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(newest | oldest) View (newer 50 | older 50) (20 | 50 | 100 | 250 | 500)- 14:53, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Hemochromatosis3.jpg (This is a low-power micrograph of liver from this patient. Note the nodularity of the tissue (arrows).)
- 14:53, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Hemochromatosis2.jpg (This is a gross photograph of a cut section of liver from this case of hemochromatosis. Note that the liver is dark brown. Although hard to appreciate in a photograph, the tissue is also firm (cirrhotic).)
- 14:52, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Hemochromatosis1.jpg (This is a gross photograph of liver (1) and pancreas (2) from this case of hemochromatosis. Note that both of these organs have a dark brown coloration.)
- 18:29, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab5Downs6.jpg (This is a karyotype of a patient with Turner syndrome (45, X).)
- 18:28, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab5Downs5.jpg (This is a karyotype of a patient with Klinefelter syndrome (47, XXY).)
- 18:28, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Antitrypsin12.jpg (This is a high-power photomicrograph of liver stained with periodic-acid Schiff's (PAS) stain. This demonstrates the PAS-positive granules of defective alpha 1-antitrypsin that accumulate in the Golgi of hepatocytes (arrows).)
- 18:28, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab5Downs4.jpg (FISH is also useful in the diagnosis of other genetic disorders. This is an example of FISH staining on another patient using a probe specific for DiGeorge's disease. The arrow shows that there is a deletion on chromosome 22, which is diagnostic for Di...)
- 18:28, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Antitrypsin11.jpg (This is a higher-power photomicrograph of a trichrome-stained section of liver. This section demonstrates the fibrosis (blue material) and the fatty change (arrows).)
- 18:28, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab5Downs3.jpg (Chromosomes from the chromosome spread are lined up to demonstrate the karyotype. In this case there are three copies of chromosome 21, just as noted in the FISH.)
- 18:27, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Antitrypsin10.jpg (This is a low-power photomicrograph of a trichrome-stained section of liver. There is bridging fibrosis (blue material) between portal regions.)
- 18:27, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab5Downs2.jpg (These cells, obtained by amniocentesis, were cultured and then arrested in metaphase. Nuclei from these cells were isolated and stained to demonstrate the banding pattern of each chromosome. This photograph shows a "chromosome spread." Each chromosome ...)
- 18:27, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab5Downs1.jpg (This is a photomicrograph of cells obtained by amniocentesis that were stained using FISH. The cell in panel 1 was stained with markers specific for the X and Y-chromosomes. The cell in panel 2 was stained with a marker specific for chromosome 18. The ...)
- 18:27, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Antitrypsin9.jpg (This is a low-power photomicrograph of an H&E-stained section of liver. There are increased numbers of inflammatory cells in the periportal region (arrow) and the central vein areas are pale.)
- 18:26, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Antitrypsin8.jpg (This is a closer view of the cut section of liver from this case. There is a definite micronodular pattern to the liver parenchyma.)
- 18:26, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Antitrypsin7.jpg (This is a gross photograph of the cut section of liver from this case. In this view the liver looks smaller than normal and there is a definite micronodular appearance.)
- 18:25, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Antitrypsin6.jpg (This is a gross photograph of the liver from this case. The capsule is somewhat thickened and the surface is slightly roughened, though it is difficult to appreciate the nodularity of the liver.)
- 18:23, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6GravesDisease7.jpg (Closer view of cut surface of the thyroid with nodular goiter. Note the multilobular appearance of the tissue.)
- 18:23, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6GravesDisease6.jpg (This is a gross photograph of a thyroid from a case of nodular goiter.)
- 18:23, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6GravesDisease5.jpg (This is a high-power photomicrograph of thyroid. Note the papillary projections and the moth-eaten appearance of the colloid. This appearance indicates active absorption of the colloid to form thyroglobulin.)
- 18:22, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6GravesDisease4.jpg (This is a high-power photomicrograph of thyroid. Note the cellularity of the tissue with marked infolding of the epithelial tissue.)
- 18:22, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6GravesDisease3.jpg (This is a higher-power photomicrograph of thyroid. The tissue is very cellular and there is little colloid.)
- 18:22, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6GravesDisease2.jpg (This is a low-power photomicrograph of thyroid tissue from this case. The tissue is very cellular with very little colloid.)
- 18:21, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6GravesDisease1.jpg (This is a photograph of the thyroid from this case. Note that the gland is enlarged and is dark red.)
- 18:13, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Antitrypsin3.jpg (This is a gross photograph of the bronchi and lungs. Note the hemorrhage in the bronchi and in the lung parenchyma.)
- 18:09, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6RA10.jpg (This is a high-power photomicrograph of another region with macrophages (right), fibrocytes (left), and occasional lymphocytes throughout the lesion.)
