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→Clinical Summary
This 45-year-old white female with a history of psychiatric illness sustained self-inflicted third degree burns over 49% of her body surface. After initially doing well under treatment, she developed severe respiratory distress and became comatose. Antemortem blood cultures were positive for Pseudomonas aeruginosa.
== Images ==
IPLab9BacterialMeningitis8.jpg|This photomicrograph of brain tissue demonstrates diffuse edema.
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== Virtual Microscopy ==
<peir-vm>IPLab9BacterialMeningitis</peir-vm>
== Study Questions ==
* <spoiler text="What organism caused meningitis in this case and why?">Burn patients are at high risk for developing Pseudomonas infections. In this case, the patient was debilitated due to the extensive severe burn and developed a Pseudomonas septicemia which then led to the Pseudomonas meningitis.</spoiler>
* <spoiler text="Why is there fibrin in these lesions?">Because of the acute inflammatory reaction, there is extravasation of fibrin as well as the recruitment of neutrophils.</spoiler>
== Additional Resources ==
=== Reference ===
* [http://emedicine.medscape.com/article/961497-overview eMedicine Medical Library: Pediatric Bacterial Meningitis]
* [http://emedicine.medscape.com/article/232915-overview eMedicine Medical Library: Meningitis]
* [http://emedicine.medscape.com/article/1278244-overview eMedicine Medical Library: Thermal Burns]
* [http://emedicine.medscape.com/article/226748-overview eMedicine Medical Library: Pseudomonas aeruginosa Infections]
* [http://www.merckmanuals.com/professional/neurologic_disorders/meningitis/acute_bacterial_meningitis.html Merck Manual: Acute Bacterial Meningitis]
* [http://www.merckmanuals.com/professional/injuries_poisoning/burns/burns.html Merck Manual: Burns]
=== Journal Articles ===
* Grände PO, Myhre EB, Nordström CH, Schliamser S. [http://www.ncbi.nlm.nih.gov/pubmed/11939916 Treatment of intracranial hypertension and aspects on lumbar dural puncture in severe bacterial meningitis]. ''Acta Anaesthesiol Scand'' 2002 Mar;46(3):264-70.
=== Images ===
* [{{SERVER}}/library/index.php?/tags/403-meningitis PEIR Digital Library: Meningitis Images]
* [http://library.med.utah.edu/WebPath/CNSHTML/CNSIDX.html#6 WebPath: CNS Infections]
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[[Category: IPLab:Lab 9]]