IPLab:Lab 6:Graves Disease - Revision history

Peter Anderson: /* Images */

2020-07-08T23:18:19Z

‎Images

Peter Anderson: /* Images */

2020-07-08T21:38:54Z

‎Images

Peter Anderson: /* Images */

2020-07-08T21:36:16Z

‎Images

Peter Anderson: /* Autopsy Findings */

2020-07-08T20:53:47Z

‎Autopsy Findings

Peter Anderson: /* Clinical Summary */

2020-07-08T20:53:38Z

‎Clinical Summary

Peter Anderson: /* Journal Articles */

2016-10-20T13:01:14Z

‎Journal Articles

Seung Park at 16:17, 3 January 2014

2014-01-03T16:17:00Z

Seung Park: /* Images */

2013-08-30T01:34:53Z

‎Images

Seung Park: /* Related IPLab Cases */

2013-08-22T21:30:27Z

‎Related IPLab Cases

Seung Park: /* Related IPLab Cases */

2013-08-22T21:30:19Z

‎Related IPLab Cases

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 File:IPLab6GravesDisease1b.jpg|This is a photograph of the thyroid from this case. Note that the gland is enlarged and is dark red.
 File:IPLab6GravesDisease2.jpg|This is a low-power photomicrograph of thyroid tissue from this case. The tissue is very cellular with very little colloid.
-File:IPLab6GravesDisease3.jpg|This is a higher-power photomicrograph of thyroid. The tissue is very cellular and there is little colloid.
+File:IPLab6GravesDisease3x.jpg|This is a higher-power photomicrograph of thyroid. The tissue is very cellular and there is much less colloid (C) filling the glands than is normally seen.
 File:IPLab6GravesDisease4.jpg|This is a high-power photomicrograph of thyroid. Note the cellularity of the tissue with marked infolding of the epithelial tissue.
-File:IPLab6GravesDisease5.jpg|This is a high-power photomicrograph of thyroid. Note the papillary projections and the moth-eaten appearance of the colloid. This appearance indicates active absorption of the colloid to form thyroglobulin.
+File:IPLab6GravesDisease5x.jpg|This is a high-power photomicrograph of thyroid. Note the papillary projections and the “scalloped” or “moth-eaten” appearance (arrows) of the colloid (C). This appearance indicates active absorption of the colloid to form thyroglobulin.
 File:IPLab6GravesDisease6.jpg|This is a gross photograph of a thyroid from a case of nodular goiter.
 File:IPLab6GravesDisease7b.jpg|Closer view of cut surface of the thyroid with nodular goiter. Note the multilobular appearance of the tissue.

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 File:IPLab6GravesDisease5.jpg|This is a high-power photomicrograph of thyroid. Note the papillary projections and the moth-eaten appearance of the colloid. This appearance indicates active absorption of the colloid to form thyroglobulin.
 File:IPLab6GravesDisease6.jpg|This is a gross photograph of a thyroid from a case of nodular goiter.
-File:IPLab6GravesDisease7.jpg|Closer view of cut surface of the thyroid with nodular goiter. Note the multilobular appearance of the tissue.
+File:IPLab6GravesDisease7b.jpg|Closer view of cut surface of the thyroid with nodular goiter. Note the multilobular appearance of the tissue.
 </gallery>

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 == Images ==
 <gallery heights="250px" widths="250px">
-File:IPLab6GravesDisease1.jpg|This is a photograph of the thyroid from this case. Note that the gland is enlarged and is dark red.
+File:IPLab6GravesDisease1b.jpg|This is a photograph of the thyroid from this case. Note that the gland is enlarged and is dark red.
 File:IPLab6GravesDisease2.jpg|This is a low-power photomicrograph of thyroid tissue from this case. The tissue is very cellular with very little colloid.
 File:IPLab6GravesDisease3.jpg|This is a higher-power photomicrograph of thyroid. The tissue is very cellular and there is little colloid.

