IPLab:Lab 9:Bacterial Meningitis - Revision history

Peter Anderson: /* Clinical Summary */

2020-07-09T21:42:50Z

‎Clinical Summary

Peter Anderson: /* Autopsy Findings */

2020-07-09T21:42:35Z

‎Autopsy Findings

Seung Park at 16:31, 3 January 2014

2014-01-03T16:31:38Z

Seung Park: /* Images */

2013-08-30T01:43:28Z

‎Images

Seung Park at 02:01, 24 August 2013

2013-08-24T02:01:17Z

Seung Park at 04:23, 23 August 2013

2013-08-23T04:23:22Z

Seung Park at 15:54, 21 August 2013

2013-08-21T15:54:42Z

Seung Park at 14:37, 21 August 2013

2013-08-21T14:37:08Z

Seung Park: Created page with "== Images == IPLab9BacterialMeningitis1.jpg|This gross photograph of the autopsy specimen from this case demonstrates the purulent exu..."

2013-08-21T03:47:57Z

Created page with "== Images == <gallery heights="250px" widths="250px"> IPLab9BacterialMeningitis1.jpg|This gross photograph of the autopsy specimen from this case demonstrates the purulent exu..."

New page

== Images ==
<gallery heights="250px" widths="250px">
IPLab9BacterialMeningitis1.jpg|This gross photograph of the autopsy specimen from this case demonstrates the purulent exudate (arrows) in the leptomeninges.
IPLab9BacterialMeningitis2.jpg|This is a low-power photomicrograph of brain section. Note the exudate (1) in the meninges and congestion of the vessels (2) in the leptomeninges.
IPLab9BacterialMeningitis3.jpg|This is a higher-power view of a congested blood vessel. Inflammatory exudate is present within the vessel and throughout the leptomeninges.
IPLab9BacterialMeningitis4.jpg|This higher-power photomicrograph of a sulcus shows the congested vessels and the inflammatory exudate in the leptomeninges.
IPLab9BacterialMeningitis5.jpg|This is a higher-power photomicrograph of inflammatory exudate in a sulcus. The majority of cells in this exudate are neutrophils. There is also abundant fibrin (arrows) and red blood cells are present in the congested vessels.
IPLab9BacterialMeningitis6.jpg|This is a high-power photomicrograph of a blood vessel from the previous image. The vessel is surrounded by neutrophils (arrows).
IPLab9BacterialMeningitis7.jpg|This is a high-power photomicrograph of exudate from the leptomeninges which has been Gram-stained. Note the Gram-negative bacteria (arrows) throughout this section.
IPLab9BacterialMeningitis8.jpg|This photomicrograph of brain tissue demonstrates diffuse edema.
</gallery>

{{IPLab 9}}

[[Category: IPLab:Lab 9]]

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 == Clinical Summary ==
 This 45-year-old white female with a history of psychiatric illness sustained self-inflicted third degree burns over 49% of her body surface. After initially doing well under treatment, she developed severe respiratory distress and became comatose. Antemortem blood cultures were positive for Pseudomonas aeruginosa.
 == Images ==

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 == Clinical Summary ==
 This 45-year-old white female with a history of psychiatric illness sustained self-inflicted third degree burns over 49% of her body surface. After initially doing well under treatment, she developed severe respiratory distress and became comatose. Antemortem blood cultures were positive for Pseudomonas aeruginosa.
 == Images ==

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 === Images ===
-* [http://peir.path.uab.edu/library/index.php?/tags/403-meningitis PEIR Digital Library: Meningitis Images]
+* [{{SERVER}}/library/index.php?/tags/403-meningitis PEIR Digital Library: Meningitis Images]
 * [http://library.med.utah.edu/WebPath/CNSHTML/CNSIDX.html#6 WebPath: CNS Infections]

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 == Additional Resources ==
 === Reference ===
+* [http://emedicine.medscape.com/article/961497-overview eMedicine Medical Library: Pediatric Bacterial Meningitis]
 === Journal Articles ===
+* Grände PO, Myhre EB, Nordström CH, Schliamser S. [http://www.ncbi.nlm.nih.gov/pubmed/11939916 Treatment of intracranial hypertension and aspects on lumbar dural puncture in severe bacterial meningitis].  ''Acta Anaesthesiol Scand'' 2002 Mar;46(3):264-70.
 === Images ===
+* [http://peir.path.uab.edu/library/index.php?/tags/403-meningitis PEIR Digital Library: Meningitis Images]
+* [http://library.med.utah.edu/WebPath/CNSHTML/CNSIDX.html#6 WebPath: CNS Infections]
 {{IPLab 9}}
 [[Category: IPLab:Lab 9]]

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 * <spoiler text="What organism caused meningitis in this case and why?">Burn patients are at high risk for developing Pseudomonas infections. In this case, the patient was debilitated due to the extensive severe burn and developed a Pseudomonas septicemia which then led to the Pseudomonas meningitis.</spoiler>
 * <spoiler text="Why is there fibrin in these lesions?">Because of the acute inflammatory reaction, there is extravasation of fibrin as well as the recruitment of neutrophils.</spoiler>
 {{IPLab 9}}
 [[Category: IPLab:Lab 9]]

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 IPLab9BacterialMeningitis8.jpg|This photomicrograph of brain tissue demonstrates diffuse edema.
 </gallery>
 == Study Questions ==

← Older revision		Revision as of 14:37, 21 August 2013
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		+	== Clinical Summary ==
		+	This 45-year-old white female with a history of psychiatric illness sustained self-inflicted third degree burns over 49% of her body surface. After initially doing well under treatment, she developed severe respiratory distress and became comatose. Antemortem blood cultures were positive for Pseudomonas aeruginosa.
		+
		+	== Autopsy Findings ==
		+	At autopsy the principal findings were in the lungs and brain. Bronchopneumonia was present in all lobes of both lungs. The brain weighed 1450 grams and the leptomeninges contained a thick yellow purulent exudate most prominent over the frontoparietal areas and at the base of the brain.
		+
	== Images ==		== Images ==
	<gallery heights="250px" widths="250px">		<gallery heights="250px" widths="250px">