IPLab:Lab 3:Sarcoidosis - Revision history

Peter Anderson: /* Journal Articles */

2021-09-13T18:16:35Z

Journal Articles

← Older revision		Revision as of 13:16, 13 September 2021
Line 32:		Line 32:

	=== Journal Articles ===		=== Journal Articles ===
			* Drent M, Crouser ED, Grunewald J. [https://www.nejm.org/doi/full/10.1056/NEJMra2101555 Challenges of Sarcoidosis and Its Management]. ''N Engl J Med'' 2021; 385:1018-1032
	* English JC, Patel PJ, Greer KE. [http://www.mdconsult.com/das/article/body/421068364-2/jorg=journal&source=MI&sp=11817316&sid=119276088/N/217466/1.html?issn= Sarcoidosis]. ''J Am Acad Dermatol'' 2001;44:725-43		* English JC, Patel PJ, Greer KE. [http://www.mdconsult.com/das/article/body/421068364-2/jorg=journal&source=MI&sp=11817316&sid=119276088/N/217466/1.html?issn= Sarcoidosis]. ''J Am Acad Dermatol'' 2001;44:725-43
	* Johns CJ, Michele TM. [http://www.ncbi.nlm.nih.gov/pubmed/10195091 The clinical management of sarcoidosis. A 50-year experience at the Johns Hopkins Hospital]. ''Medicine (Baltimore)'' 1999 Mar;78(2):65-111.		* Johns CJ, Michele TM. [http://www.ncbi.nlm.nih.gov/pubmed/10195091 The clinical management of sarcoidosis. A 50-year experience at the Johns Hopkins Hospital]. ''Medicine (Baltimore)'' 1999 Mar;78(2):65-111.

Peter Anderson: /* Images */

2020-06-19T23:17:04Z

Images

← Older revision		Revision as of 18:17, 19 June 2020
Line 5:		Line 5:
	<gallery heights="250px" widths="250px">		<gallery heights="250px" widths="250px">
	File:IPLab3Sarcoidosis1.jpg\|This is a low-power photomicrograph of a lymph node. Note the rather pale-pink color of the tissue with dark-staining cells found in only a few scattered areas. These darker cells represent the original lymphocytes of this lymphoid organ.		File:IPLab3Sarcoidosis1.jpg\|This is a low-power photomicrograph of a lymph node. Note the rather pale-pink color of the tissue with dark-staining cells found in only a few scattered areas. These darker cells represent the original lymphocytes of this lymphoid organ.
	File:~~IPLab3Sarcoidosis2~~.jpg\|This photomicrograph of lymph node tissue illustrates a paucity of lymphocytes as well as numerous small, pale-staining nodules (arrows) throughout the tissue.		File:IPLab3Sarcoidosis2b.jpg\|This photomicrograph of lymph node tissue illustrates a paucity of lymphocytes as well as numerous small, pale-staining nodules (arrows) throughout the tissue.
	File:~~IPLab3Sarcoidosis3~~.jpg\|This is a photomicrograph of the small nodules (arrows) seen in the previous image. Close examination reveals that they are composed of large macrophages (epithelioid macrophages). These small granulomas form multiple series of reaction centers throughout the lymph node. Note the remaining lymphocytes surrounding the granulomas.		File:IPLab3Sarcoidosis3b.jpg\|This is a photomicrograph of the small nodules (arrows) seen in the previous image. Close examination reveals that they are composed of large macrophages (epithelioid macrophages). These small granulomas form multiple series of reaction centers throughout the lymph node. Note the remaining lymphocytes surrounding the granulomas.
	File:IPLab3Sarcoidosis4.jpg\|This photomicrograph of a single granuloma illustrates the individual macrophages (arrows) which make up the bulk of this tissue. There is an absence of necrosis in the center of the lesions in this case.		File:IPLab3Sarcoidosis4.jpg\|This photomicrograph of a single granuloma illustrates the individual macrophages (arrows) which make up the bulk of this tissue. There is an absence of necrosis in the center of the lesions in this case.
	File:~~IPLab3Sarcoidosis5~~.jpg\|This is a photomicrograph of a multinucleated giant cell (1). In the center of this foreign body-containing giant cell there is a small asteroid body (2). There is no functional significance to this asteroid body.		File:IPLab3Sarcoidosis5b.jpg\|This is a photomicrograph of a multinucleated giant cell (1). In the center of this foreign body-containing giant cell there is a small asteroid body (2). There is no functional significance to this asteroid body.
	~~File:IPLab3Sarcoidosis6.jpg\|This is a higher-power photomicrograph of an asteroid body (arrow) inside of a multinucleated giant cell~~.
	</gallery>		</gallery>

