN/per1fr..."
IPLab:Lab 13:Objectives
Created page with "* Know the basic age groupings and what types of injuries or diseases are most common in each of these age groups. * Describe the usual causes, the pathogenesis, the treatment..."
Template:IPLab 13
Created page with "{{Navbox |name = IPLab 13 |title = IPLab |bodyclass = hlist Lab 13: Diseases of Infancy |group1 = Lab 13: Diseases of Infancy |list1 = * ..."
Category:IPLab:Lab 13
Created page with "Category: IPLab"
IPLab:Lab 13
Created page with "* Objectives * Spine: Myelomeningocele * Liver: Biliary Atresia * IPLab:Lab 13..."
IPLab:Lab 12:Additional Resources
Created page with "== Images == * [http://library.med.utah.edu/WebPath/FORHTML/FORIDX.html WebPath: Forensic Pathology] == Quizzes == * [http://library.med.utah.edu/WebPath/EXAM/MULTGEN/forfrm...."
IPLab:Lab 12:Objectives
Created page with "* Be able to describe the mechanisms of action and the detrimental effects of the common types of environmental pollutants, chemicals, and drugs. * Define anthracosis, silicos..."