IPLab:Lab 9:ARF - Revision history

Peter Anderson: /* Clinical Summary */

2020-07-09T21:44:25Z

Clinical Summary

← Older revision		Revision as of 21:44, 9 July 2020
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	== Clinical Summary ==		== Clinical Summary ==
	This 21-year-old black male with sickle cell anemia had recurrent attacks of acute rheumatic fever beginning at age 14. Mitral insufficiency and stenosis were present by age 16. On prophylactic antibiotics, the patient had no evidence of recurrence until three weeks before his final admission, when an upper respiratory infection developed. A few weeks later he developed acute migratory polyarthritis. This was associated with rapid deterioration of cardiac function and death.		This 21-year-old black male with sickle cell anemia had recurrent attacks of acute rheumatic fever beginning at age 14. Mitral insufficiency and stenosis were present by age 16. On prophylactic antibiotics, the patient had no evidence of recurrence until three weeks before his final admission, when an upper respiratory infection developed. A few weeks later he developed acute migratory polyarthritis. This was associated with rapid deterioration of cardiac function and death.

			At autopsy, the heart was enlarged--weighing 675 grams--especially the left atrium. Both the aortic and mitral valves showed fibrosis as well as the fresh, tiny verrucae characteristic of acute rheumatic fever.

	== Images ==		== Images ==

2020-07-09T21:44:11Z

Autopsy Findings

← Older revision		Revision as of 21:44, 9 July 2020
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	== Clinical Summary ==		== Clinical Summary ==
	This 21-year-old black male with sickle cell anemia had recurrent attacks of acute rheumatic fever beginning at age 14. Mitral insufficiency and stenosis were present by age 16. On prophylactic antibiotics, the patient had no evidence of recurrence until three weeks before his final admission, when an upper respiratory infection developed. A few weeks later he developed acute migratory polyarthritis. This was associated with rapid deterioration of cardiac function and death.		This 21-year-old black male with sickle cell anemia had recurrent attacks of acute rheumatic fever beginning at age 14. Mitral insufficiency and stenosis were present by age 16. On prophylactic antibiotics, the patient had no evidence of recurrence until three weeks before his final admission, when an upper respiratory infection developed. A few weeks later he developed acute migratory polyarthritis. This was associated with rapid deterioration of cardiac function and death.

	~~== Autopsy Findings ==~~
	At autopsy, the heart was enlarged--weighing 675 grams--especially the left atrium. Both the aortic and mitral valves showed fibrosis as well as the fresh, tiny verrucae characteristic of acute rheumatic fever.

	== Images ==		== Images ==

2016-11-29T14:52:41Z

Journal Articles

← Older revision		Revision as of 14:52, 29 November 2016
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	=== Journal Articles ===		=== Journal Articles ===
	* ~~Wong S, French R, Bolson E, McDonald J, Legget M, Sheehan F~~. [http://~~www~~.~~ncbi~~.~~nlm~~.~~nih~~.~~gov/pubmed/11685179 Morphologic features~~ of the ~~rheumatic mitral regurgitant valve by three-dimensional echocardiography~~]. ''~~Am Heart J~~'' ~~2001 Nov~~;~~142(5)~~:~~897~~-~~907~~.		* American Heart Association Committee on Rheumatic Fever. [http://dx.doi.org/10.1161/CIR.0000000000000205 Revision of the Jones Criteria for the Diagnosis of Acute Rheumatic Fever in the Era of Doppler Echocardiography]. ''Circulation'' 2015 April 23; 131:1806-1818.

	=== Images ===		=== Images ===

2014-01-03T16:32:00Z

← Older revision		Revision as of 16:32, 3 January 2014
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	File:IPLab9ARF6.jpg\|This high-power photomicrograph of myocardium shows the cellular detail of another Aschoff body. In this case there appears to be a multinucleated Aschoff giant cell (arrow).		File:IPLab9ARF6.jpg\|This high-power photomicrograph of myocardium shows the cellular detail of another Aschoff body. In this case there appears to be a multinucleated Aschoff giant cell (arrow).
	</gallery>		</gallery>