@@ Line 1: / Line 1: @@
 == Clinical Summary ==
 This 18-year-old girl presented with complaints of swelling in the neck, weight loss, bulging of the eyes, tremor, decreased heat tolerance, loose stools, and occasional palpitations. Physical examination revealed normal blood pressure, resting tachycardia of 110 beats per minute, mild exophthalmos, eyelid lag, and a diffusely enlarged thyroid gland. Pertinent laboratory findings were thyroxine (T4) level 30.8 mcg/dL, free thyroxine was 2.7 ng/dL , and thyroid stimulating hormone (TSH) was 0.22 mcIU/mL . She was given propylthiouracil until she became nearly euthyroid, at which time a thyroidectomy was done. The thyroid gland weighed 45 grams. It was beefy red in color and had a homogeneous fleshy consistency.
 == Images ==

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 == Clinical Summary ==
-This 18-year-old girl presented with complaints of swelling in the neck, weight loss, bulging of the eyes, tremor, decreased heat tolerance, loose stools, and occasional palpitations. Physical examination revealed normal blood pressure, resting tachycardia of 110 beats per minute, mild exophthalmos, eyelid lag, and a diffusely enlarged thyroid gland. Pertinent laboratory findings were thyroxine (T4) level 30.8 mcg/dL, free thyroxine was 2.7 ng/dL, and thyroid stimulating hormone (TSH) was 0.22 mcIU/mL. She was given propylthiouracil until she became nearly euthyroid, at which time a thyroidectomy was done.
+This 18-year-old girl presented with complaints of swelling in the neck, weight loss, bulging of the eyes, tremor, decreased heat tolerance, loose stools, and occasional palpitations. Physical examination revealed normal blood pressure, resting tachycardia of 110 beats per minute, mild exophthalmos, eyelid lag, and a diffusely enlarged thyroid gland. Pertinent laboratory findings were thyroxine (T4) level 30.8 mcg/dL, free thyroxine was 2.7 ng/dL , and thyroid stimulating hormone (TSH) was 0.22 mcIU/mL . She was given propylthiouracil until she became nearly euthyroid, at which time a thyroidectomy was done. The thyroid gland weighed 45 grams. It was beefy red in color and had a homogeneous fleshy consistency.
 == Autopsy Findings ==

← Older revision		Revision as of 13:01, 20 October 2016
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	=== Journal Articles ===		=== Journal Articles ===
		+	* Smith TJ and Hegedüs L. [http://www.nejm.org/doi/full/10.1056/NEJMra1510030 Graves’ Disease]. NEJM 2016 375:1552-1565.
	* Fraser T, Green D. [http://www.ncbi.nlm.nih.gov/pubmed/11554873 Weathering the storm: beta-blockade and the potential for disaster in severe hyperthyroidism]. ''Emerg Med (Fremantle)'' 2001 Sep;13(3):376-80.		* Fraser T, Green D. [http://www.ncbi.nlm.nih.gov/pubmed/11554873 Weathering the storm: beta-blockade and the potential for disaster in severe hyperthyroidism]. ''Emerg Med (Fremantle)'' 2001 Sep;13(3):376-80.

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 === Images ===
-* [http://peir.path.uab.edu/library/index.php?/tags/15-endocrine/140-thyroid/651-autoimmune_thyroiditis PEIR Digital Library: Autoimmune Thyroiditis Images]
+* [{{SERVER}}/library/index.php?/tags/15-endocrine/140-thyroid/651-autoimmune_thyroiditis PEIR Digital Library: Autoimmune Thyroiditis Images]
 * [http://library.med.utah.edu/WebPath/ENDOHTML/ENDOIDX.html Webpath: Endocrine Pathology]

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 == Related IPLab Cases ==
-* [[IPLab:Lab 6:Hashimoto's Thyroiditis|Lab 6: Thyroid: Hashimotos Thyroiditis]]
+* [[IPLab:Lab 6:Hashimoto's Thyroiditis|Lab 6: Thyroid: Hashimoto's Thyroiditis]]
 * [[IPLab:Lab 7:Adenoma|Lab 7: Thyroid: Adenoma]]