IPLab:Lab 6:Scleroderma - Revision history

Peter Anderson: /* Autopsy Findings */

2020-07-08T23:38:40Z

‎Autopsy Findings

Peter Anderson: /* Clinical Summary */

2020-07-08T23:38:33Z

‎Clinical Summary

Peter Anderson: /* Virtual Microscopy */

2015-09-16T19:40:28Z

‎Virtual Microscopy

Seung Park at 20:38, 21 February 2014

2014-02-21T20:38:55Z

Seung Park: /* Virtual Microscopy */

2014-01-03T16:18:31Z

‎Virtual Microscopy

Seung Park: /* Virtual Microscopy */

2014-01-03T16:18:10Z

‎Virtual Microscopy

Seung Park at 16:17, 3 January 2014

2014-01-03T16:17:52Z

Seung Park: /* Journal Articles */

2013-08-30T01:35:39Z

‎Journal Articles

Seung Park: /* Images */

2013-08-30T01:35:31Z

‎Images

Seung Park: /* Related IPLab Cases */

2013-08-22T23:49:22Z

‎Related IPLab Cases

← Older revision		Revision as of 23:38, 8 July 2020
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	Upon opening the thorax at autopsy there was 600 cc of cloudy serous fluid in each hemithorax and 100 cc of similar fluid in the pericardial sac. The heart weighed 530 grams and there was thickening of both the left and right ventricular walls. The liver weighed 1880 grams and was congested. The spleen weighed 200 grams and was also congested. The combined lung weight was 1875 grams; the lungs were markedly fibrotic with severe emphysema. In addition, dermal thickening was evident throughout the body and the wall of the esophagus was thickened and firm.		Upon opening the thorax at autopsy there was 600 cc of cloudy serous fluid in each hemithorax and 100 cc of similar fluid in the pericardial sac. The heart weighed 530 grams and there was thickening of both the left and right ventricular walls. The liver weighed 1880 grams and was congested. The spleen weighed 200 grams and was also congested. The combined lung weight was 1875 grams; the lungs were markedly fibrotic with severe emphysema. In addition, dermal thickening was evident throughout the body and the wall of the esophagus was thickened and firm.
−
−	~~== Autopsy Findings ==~~
−	Upon opening the thorax there was 600 cc of cloudy serous fluid in each hemithorax and 100 cc of similar fluid in the pericardial sac. The heart weighed 530 grams and there was thickening of both the left and right ventricular walls. The liver weighed 1880 grams and was congested. The spleen weighed 200 grams and was also congested. The combined lung weight was 1875 grams; the lungs were markedly fibrotic with severe emphysema. In addition, dermal thickening was evident throughout the body and the wall of the esophagus was thickened and firm.

	== Images ==		== Images ==

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 == Clinical Summary ==
 This 29-year-old black female had a history of scleroderma involving the lung, kidney, heart, and skin. Her main clinical problems centered on her restrictive lung disease. She was able to live at home with supplemental oxygen but recently she had developed edema, chest pain, weakness, light-headedness, and a loss of appetite. The patient was admitted to the hospital with a working diagnosis of congestive heart failure brought on by her lung disease. Echocardiographic evaluation revealed a pericardial effusion that was tapped. Soon after this procedure her respiratory status degenerated and she required intubation. Despite aggressive supportive treatment for her cardiac and pulmonary problems, she could not be weaned from the ventilator. Two weeks after admission she became febrile and Gram positive cocci were isolated from sputum culture. She was placed on antibiotics but her condition deteriorated and she developed bradycardia followed by electromechanical dissociation (EMD).
 == Autopsy Findings ==

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 == Virtual Microscopy ==
-=== Lung ===
+=== Lung: Scleroderma ===
 <peir-vm>IPLab6Scleroderma</peir-vm>
-=== Skin ===
+=== Normal Lung ===
 <peir-vm>IPLab6Scleroderma_Skin</peir-vm>
 == Study Questions ==

@@ Line 15: / Line 15: @@
 == Virtual Microscopy ==
 === Skin ===
 <peir-vm>IPLab6Scleroderma_Skin</peir-vm>

← Older revision		Revision as of 16:18, 3 January 2014
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	== Virtual Microscopy ==		== Virtual Microscopy ==
		+	=== Skin ===
	<peir-vm>IPLab6Scleroderma_Skin</peir-vm>		<peir-vm>IPLab6Scleroderma_Skin</peir-vm>

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 File:IPLab6Scleroderma5.jpg|This is a gross photograph of the heart from this case. There is thickening of the left ventricular wall and some thickening of the right ventricle as well.
 </gallery>
 == Study Questions ==

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 * [http://emedicine.medscape.com/article/1064663-overview eMedicine Medical Library: CREST Syndrome]
 * [http://www.merckmanuals.com/professional/musculoskeletal_and_connective_tissue_disorders/autoimmune_rheumatic_disorders/systemic_sclerosis.html Merck Manual: Systemic Sclerosis]
 === Images ===

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 === Images ===
-* [http://peir,path.uab.edu/library/index.php?/tags/2144-scleroderma PEIR Digital Library: Scleroderma Images]
+* [{{SERVER}}/library/index.php?/tags/2144-scleroderma PEIR Digital Library: Scleroderma Images]
 == Related IPLab Cases ==

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 == Related IPLab Cases ==
 * [[IPLab:Lab 2:Hypertrophy|Lab 2: Heart: Myocardial Hypertrophy]]
-* [[IPLab:Lab 5:&alpha; 1 Antitrypsin Deficiency|Lab 5: Lung: Alpha 1-Antitrypsin Deficiency]]
+* [[IPLab:Lab 5:&alpha;1 Antitrypsin Deficiency|Lab 5: Lung: &alpha;1-Antitrypsin Deficiency]]
 {{IPLab 6}}
 [[Category: IPLab:Lab 6]]