IPLab:Lab 7:Malignant Melanoma - Revision history

Peter Anderson: /* Images */

2020-07-09T02:14:27Z

Images

← Older revision		Revision as of 21:14, 8 July 2020
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	File:IPLab7Melanoma1.jpg\|This is a gross photograph of skin with melanoma. Note the black pigment, multiple satellite nodules, and focal ulceration. Some of the satellite nodules affect the nipple.		File:IPLab7Melanoma1.jpg\|This is a gross photograph of skin with melanoma. Note the black pigment, multiple satellite nodules, and focal ulceration. Some of the satellite nodules affect the nipple.
	File:IPLab7Melanoma2.jpg\|This is a gross photograph of lymph nodes almost entirely replaced by black pigment (melanin).		File:IPLab7Melanoma2.jpg\|This is a gross photograph of lymph nodes almost entirely replaced by black pigment (melanin).
	File:~~IPLab7Melanoma3~~.jpg\|This is a low-power photomicrograph of lymph node that is almost completely replaced/filled with tumor. This lymph node has a capsule (1) and some remaining lymphocytes (2) but the remainder of the node is replaced by tumor cells.		File:IPLab7Melanoma3b.jpg\|This is a low-power photomicrograph of lymph node that is almost completely replaced/filled with tumor. This lymph node has a capsule (1) and some remaining lymphocytes (2) but the remainder of the node is replaced by tumor cells.
	File:~~IPLab7Melanoma4~~.jpg\|This higher-power photomicrograph shows the remaining portion of lymph node (arrow). The rest of the lymph node is invaded by a neoplasm composed of cells with lighter eosinophilic cytoplasm and pigment.		File:IPLab7Melanoma4b.jpg\|This higher-power photomicrograph shows the remaining portion of lymph node (arrow). The rest of the lymph node is invaded by a neoplasm composed of cells with lighter eosinophilic cytoplasm and pigment.
	File:~~IPLab7Melanoma5~~.jpg\|This is a higher-magnification showing the abundant extracellular melanin (arrows) surrounding the tumor cells. This section of neoplasm shows the numerous cells with abundant cytoplasm and brown pigment within the cytoplasm of some of these cells.		File:IPLab7Melanoma5b.jpg\|This is a higher-magnification showing the abundant extracellular melanin (arrows) surrounding the tumor cells. This section of neoplasm shows the numerous cells with abundant cytoplasm and brown pigment within the cytoplasm of some of these cells.
	File:~~IPLab7Melanoma6~~.jpg\|This is a higher magnification showing the abundant extracellular melanin surrounding the tumor cells (brown pigment).		File:IPLab7Melanoma6b.jpg\|This is a higher magnification showing the abundant extracellular melanin surrounding the tumor cells (brown pigment).
	File:~~IPLab7Melanoma7~~.jpg\|This is a high-power photomicrograph of the main tumor mass with the cells growing as poorly formed nests and sheets of cells. There is little if any pigment in this section.		File:IPLab7Melanoma7b.jpg\|This is a high-power photomicrograph of the main tumor mass with the cells growing as poorly formed nests and sheets of cells. There is little if any pigment in this section.
	File:IPLab7Melanoma8.jpg\|This is a high-power photomicrograph of the main tumor mass showing the cellular details. The individual melanoma cells contain large nuclei with irregular contours having chromatin clumped at the periphery of the nuclear membrane and prominent red (eosinophilic) nucleoli.		File:IPLab7Melanoma8.jpg\|This is a high-power photomicrograph of the main tumor mass showing the cellular details. The individual melanoma cells contain large nuclei with irregular contours having chromatin clumped at the periphery of the nuclear membrane and prominent red (eosinophilic) nucleoli.
	</gallery>		</gallery>