			== Virtual Microscopy ==
			<peir-vm>IPLab9ARF</peir-vm>

	== Study Questions ==		== Study Questions ==

2013-08-30T01:43:51Z

Images

← Older revision		Revision as of 01:43, 30 August 2013
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	=== Images ===		=== Images ===
	* [~~http://peir.path.uab.edu~~/library/index.php?/tags/2153-streptococcus PEIR Digital Library: Streptococcus Images]		* [{{SERVER}}/library/index.php?/tags/2153-streptococcus PEIR Digital Library: Streptococcus Images]
	* [http://library.med.utah.edu/WebPath/CVHTML/CVIDX.html#8 Webpath: Myocarditis]		* [http://library.med.utah.edu/WebPath/CVHTML/CVIDX.html#8 Webpath: Myocarditis]

2013-08-24T02:09:54Z

Related IPLab Cases

← Older revision		Revision as of 02:09, 24 August 2013
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	* [http://peir.path.uab.edu/library/index.php?/tags/2153-streptococcus PEIR Digital Library: Streptococcus Images]		* [http://peir.path.uab.edu/library/index.php?/tags/2153-streptococcus PEIR Digital Library: Streptococcus Images]
	* [http://library.med.utah.edu/WebPath/CVHTML/CVIDX.html#8 Webpath: Myocarditis]		* [http://library.med.utah.edu/WebPath/CVHTML/CVIDX.html#8 Webpath: Myocarditis]

	~~== Related IPLab Cases ==~~


	{{IPLab 9}}		{{IPLab 9}}

	[[Category: IPLab:Lab 9]]		[[Category: IPLab:Lab 9]]

2013-08-24T02:09:44Z

Images

← Older revision		Revision as of 02:09, 24 August 2013
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	=== Images ===		=== Images ===
			* [http://peir.path.uab.edu/library/index.php?/tags/2153-streptococcus PEIR Digital Library: Streptococcus Images]
			* [http://library.med.utah.edu/WebPath/CVHTML/CVIDX.html#8 Webpath: Myocarditis]

	== Related IPLab Cases ==		== Related IPLab Cases ==

2013-08-24T02:08:16Z

Journal Articles

← Older revision		Revision as of 02:08, 24 August 2013
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	=== Journal Articles ===		=== Journal Articles ===
			* Wong S, French R, Bolson E, McDonald J, Legget M, Sheehan F. [http://www.ncbi.nlm.nih.gov/pubmed/11685179 Morphologic features of the rheumatic mitral regurgitant valve by three-dimensional echocardiography]. ''Am Heart J'' 2001 Nov;142(5):897-907.

	=== Images ===		=== Images ===

2013-08-24T02:07:35Z

Reference

← Older revision		Revision as of 02:07, 24 August 2013
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	== Additional Resources ==		== Additional Resources ==
	=== Reference ===		=== Reference ===
			* [http://emedicine.medscape.com/article/236582-overview eMedicine Medical Library: Rheumatic Fever]
			* [http://emedicine.medscape.com/article/808945-overview eMedicine Medical Library: Rheumatic Fever in Emergency Medicine]
			* [http://emedicine.medscape.com/article/333103-overview eMedicine Medical Library: Acute Rheumatic Fever]
			* [http://www.merckmanuals.com/professional/pediatrics/rheumatic_fever/rheumatic_fever.html Merck Manual: Rheumatic Fever]

	=== Journal Articles ===		=== Journal Articles ===

2013-08-23T04:23:39Z

← Older revision		Revision as of 04:23, 23 August 2013
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	This patient has acute ramifications of rheumatic fever (acute valve lesions and Aschoff bodies) but there are also a number of old lesions in the heart suggesting that this patient has had numerous bouts of rheumatic fever over the course of many years.</spoiler>		This patient has acute ramifications of rheumatic fever (acute valve lesions and Aschoff bodies) but there are also a number of old lesions in the heart suggesting that this patient has had numerous bouts of rheumatic fever over the course of many years.</spoiler>

			== Additional Resources ==
			=== Reference ===


			=== Journal Articles ===


			=== Images ===


			== Related IPLab Cases ==


	{{IPLab 9}}		{{IPLab 9}}

	[[Category: IPLab:Lab 9]]		[[Category: IPLab:Lab 9]]