IPLab:Lab 4:Chronic Passive Congestion - Revision history

Peter Anderson: /* Autopsy Findings */

2020-06-24T01:56:14Z

Autopsy Findings

← Older revision		Revision as of 20:56, 23 June 2020
Line 3:		Line 3:

	At autopsy the lungs were congested and edematous with evidence of lobar pneumonia. The heart weighed 540 grams and showed 75 to 95% atherosclerotic stenosis of all the major coronary arteries. The right and left ventricles were markedly dilated. The ventricular walls were extremely thin with patchy areas of subendocardial fibrosis. The liver weighed 1630 grams and displayed the classic "nutmeg appearance" of chronic passive hepatic congestion on cut surface.		At autopsy the lungs were congested and edematous with evidence of lobar pneumonia. The heart weighed 540 grams and showed 75 to 95% atherosclerotic stenosis of all the major coronary arteries. The right and left ventricles were markedly dilated. The ventricular walls were extremely thin with patchy areas of subendocardial fibrosis. The liver weighed 1630 grams and displayed the classic "nutmeg appearance" of chronic passive hepatic congestion on cut surface.

	~~== Autopsy Findings ==~~

	At autopsy the lungs were congested and edematous with evidence of lobar pneumonia. The heart weighed 540 grams and showed 75 to 95% atherosclerotic stenosis of all the major coronary arteries. The right and left ventricles were markedly dilated. The ventricular walls were extremely thin with patchy areas of subendocardial fibrosis. The liver weighed 1630 grams and displayed the classic "nutmeg appearance" of chronic passive hepatic congestion on cut surface.

	== Images ==		== Images ==

Peter Anderson: /* Clinical Summary */

2020-06-24T01:56:06Z

Clinical Summary

← Older revision		Revision as of 20:56, 23 June 2020
Line 2:		Line 2:
	This 57-year-old male was hospitalized with a three-month history of a dry, hacking cough, dyspnea, and chest pain. He was diagnosed as having congestive heart failure. There was no evidence of myocardial infarction, but renal and hepatic functions were decreased. The patient developed refractory congestive heart failure and renal failure. The patient's cardiac index was marginal and he was classified as a having congestive cardiomyopathy. The patient had a cardiorespiratory arrest and died two months after admission.		This 57-year-old male was hospitalized with a three-month history of a dry, hacking cough, dyspnea, and chest pain. He was diagnosed as having congestive heart failure. There was no evidence of myocardial infarction, but renal and hepatic functions were decreased. The patient developed refractory congestive heart failure and renal failure. The patient's cardiac index was marginal and he was classified as a having congestive cardiomyopathy. The patient had a cardiorespiratory arrest and died two months after admission.

	At autopsy the lungs were congested and edematous with evidence of lobar pneumonia. The heart weighed 540 grams and showed 75 to 95% atherosclerotic stenosis of all the major coronary arteries. The right and left ventricles were markedly dilated. The ventricular walls were extremely thin with patchy areas of subendocardial fibrosis. The liver weighed 1630 grams and displayed the classic "nutmeg appearance" of chronic passive hepatic congestion on cut surface.		At autopsy the lungs were congested and edematous with evidence of lobar pneumonia. The heart weighed 540 grams and showed 75 to 95% atherosclerotic stenosis of all the major coronary arteries. The right and left ventricles were markedly dilated. The ventricular walls were extremely thin with patchy areas of subendocardial fibrosis. The liver weighed 1630 grams and displayed the classic "nutmeg appearance" of chronic passive hepatic congestion on cut surface.

	== Autopsy Findings ==		== Autopsy Findings ==

Peter Anderson: /* Clinical Summary */

2020-06-24T01:55:24Z

Clinical Summary

← Older revision		Revision as of 20:55, 23 June 2020
Line 1:		Line 1:
	== Clinical Summary ==		== Clinical Summary ==
			This 57-year-old male was hospitalized with a three-month history of a dry, hacking cough, dyspnea, and chest pain. He was diagnosed as having congestive heart failure. There was no evidence of myocardial infarction, but renal and hepatic functions were decreased. The patient developed refractory congestive heart failure and renal failure. The patient's cardiac index was marginal and he was classified as a having congestive cardiomyopathy. The patient had a cardiorespiratory arrest and died two months after admission.