Peter Anderson: /* Journal Articles */

2015-11-12T14:18:02Z

Journal Articles

← Older revision		Revision as of 09:18, 12 November 2015
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	=== Journal Articles ===		=== Journal Articles ===
	* Banerjee SS, Harris M. [http://www.ncbi.nlm.nih.gov/pubmed/10792480 Morphological and immunophenotypic variations in malignant melanoma]. ''Histopathology'' 2000 May;36(5):387-402.		* Banerjee SS, Harris M. [http://www.ncbi.nlm.nih.gov/pubmed/10792480 Morphological and immunophenotypic variations in malignant melanoma]. ''Histopathology'' 2000 May;36(5):387-402.
	* Shain AH, Yeh I, Kovalyshyn I, Sriharan A, Talevich E, Gagnon A, Dummer R, North J, Pincus L, Ruben B, Rickaby W, D’Arrigo C, Robson A, and Bastian BC.[http~~://https~~://www.nejm.org/doi/pdf/10.1056/NEJMoa1502583 The Genetic Evolution of Melanoma from Precursor Lesions]. ''New England Journal of Medicine'' 2015 Nov;373:1926-1936.		* Shain AH, Yeh I, Kovalyshyn I, Sriharan A, Talevich E, Gagnon A, Dummer R, North J, Pincus L, Ruben B, Rickaby W, D’Arrigo C, Robson A, and Bastian BC.[http://www.nejm.org/doi/pdf/10.1056/NEJMoa1502583 The Genetic Evolution of Melanoma from Precursor Lesions]. ''New England Journal of Medicine'' 2015 Nov;373:1926-1936.

	=== Images ===		=== Images ===

Peter Anderson: /* Journal Articles */

2015-11-12T14:17:00Z

Journal Articles

← Older revision		Revision as of 09:17, 12 November 2015
Line 31:		Line 31:
	=== Journal Articles ===		=== Journal Articles ===
	* Banerjee SS, Harris M. [http://www.ncbi.nlm.nih.gov/pubmed/10792480 Morphological and immunophenotypic variations in malignant melanoma]. ''Histopathology'' 2000 May;36(5):387-402.		* Banerjee SS, Harris M. [http://www.ncbi.nlm.nih.gov/pubmed/10792480 Morphological and immunophenotypic variations in malignant melanoma]. ''Histopathology'' 2000 May;36(5):387-402.
	* Shain AH, Yeh I, Kovalyshyn I, Sriharan A, Talevich E, Gagnon A, Dummer R, North J, Pincus L, Ruben B, Rickaby W, D’Arrigo C, Robson A, and Bastian BC.[http://~~http~~://www.nejm.org/doi/pdf/10.1056/NEJMoa1502583 The Genetic Evolution of Melanoma from Precursor Lesions]. ''New England Journal of Medicine'' 2015 Nov;373:1926-1936.		* Shain AH, Yeh I, Kovalyshyn I, Sriharan A, Talevich E, Gagnon A, Dummer R, North J, Pincus L, Ruben B, Rickaby W, D’Arrigo C, Robson A, and Bastian BC.[http://https://www.nejm.org/doi/pdf/10.1056/NEJMoa1502583 The Genetic Evolution of Melanoma from Precursor Lesions]. ''New England Journal of Medicine'' 2015 Nov;373:1926-1936.

	=== Images ===		=== Images ===

Peter Anderson: /* Journal Articles */

2015-11-12T14:11:49Z

Journal Articles

← Older revision		Revision as of 09:11, 12 November 2015
Line 31:		Line 31:
	=== Journal Articles ===		=== Journal Articles ===
	* Banerjee SS, Harris M. [http://www.ncbi.nlm.nih.gov/pubmed/10792480 Morphological and immunophenotypic variations in malignant melanoma]. ''Histopathology'' 2000 May;36(5):387-402.		* Banerjee SS, Harris M. [http://www.ncbi.nlm.nih.gov/pubmed/10792480 Morphological and immunophenotypic variations in malignant melanoma]. ''Histopathology'' 2000 May;36(5):387-402.
			* Shain AH, Yeh I, Kovalyshyn I, Sriharan A, Talevich E, Gagnon A, Dummer R, North J, Pincus L, Ruben B, Rickaby W, D’Arrigo C, Robson A, and Bastian BC.[http://http://www.nejm.org/doi/pdf/10.1056/NEJMoa1502583 The Genetic Evolution of Melanoma from Precursor Lesions]. ''New England Journal of Medicine'' 2015 Nov;373:1926-1936.

