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IPLab:Lab 2:Fatty Change and Cirrhosis

3 bytes added, 20:56, 19 June 2020
Images
File:IPLab2FattyChange1.jpg|This gross photograph of liver tissue illustrates the yellowish color of the liver parenchyma. The yellow color indicates high fat content in this tissue. Compare this with the normal dark red color of liver.
File:IPLab2FattyChange2.jpg|This low-power photomicrograph of liver illustrates a very pale-staining section with a uniform appearance throughout the section.
File:IPLab2FattyChange3IPLab2FattyChange3b.jpg|Another low-power photomicrograph illustrates again the pale, washed-out appearance of this tissue. Notice the numerous holes throughout the tissue. There are accumulations of inflammatory cells (arrow) around portal tracts.File:IPLab2FattyChange4IPLab2FattyChange4b.jpg|A higher-power photomicrograph illustrates more clearly the inflammatory cells (arrow) around the portal areas.File:IPLab2FattyChange5IPLab2FattyChange5b.jpg|High power view of hepatocytes with lipid vacuoles. In many cases the nucleus is displaced to the periphery of the cell and the entire cytoplasm is taken up by the giant lipid vacuole.
File:IPLab2FattyChange8.jpg|An oil red O stain for fat was performed on a frozen section of this liver tissue. The red droplets represent fat in the tissue which is typical of fatty degeneration in the liver. By using frozen sections the tissues do not have to be dehydrated through alcohol solutions and thus the fat does not get washed out.
File:IPLab2FattyChange9.jpg|This photomicrograph of the liver is from another patient with a history of alcohol use. There are some clear vacuoles indicating fat droplets (1) and there are numerous red-staining granular deposits within the cytoplasm of hepatocytes (3)this is alcoholic hyalin. Alcoholic hyalin is easily distinguished from red blood cells (2) that are also present in this section.