- 18:09, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Antitrypsin5.jpg (This is a low-power photomicrograph from an area of the lung without significant hemorrhage. The enlarged, emphysematous air spaces are easily appreciated.)
- 18:08, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6RA9.jpg (This is a high-power photomicrograph of the mononuclear cells which surround the central area of necrosis. The focal accumulations of fibrinoid material are clearly visible. Lymphocytes are present in the extreme right of this image.)
- 18:08, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6RA8.jpg (This higher-power photomicrograph of the tissue illustrates the palisading nuclei of the monocytes which are located around the periphery of the central necrotic region (1).)
- 18:07, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6RA7.jpg (This higher-power photomicrograph of the subcutaneous nodule again demonstrates the necrotic center and peripheral rim of macrophages, fibrocytes, and occasional lymphocytes. There are focal accumulations of hyaline material (fibrinoid material) within...)
- 18:07, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Antitrypsin4.jpg (This is a gross photograph of the bronchi and lungs. Note the hemorrhage in the bronchi and in the lung parenchyma.)
- 18:07, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6RA6.jpg (This higher-power photomicrograph of the subcutaneous nodule shows a granulomatous lesion with a necrotic center and a peripheral rim of macrophages, fibrocytes, and occasional lymphocytes. In the necrotic center of the granuloma there is some minerali...)
- 18:07, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Antitrypsin2.jpg (This is a gross photograph of the cut sections of lung from this case. The lung parenchyma is markedly hemorrhagic and consolidated. Again the hemorrhage makes it difficult to appreciate the emphysematous changes.)
- 18:07, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6RA5.jpg (This is a low-power photomicrograph of the subcutaneous nodule from this patient.)
- 18:06, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Antitrypsin1.jpg (This is a gross photograph of the lungs from this case. The rough friable material on the surface of the lung (arrows) is fibrinous exudate and fibrous tissue. This reaction on the surface of the lung is due to the recent surgery. The emphysematous cha...)
- 18:06, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6RA4.jpg (This is a gross photograph of the foot from this same patient. Note the subcutaneous nodule on the medial aspect of the foot (arrow).)
- 18:06, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6RA3.jpg (This is a high-power photomicrograph of the joint capsule with another granuloma surrounding a central area of fibrinoid necrosis (arrow).)
- 18:06, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6RA2.jpg (This is a medium-power photomicrograph of the joint capsule surrounding the metacarpal joints. Note the thickening of the capsule and the focal accumulation of inflammatory cells surrounding a central area of fibrinoid necrosis (arrow).)
- 18:05, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6RA1.jpg (This is a gross photograph of the patient's hands at autopsy. Note the swollen joints and the deforming arthritis.)
- 17:54, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5PolycysticKidney11.jpg (This is a higher-power photomicrograph of liver cyst. These cystic structures are lined by biliary epithelium.)
- 17:54, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5PolycysticKidney10.jpg (This is another photomicrograph of liver demonstrating the histologic appearance of these cysts. These cystic structures are associated with the biliary tree.)
- 17:53, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5PolycysticKidney9.jpg (This photomicrograph of liver demonstrates the histologic appearance of these cysts.)
- 17:53, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5PolycysticKidney8.jpg (This is a gross photograph of the liver from this patient. Multiple cysts can be seen on the surface of this liver (arrows).)
- 17:52, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5PolycysticKidney7.jpg (This high-power photomicrograph shows abnormal glomeruli (arrows) and some tubules.)
- 17:52, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5PolycysticKidney6.jpg (This is a higher-power photomicrograph of polycystic kidney showing the edge of a large cyst (1). In this section there are numerous tubules and dilated collecting ducts (2) that are filled with the same red proteinaceous material as the larger cysts.)
- 17:51, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5PolycysticKidney5.jpg (This is another low-power photomicrograph of an H&E-stained section from this polycystic kidney. Again note the large cystic structures (arrows)and the fibrous connective tissue throughout this section.)
- 17:51, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5PolycysticKidney4.jpg (This is a low-power photomicrograph of an H&E-stained section from this polycystic kidney. Note the large cystic structures (1), the few residual glomeruli (2), and the fibrous connective tissue throughout this section.)
- 17:49, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5PolycysticKidney3.jpg (This is a gross photograph of a cut section from one of these polycystic kidneys. Note that the renal parenchyma is almost completely replaced by cystic structures.)
- 17:44, 19 August 2013 Peter Anderson (talk | contribs) deleted page File:IPLab5PolycysticKidney3.jpg
- 17:43, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5PolycysticKidney3.jpg (This is a gross photograph of a cut section from one of these polycystic kidneys. Note that the renal parenchyma is almost completely replaced by cystic structures.)
- 17:40, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5PolycysticKidney2.jpg (This is a gross photograph of the kidneys from this case. Note that both kidneys contain multiple large cysts (arrows).)