	~~This 57-year-old male was hospitalized~~ with ~~a three-month history~~ of ~~a dry, hacking cough, dyspnea, and chest pain~~. ~~He was diagnosed as having congestive~~ heart ~~failure due~~ to ~~viral myocarditis. There was no evidence~~ of ~~myocardial infarction, but renal and hepatic functions were decreased~~. The ~~patient developed refractory congestive heart failure~~ and ~~renal failure~~. The ~~patient's cardiac index was marginal and he was classified as a having congestive cardiomyopathy~~. The ~~patient had a cardiorespiratory arrest~~ and ~~died two months after admission~~.		At autopsy the lungs were congested and edematous with evidence of lobar pneumonia. The heart weighed 540 grams and showed 75 to 95% atherosclerotic stenosis of all the major coronary arteries. The right and left ventricles were markedly dilated. The ventricular walls were extremely thin with patchy areas of subendocardial fibrosis. The liver weighed 1630 grams and displayed the classic "nutmeg appearance" of chronic passive hepatic congestion on cut surface.

	== Autopsy Findings ==		== Autopsy Findings ==

Peter Anderson: /* Virtual Microscopy */

2015-09-16T19:17:48Z

Virtual Microscopy

← Older revision		Revision as of 14:17, 16 September 2015
Line 21:		Line 21:

	== Virtual Microscopy ==		== Virtual Microscopy ==
			=== Liver Chronic Passive Congestion ===
	<peir-vm>IPLab4ChronicPassiveCongestion</peir-vm>		<peir-vm>IPLab4ChronicPassiveCongestion</peir-vm>

			=== Normal Liver ===
			<peir-vm>UAB-Histology-00149</peir-vm>

	== Study Questions ==		== Study Questions ==

Seung Park at 16:11, 3 January 2014

2014-01-03T16:11:10Z

← Older revision		Revision as of 11:11, 3 January 2014
Line 19:		Line 19:
	File:IPLab4ChronicPassiveCongestion9.jpg\|This is a gross photograph of the cut surface of a liver with chronic passive congestion (left) compared to the cut surface of a nutmeg (right).		File:IPLab4ChronicPassiveCongestion9.jpg\|This is a gross photograph of the cut surface of a liver with chronic passive congestion (left) compared to the cut surface of a nutmeg (right).
	</gallery>		</gallery>

			== Virtual Microscopy ==
			<peir-vm>IPLab4ChronicPassiveCongestion</peir-vm>

	== Study Questions ==		== Study Questions ==

Seung Park: /* Images */

2013-08-30T01:30:43Z

Images

← Older revision		Revision as of 20:30, 29 August 2013
Line 35:		Line 35:

	=== Images ===		=== Images ===
	* [~~http://peir.path.uab.edu~~/library/index.php?/tags/672-chronic_passive_congestion PEIR Digital Library: Chronic Passive Congestion Images]		* [{{SERVER}}/library/index.php?/tags/672-chronic_passive_congestion PEIR Digital Library: Chronic Passive Congestion Images]
	* [http://library.med.utah.edu/WebPath/LIVEHTML/LIVERIDX.html#1 Webpath: Hepatic Pathology]		* [http://library.med.utah.edu/WebPath/LIVEHTML/LIVERIDX.html#1 Webpath: Hepatic Pathology]

Seung Park at 02:37, 22 August 2013

2013-08-22T02:37:00Z

@@ Line 23: / Line 23: @@
 * <spoiler text="What is the most common cause of chronic passive congestion of the liver?">Right-sided heart failure. Also, obstruction of the inferior vena cava or hepatic vein (usually associated with neoplasia and/or a hypercoagulable state leading to thrombosis) can cause hepatic congestion</spoiler>
 * <spoiler text="Why is the central vein region most severely affected by chronic passive congestion?">The central vein region is farthest away from the arterial (oxygenated) blood so this region has the lowest oxygen tension anyway. With congestion and stasis, this central vein region becomes hypoxic which results in liver cell atrophy and necrosis. The peripheral regions are hypoxic but and develop fatty change. Thus, the dark red, congested, and necrotic central vein region that is surrounded by yellow fatty change gives the morphology that is termed "nutmeg liver."</spoiler>
 {{IPLab 4}}
 [[Category: IPLab:Lab 4]]

Seung Park at 14:54, 21 August 2013

2013-08-21T14:54:41Z

← Older revision		Revision as of 09:54, 21 August 2013
Line 19:		Line 19:
	File:IPLab4ChronicPassiveCongestion9.jpg\|This is a gross photograph of the cut surface of a liver with chronic passive congestion (left) compared to the cut surface of a nutmeg (right).		File:IPLab4ChronicPassiveCongestion9.jpg\|This is a gross photograph of the cut surface of a liver with chronic passive congestion (left) compared to the cut surface of a nutmeg (right).
	</gallery>		</gallery>