	=== Images ===		=== Images ===

Seung Park at 16:25, 3 January 2014

2014-01-03T16:25:06Z

← Older revision		Revision as of 11:25, 3 January 2014
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	File:IPLab7Melanoma8.jpg\|This is a high-power photomicrograph of the main tumor mass showing the cellular details. The individual melanoma cells contain large nuclei with irregular contours having chromatin clumped at the periphery of the nuclear membrane and prominent red (eosinophilic) nucleoli.		File:IPLab7Melanoma8.jpg\|This is a high-power photomicrograph of the main tumor mass showing the cellular details. The individual melanoma cells contain large nuclei with irregular contours having chromatin clumped at the periphery of the nuclear membrane and prominent red (eosinophilic) nucleoli.
	</gallery>		</gallery>

			== Virtual Microscopy ==
			<peir-vm>IPLab7Melanoma</peir-vm>

	== Study Question ==		== Study Question ==

Seung Park: /* Images */

2013-08-30T01:40:50Z

Images

← Older revision		Revision as of 20:40, 29 August 2013
Line 30:		Line 30:

	=== Images ===		=== Images ===
	* [~~http://peir.path.uab.edu~~/library/index.php?/tags/2148-melanoma PEIR Digital Library: Melanoma Images]		* [{{SERVER}}/library/index.php?/tags/2148-melanoma PEIR Digital Library: Melanoma Images]
	* [http://library.med.utah.edu/WebPath/NEOHTML/NEOPLIDX.html WebPath: Neoplasia]		* [http://library.med.utah.edu/WebPath/NEOHTML/NEOPLIDX.html WebPath: Neoplasia]

Seung Park: /* Related IPLab Cases */

2013-08-23T19:49:55Z

Related IPLab Cases

← Older revision		Revision as of 14:49, 23 August 2013
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	* [http://peir.path.uab.edu/library/index.php?/tags/2148-melanoma PEIR Digital Library: Melanoma Images]		* [http://peir.path.uab.edu/library/index.php?/tags/2148-melanoma PEIR Digital Library: Melanoma Images]
	* [http://library.med.utah.edu/WebPath/NEOHTML/NEOPLIDX.html WebPath: Neoplasia]		* [http://library.med.utah.edu/WebPath/NEOHTML/NEOPLIDX.html WebPath: Neoplasia]

	~~== Related IPLab Cases ==~~


	{{IPLab 7}}		{{IPLab 7}}

	[[Category: IPLab:Lab 7]]		[[Category: IPLab:Lab 7]]

Seung Park: /* Images */

2013-08-23T19:49:38Z

Images

← Older revision		Revision as of 14:49, 23 August 2013
Line 30:		Line 30:

	=== Images ===		=== Images ===
			* [http://peir.path.uab.edu/library/index.php?/tags/2148-melanoma PEIR Digital Library: Melanoma Images]
			* [http://library.med.utah.edu/WebPath/NEOHTML/NEOPLIDX.html WebPath: Neoplasia]

	== Related IPLab Cases ==		== Related IPLab Cases ==

Seung Park: /* Journal Articles */

2013-08-23T19:47:15Z

Journal Articles

← Older revision		Revision as of 14:47, 23 August 2013
Line 27:		Line 27:

	=== Journal Articles ===		=== Journal Articles ===
			* Banerjee SS, Harris M. [http://www.ncbi.nlm.nih.gov/pubmed/10792480 Morphological and immunophenotypic variations in malignant melanoma]. ''Histopathology'' 2000 May;36(5):387-402.