Peter Anderson: /* Virtual Microscopy */

2015-09-17T19:27:42Z

Virtual Microscopy

← Older revision		Revision as of 14:27, 17 September 2015
Line 13:		Line 13:

	== Virtual Microscopy ==		== Virtual Microscopy ==
			=== Lymph Node: Sarcoidosis ===
	<peir-vm>IPLab3Sarcoidosis</peir-vm>		<peir-vm>IPLab3Sarcoidosis</peir-vm>

			=== Lymph Node ===
			<peir-vm>UAB-Histology-00035</peir-vm>

	== Study Questions ==		== Study Questions ==

Seung Park at 16:05, 3 January 2014

2014-01-03T16:05:37Z

← Older revision		Revision as of 11:05, 3 January 2014
Line 12:		Line 12:
	</gallery>		</gallery>

	~~Study Questions~~		== Virtual Microscopy ==
			<peir-vm>IPLab3Sarcoidosis</peir-vm>

			== Study Questions ==
	* <spoiler text="What is sarcoidosis?">The exact cause of sarcoidosis is unknown. Sarcoidosis is characterized by non-caseating granulomas in many tissues and organs.</spoiler>		* <spoiler text="What is sarcoidosis?">The exact cause of sarcoidosis is unknown. Sarcoidosis is characterized by non-caseating granulomas in many tissues and organs.</spoiler>
	* <spoiler text="What is the characteristic phenotype of sarcoid granulomas?">The typical characteristic of a sarcoid granuloma is a non-caseating granuloma which consists of an aggregate of tightly-clustered epitheliod cells, often with Langhans’ or multinucleated giant cells. Occasionally, asteroid bodies may be seen.</spoiler>		* <spoiler text="What is the characteristic phenotype of sarcoid granulomas?">The typical characteristic of a sarcoid granuloma is a non-caseating granuloma which consists of an aggregate of tightly-clustered epitheliod cells, often with Langhans’ or multinucleated giant cells. Occasionally, asteroid bodies may be seen.</spoiler>

Seung Park: /* Images */

2013-08-30T01:26:11Z

Images

← Older revision		Revision as of 20:26, 29 August 2013
Line 31:		Line 31:

	=== Images ===		=== Images ===
	* [~~http://peir.path.uab.edu~~/library/index.php?/tags/531-sarcoidosis PEIR Digital Library: Sarcoidosis Images]		* [{{SERVER}}/library/index.php?/tags/531-sarcoidosis PEIR Digital Library: Sarcoidosis Images]
	* [http://library.med.utah.edu/WebPath/LUNGHTML/LUNGIDX.html#2 WebPath: Granulomatous Disease]		* [http://library.med.utah.edu/WebPath/LUNGHTML/LUNGIDX.html#2 WebPath: Granulomatous Disease]

Seung Park: /* Related IPLab Cases */

2013-08-22T02:18:50Z

Related IPLab Cases

← Older revision		Revision as of 21:18, 21 August 2013
Line 34:		Line 34:
	* [http://library.med.utah.edu/WebPath/LUNGHTML/LUNGIDX.html#2 WebPath: Granulomatous Disease]		* [http://library.med.utah.edu/WebPath/LUNGHTML/LUNGIDX.html#2 WebPath: Granulomatous Disease]

	=== Related IPLab Cases ===		== Related IPLab Cases ==
	* [[IPLab:Lab 2:Metastatic Calcification\|Lab 2: Lung: Metastatic Calcification]]		* [[IPLab:Lab 2:Metastatic Calcification\|Lab 2: Lung: Metastatic Calcification]]

	{{IPLab 3}}		{{IPLab 3}}
	[[Category: IPLab:Lab 3]]		[[Category: IPLab:Lab 3]]

Seung Park: /* Related IPLab Cases */

2013-08-19T15:42:34Z

Related IPLab Cases

← Older revision		Revision as of 10:42, 19 August 2013
Line 35:		Line 35:

	=== Related IPLab Cases ===		=== Related IPLab Cases ===
	[[IPLab:Lab 2:Metastatic Calcification\|Lab 2: Lung: Metastatic Calcification]]		* [[IPLab:Lab 2:Metastatic Calcification\|Lab 2: Lung: Metastatic Calcification]]

	{{IPLab 3}}		{{IPLab 3}}
	[[Category: IPLab:Lab 3]]		[[Category: IPLab:Lab 3]]

Seung Park: /* Related IPLab Cases */

2013-08-19T15:42:23Z

Related IPLab Cases

← Older revision		Revision as of 10:42, 19 August 2013
Line 35:		Line 35:

	=== Related IPLab Cases ===		=== Related IPLab Cases ===
			[[IPLab:Lab 2:Metastatic Calcification\|Lab 2: Lung: Metastatic Calcification]]

