IPLab:Lab 3:Sarcoidosis - Revision history

Peter Anderson: /* Journal Articles */

2021-09-13T18:16:35Z

‎Journal Articles

Peter Anderson: /* Images */

2020-06-19T23:17:04Z

‎Images

Peter Anderson: /* Virtual Microscopy */

2015-09-17T19:27:42Z

‎Virtual Microscopy

Seung Park at 16:05, 3 January 2014

2014-01-03T16:05:37Z

Seung Park: /* Images */

2013-08-30T01:26:11Z

‎Images

Seung Park: /* Related IPLab Cases */

2013-08-22T02:18:50Z

‎Related IPLab Cases

Seung Park: /* Related IPLab Cases */

2013-08-19T15:42:34Z

‎Related IPLab Cases

Seung Park: /* Related IPLab Cases */

2013-08-19T15:42:23Z

‎Related IPLab Cases

Seung Park: /* Images */

2013-08-19T15:41:40Z

‎Images

Seung Park: /* Journal Articles */

2013-08-19T15:37:51Z

‎Journal Articles

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 === Journal Articles ===
 * English JC, Patel PJ, Greer KE.  [http://www.mdconsult.com/das/article/body/421068364-2/jorg=journal&source=MI&sp=11817316&sid=119276088/N/217466/1.html?issn= Sarcoidosis].  ''J Am Acad Dermatol'' 2001;44:725-43
 * Johns CJ, Michele TM.  [http://www.ncbi.nlm.nih.gov/pubmed/10195091 The clinical management of sarcoidosis. A 50-year experience at the Johns Hopkins Hospital].  ''Medicine (Baltimore)'' 1999 Mar;78(2):65-111.

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 <gallery heights="250px" widths="250px">
 File:IPLab3Sarcoidosis1.jpg|This is a low-power photomicrograph of a lymph node. Note the rather pale-pink color of the tissue with dark-staining cells found in only a few scattered areas. These darker cells represent the original lymphocytes of this lymphoid organ.
-File:IPLab3Sarcoidosis2.jpg|This photomicrograph of lymph node tissue illustrates a paucity of lymphocytes as well as numerous small, pale-staining nodules (arrows) throughout the tissue.
+File:IPLab3Sarcoidosis2b.jpg|This photomicrograph of lymph node tissue illustrates a paucity of lymphocytes as well as numerous small, pale-staining nodules (arrows) throughout the tissue.
-File:IPLab3Sarcoidosis3.jpg|This is a photomicrograph of the small nodules (arrows) seen in the previous image. Close examination reveals that they are composed of large macrophages (epithelioid macrophages). These small granulomas form multiple series of reaction centers throughout the lymph node. Note the remaining lymphocytes surrounding the granulomas.
+File:IPLab3Sarcoidosis3b.jpg|This is a photomicrograph of the small nodules (arrows) seen in the previous image. Close examination reveals that they are composed of large macrophages (epithelioid macrophages). These small granulomas form multiple series of reaction centers throughout the lymph node. Note the remaining lymphocytes surrounding the granulomas.
 File:IPLab3Sarcoidosis4.jpg|This photomicrograph of a single granuloma illustrates the individual macrophages (arrows) which make up the bulk of this tissue. There is an absence of necrosis in the center of the lesions in this case.
-File:IPLab3Sarcoidosis5.jpg|This is a photomicrograph of a multinucleated giant cell (1). In the center of this foreign body-containing giant cell there is a small asteroid body (2). There is no functional significance to this asteroid body.
+File:IPLab3Sarcoidosis5b.jpg|This is a photomicrograph of a multinucleated giant cell (1). In the center of this foreign body-containing giant cell there is a small asteroid body (2). There is no functional significance to this asteroid body.
 </gallery>

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 == Virtual Microscopy ==
 <peir-vm>IPLab3Sarcoidosis</peir-vm>
 == Study Questions ==

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 </gallery>
-Study Questions
+== Virtual Microscopy ==
 * <spoiler text="What is sarcoidosis?">The exact cause of sarcoidosis is unknown. Sarcoidosis is characterized by non-caseating granulomas in many tissues and organs.</spoiler>
 * <spoiler text="What is the characteristic phenotype of sarcoid granulomas?">The typical characteristic of a sarcoid granuloma is a non-caseating granuloma which consists of an aggregate of tightly-clustered epitheliod cells, often with Langhans’ or multinucleated giant cells. Occasionally, asteroid bodies may be seen.</spoiler>

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 === Images ===
-* [http://peir.path.uab.edu/library/index.php?/tags/531-sarcoidosis PEIR Digital Library: Sarcoidosis Images]
+* [{{SERVER}}/library/index.php?/tags/531-sarcoidosis PEIR Digital Library: Sarcoidosis Images]
 * [http://library.med.utah.edu/WebPath/LUNGHTML/LUNGIDX.html#2 WebPath: Granulomatous Disease]

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 * [http://library.med.utah.edu/WebPath/LUNGHTML/LUNGIDX.html#2 WebPath: Granulomatous Disease]
-=== Related IPLab Cases ===
+== Related IPLab Cases ==
 * [[IPLab:Lab 2:Metastatic Calcification|Lab 2: Lung: Metastatic Calcification]]
 {{IPLab 3}}
 [[Category: IPLab:Lab 3]]