	=== Images ===		=== Images ===

Seung Park: /* Reference */

2013-08-23T19:46:29Z

Reference

← Older revision		Revision as of 14:46, 23 August 2013
Line 21:		Line 21:
	== Additional Resources ==		== Additional Resources ==
	=== Reference ===		=== Reference ===
			* [http://emedicine.medscape.com/article/1100753-overview eMedicine Medical Library: Cutaneous Melanoma]
			* [http://emedicine.medscape.com/article/280245-overview eMedicine Medical Library: Malignant Melanoma]
			* [http://emedicine.medscape.com/article/846566-overview eMedicine Medical Library: Skin Cancer -- Melanoma]
			* [http://www.merckmanuals.com/professional/dermatologic_disorders/cancers_of_the_skin/melanoma.html Merck Manual: Melanoma]

	=== Journal Articles ===		=== Journal Articles ===

← Older revision		Revision as of 21:14, 8 July 2020
Line 6:		Line 6:
	File:IPLab7Melanoma1.jpg\|This is a gross photograph of skin with melanoma. Note the black pigment, multiple satellite nodules, and focal ulceration. Some of the satellite nodules affect the nipple.		File:IPLab7Melanoma1.jpg\|This is a gross photograph of skin with melanoma. Note the black pigment, multiple satellite nodules, and focal ulceration. Some of the satellite nodules affect the nipple.
	File:IPLab7Melanoma2.jpg\|This is a gross photograph of lymph nodes almost entirely replaced by black pigment (melanin).		File:IPLab7Melanoma2.jpg\|This is a gross photograph of lymph nodes almost entirely replaced by black pigment (melanin).
	File:~~IPLab7Melanoma3~~.jpg\|This is a low-power photomicrograph of lymph node that is almost completely replaced/filled with tumor. This lymph node has a capsule (1) and some remaining lymphocytes (2) but the remainder of the node is replaced by tumor cells.		File:IPLab7Melanoma3b.jpg\|This is a low-power photomicrograph of lymph node that is almost completely replaced/filled with tumor. This lymph node has a capsule (1) and some remaining lymphocytes (2) but the remainder of the node is replaced by tumor cells.
	File:~~IPLab7Melanoma4~~.jpg\|This higher-power photomicrograph shows the remaining portion of lymph node (arrow). The rest of the lymph node is invaded by a neoplasm composed of cells with lighter eosinophilic cytoplasm and pigment.		File:IPLab7Melanoma4b.jpg\|This higher-power photomicrograph shows the remaining portion of lymph node (arrow). The rest of the lymph node is invaded by a neoplasm composed of cells with lighter eosinophilic cytoplasm and pigment.
	File:~~IPLab7Melanoma5~~.jpg\|This is a higher-magnification showing the abundant extracellular melanin (arrows) surrounding the tumor cells. This section of neoplasm shows the numerous cells with abundant cytoplasm and brown pigment within the cytoplasm of some of these cells.		File:IPLab7Melanoma5b.jpg\|This is a higher-magnification showing the abundant extracellular melanin (arrows) surrounding the tumor cells. This section of neoplasm shows the numerous cells with abundant cytoplasm and brown pigment within the cytoplasm of some of these cells.
	File:~~IPLab7Melanoma6~~.jpg\|This is a higher magnification showing the abundant extracellular melanin surrounding the tumor cells (brown pigment).		File:IPLab7Melanoma6b.jpg\|This is a higher magnification showing the abundant extracellular melanin surrounding the tumor cells (brown pigment).
	File:~~IPLab7Melanoma7~~.jpg\|This is a high-power photomicrograph of the main tumor mass with the cells growing as poorly formed nests and sheets of cells. There is little if any pigment in this section.		File:IPLab7Melanoma7b.jpg\|This is a high-power photomicrograph of the main tumor mass with the cells growing as poorly formed nests and sheets of cells. There is little if any pigment in this section.
	File:IPLab7Melanoma8.jpg\|This is a high-power photomicrograph of the main tumor mass showing the cellular details. The individual melanoma cells contain large nuclei with irregular contours having chromatin clumped at the periphery of the nuclear membrane and prominent red (eosinophilic) nucleoli.		File:IPLab7Melanoma8.jpg\|This is a high-power photomicrograph of the main tumor mass showing the cellular details. The individual melanoma cells contain large nuclei with irregular contours having chromatin clumped at the periphery of the nuclear membrane and prominent red (eosinophilic) nucleoli.
	</gallery>		</gallery>