IPLab:Lab 4:Chronic Passive Congestion

Images

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  This is a gross photograph of a liver demonstrating chronic passive congestion. Note the accentuation of the centrilobular pattern evidenced by the dark-brown-staining areas in this tissue.

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  This is a closer view of a cut section of liver demonstrating the pattern of chronic passive congestion. The central vein regions are red and the surrounding hepatic tissue is pale tan-brown.

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  This low-power photomicrograph of liver demonstrates a slightly visible pattern of centrilobular congestion at this magnification.

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  This is a higher-power photomicrograph of liver demonstrating an accentuated lobular pattern with a dark red stain surrounding the central veins in the liver lobules (arrows).

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  This higher-power photomicrograph of the liver lobules shows congestion and red blood cell accumulation in the sinusoidal spaces around the central vein. Note that around the portal triads (arrows) the liver cells are quite normal and there is no evidence of congestion.

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  This is a high-power photomicrograph of the central vein illustrating congestion and some loss of liver parenchymal cells. A mild increase in connective tissue around the central vein is evident in this section.

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  This is a high-power photomicrograph of liver with several macrophages that are distended with a brown pigment (arrow). These resident macrophages (Kupffer cells) are part of the reticuloendothelial system and normally line the sinusoidal spaces in the liver where they phagocytose the RBCs that pool, and eventually die, in the central vein region.

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  This is a gross photograph of a nutmeg. You can see from the appearance of the cut surface of the nutmeg (arrow) why chronic passive congestion of the liver is sometimes referred to as "nutmeg liver."

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  This is a gross photograph of the cut surface of a liver with chronic passive congestion (left) compared to the cut surface of a nutmeg (right).