	{{IPLab 3}}		{{IPLab 3}}
	[[Category: IPLab:Lab 3]]		[[Category: IPLab:Lab 3]]

Seung Park: /* Images */

2013-08-19T15:41:40Z

Images

← Older revision		Revision as of 10:41, 19 August 2013
Line 31:		Line 31:

	=== Images ===		=== Images ===
			* [http://peir.path.uab.edu/library/index.php?/tags/531-sarcoidosis PEIR Digital Library: Sarcoidosis Images]
			* [http://library.med.utah.edu/WebPath/LUNGHTML/LUNGIDX.html#2 WebPath: Granulomatous Disease]

	=== Related IPLab Cases ===		=== Related IPLab Cases ===

Seung Park: /* Journal Articles */

2013-08-19T15:37:51Z

Journal Articles

← Older revision		Revision as of 10:37, 19 August 2013
Line 28:		Line 28:
	=== Journal Articles ===		=== Journal Articles ===
	* English JC, Patel PJ, Greer KE. [http://www.mdconsult.com/das/article/body/421068364-2/jorg=journal&source=MI&sp=11817316&sid=119276088/N/217466/1.html?issn= Sarcoidosis]. ''J Am Acad Dermatol'' 2001;44:725-43		* English JC, Patel PJ, Greer KE. [http://www.mdconsult.com/das/article/body/421068364-2/jorg=journal&source=MI&sp=11817316&sid=119276088/N/217466/1.html?issn= Sarcoidosis]. ''J Am Acad Dermatol'' 2001;44:725-43
			* Johns CJ, Michele TM. [http://www.ncbi.nlm.nih.gov/pubmed/10195091 The clinical management of sarcoidosis. A 50-year experience at the Johns Hopkins Hospital]. ''Medicine (Baltimore)'' 1999 Mar;78(2):65-111.

	=== Images ===		=== Images ===

← Older revision		Revision as of 18:17, 19 June 2020
Line 5:		Line 5:
	<gallery heights="250px" widths="250px">		<gallery heights="250px" widths="250px">
	File:IPLab3Sarcoidosis1.jpg\|This is a low-power photomicrograph of a lymph node. Note the rather pale-pink color of the tissue with dark-staining cells found in only a few scattered areas. These darker cells represent the original lymphocytes of this lymphoid organ.		File:IPLab3Sarcoidosis1.jpg\|This is a low-power photomicrograph of a lymph node. Note the rather pale-pink color of the tissue with dark-staining cells found in only a few scattered areas. These darker cells represent the original lymphocytes of this lymphoid organ.
	File:~~IPLab3Sarcoidosis2~~.jpg\|This photomicrograph of lymph node tissue illustrates a paucity of lymphocytes as well as numerous small, pale-staining nodules (arrows) throughout the tissue.		File:IPLab3Sarcoidosis2b.jpg\|This photomicrograph of lymph node tissue illustrates a paucity of lymphocytes as well as numerous small, pale-staining nodules (arrows) throughout the tissue.
	File:~~IPLab3Sarcoidosis3~~.jpg\|This is a photomicrograph of the small nodules (arrows) seen in the previous image. Close examination reveals that they are composed of large macrophages (epithelioid macrophages). These small granulomas form multiple series of reaction centers throughout the lymph node. Note the remaining lymphocytes surrounding the granulomas.		File:IPLab3Sarcoidosis3b.jpg\|This is a photomicrograph of the small nodules (arrows) seen in the previous image. Close examination reveals that they are composed of large macrophages (epithelioid macrophages). These small granulomas form multiple series of reaction centers throughout the lymph node. Note the remaining lymphocytes surrounding the granulomas.
	File:IPLab3Sarcoidosis4.jpg\|This photomicrograph of a single granuloma illustrates the individual macrophages (arrows) which make up the bulk of this tissue. There is an absence of necrosis in the center of the lesions in this case.		File:IPLab3Sarcoidosis4.jpg\|This photomicrograph of a single granuloma illustrates the individual macrophages (arrows) which make up the bulk of this tissue. There is an absence of necrosis in the center of the lesions in this case.
	File:~~IPLab3Sarcoidosis5~~.jpg\|This is a photomicrograph of a multinucleated giant cell (1). In the center of this foreign body-containing giant cell there is a small asteroid body (2). There is no functional significance to this asteroid body.		File:IPLab3Sarcoidosis5b.jpg\|This is a photomicrograph of a multinucleated giant cell (1). In the center of this foreign body-containing giant cell there is a small asteroid body (2). There is no functional significance to this asteroid body.
	~~File:IPLab3Sarcoidosis6.jpg\|This is a higher-power photomicrograph of an asteroid body (arrow) inside of a multinucleated giant cell~~.
	</gallery>		</gallery>