			== Study Questions ==
			* <spoiler text="What is the most common cause of chronic passive congestion of the liver?">Right-sided heart failure. Also, obstruction of the inferior vena cava or hepatic vein (usually associated with neoplasia and/or a hypercoagulable state leading to thrombosis) can cause hepatic congestion</spoiler>
			* <spoiler text="Why is the central vein region most severely affected by chronic passive congestion?">The central vein region is farthest away from the arterial (oxygenated) blood so this region has the lowest oxygen tension anyway. With congestion and stasis, this central vein region becomes hypoxic which results in liver cell atrophy and necrosis. The peripheral regions are hypoxic but and develop fatty change. Thus, the dark red, congested, and necrotic central vein region that is surrounded by yellow fatty change gives the morphology that is termed "nutmeg liver."</spoiler>

	{{IPLab 4}}		{{IPLab 4}}

	[[Category: IPLab:Lab 4]]		[[Category: IPLab:Lab 4]]

Peter Anderson at 14:27, 21 August 2013

2013-08-21T14:27:17Z

← Older revision		Revision as of 09:27, 21 August 2013
Line 5:		Line 5:
	== Autopsy Findings ==		== Autopsy Findings ==

	At autopsy the lungs were congested and edematous with evidence of lobar pneumonia. The heart weighed 540 grams and showed 75 to 95% atherosclerotic stenosis of all the major coronary arteries. The right and left ventricles were markedly dilated. The ventricular walls were extremely thin with patchy areas of subendocardial fibrosis. The liver weighed 1630 grams and displayed the classic "nutmeg appearance" of chronic passive hepatic congestion on cut surface. == Images ==		At autopsy the lungs were congested and edematous with evidence of lobar pneumonia. The heart weighed 540 grams and showed 75 to 95% atherosclerotic stenosis of all the major coronary arteries. The right and left ventricles were markedly dilated. The ventricular walls were extremely thin with patchy areas of subendocardial fibrosis. The liver weighed 1630 grams and displayed the classic "nutmeg appearance" of chronic passive hepatic congestion on cut surface.

			== Images ==
	<gallery heights="250px" widths="250px">		<gallery heights="250px" widths="250px">
	File:IPLab4ChronicPassiveCongestion1.jpg\|This is a gross photograph of a liver demonstrating chronic passive congestion. Note the accentuation of the centrilobular pattern evidenced by the dark-brown-staining areas in this tissue.		File:IPLab4ChronicPassiveCongestion1.jpg\|This is a gross photograph of a liver demonstrating chronic passive congestion. Note the accentuation of the centrilobular pattern evidenced by the dark-brown-staining areas in this tissue.

Peter Anderson at 14:26, 21 August 2013

2013-08-21T14:26:58Z

← Older revision		Revision as of 09:26, 21 August 2013
Line 1:		Line 1:
	== Images ==		== Clinical Summary ==

			This 57-year-old male was hospitalized with a three-month history of a dry, hacking cough, dyspnea, and chest pain. He was diagnosed as having congestive heart failure due to viral myocarditis. There was no evidence of myocardial infarction, but renal and hepatic functions were decreased. The patient developed refractory congestive heart failure and renal failure. The patient's cardiac index was marginal and he was classified as a having congestive cardiomyopathy. The patient had a cardiorespiratory arrest and died two months after admission.

			== Autopsy Findings ==

			At autopsy the lungs were congested and edematous with evidence of lobar pneumonia. The heart weighed 540 grams and showed 75 to 95% atherosclerotic stenosis of all the major coronary arteries. The right and left ventricles were markedly dilated. The ventricular walls were extremely thin with patchy areas of subendocardial fibrosis. The liver weighed 1630 grams and displayed the classic "nutmeg appearance" of chronic passive hepatic congestion on cut surface. == Images ==
	<gallery heights="250px" widths="250px">		<gallery heights="250px" widths="250px">
	File:IPLab4ChronicPassiveCongestion1.jpg\|This is a gross photograph of a liver demonstrating chronic passive congestion. Note the accentuation of the centrilobular pattern evidenced by the dark-brown-staining areas in this tissue.		File:IPLab4ChronicPassiveCongestion1.jpg\|This is a gross photograph of a liver demonstrating chronic passive congestion. Note the accentuation of the centrilobular pattern evidenced by the dark-brown-staining areas in this tissue.