IPLab:Lab 3:Healed Myocardial Infarction - Revision history

Peter Anderson: /* Images */

2020-06-24T01:36:55Z

‎Images

Peter Anderson: /* Autopsy Findings */

2020-06-24T01:16:40Z

‎Autopsy Findings

Peter Anderson: /* Clinical Summary */

2020-06-24T01:16:27Z

‎Clinical Summary

Seung Park at 16:09, 3 January 2014

2014-01-03T16:09:47Z

Seung Park: /* Images */

2013-08-30T01:28:04Z

‎Images

Seung Park: /* Related IPLab Cases */

2013-08-22T02:19:48Z

‎Related IPLab Cases

Seung Park: /* Journal Articles */

2013-08-21T22:36:19Z

‎Journal Articles

Seung Park: /* Related IPLab Cases */

2013-08-21T22:34:59Z

‎Related IPLab Cases

Seung Park: /* Images */

2013-08-21T22:34:21Z

‎Images

Seung Park: /* Reference */

2013-08-21T22:33:55Z

‎Reference

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 == Images ==
 <gallery heights="250px" widths="250px">
-File:IPLab3HealedMyocardialInfarction1.jpg|This is a gross photograph of a heart with areas of old healed myocardial infarction (scars) outlined by arrows.
+File:IPLab3HealedMyocardialInfarction1b.jpg|This is a gross photograph of a heart with areas of old healed myocardial infarction (scars) outlined by arrows.
-File:IPLab3HealedMyocardialInfarction2.jpg|This is a low-power photomicrograph of a healed myocardial infarction with a fibrous scar. Remaining normal tissue is on the left (1) and the fibrous connective tissue scar is on the right (2).
+File:IPLab3HealedMyocardialInfarction2b.jpg|This is a low-power photomicrograph of a healed myocardial infarction with a fibrous scar. Remaining normal tissue is on the right (1) and the fibrous connective tissue scar is on the left (2).
-File:IPLab3HealedMyocardialInfarction3.jpg|This is a higher-power photomicrograph of a healed myocardial infarction with a fibrous scar. Remaining normal tissue is at the top (1) and the fibrous connective tissue scar is at the bottom (2). Note the presence of occasional hypereosinophilic myocytes indicating recent acute ischemic injury to this region of old scar tissue (arrows).
+File:IPLab3HealedMyocardialInfarction3b.jpg|This is a higher-power photomicrograph of the healed myocardial infarction with a fibrous scar. The normal tissue is on the right (1) and the fibrous connective tissue scar is on the upper left (2).
-File:IPLab3HealedMyocardialInfarction4.jpg|This is another high-power photomicrograph of a healed myocardial infarction. Note the remaining normal myocytes (1), the fibrous connective tissue (2), and occasional hypereosinophilic myocytes indicating recent acute ischemic injury (arrow).
+File:IPLab3HealedMyocardialInfarction4b.jpg|This is a higher-power photomicrograph of a healed myocardial infarction with a fibrous scar. Remaining normal tissue is at the right (1) and the fibrous connective tissue scar is at the left (2). Note the presence of occasional hypereosinophilic myocytes (arrows) indicating recent acute ischemic injury to this region of old scar tissue.
-File:IPLab3HealedMyocardialInfarction5.jpg|This is a low-power photomicrograph of two sections of myocardial tissue stained with a trichrome stain to demonstrate fibrous connective tissue (blue). The section on the left is from a heart with a recent myocardial infarction. Notice the absence of fibrous connective tissue. The section on the right is from a heart with an old healed infarct and it contains extensive fibrous connective tissue scars.
+File:IPLab3HealedMyocardialInfarction5bs.jpg|This is a low-power photomicrograph of myocardial tissue stained with a trichrome stain to demonstrate fibrous connective tissue (blue-green). The section shows the mature fibrous connective tissue  from this heart with an old healed infarct.  Some viable myocardial tissue remains (arrows).
-File:IPLab3HealedMyocardialInfarction6.jpg|This is a photomicrograph of a trichrome-stained section from a heart with an acute myocardial infarction. Note that there is little fibrous connective tissue. It is too early for scar formation to have taken place in this acute lesion.
+File:IPLab3HealedMyocardialInfarction6bs.jpg|This is a photomicrograph of a trichrome-stained section of heart containing an old healed myocardial infarction. The scar is composed of mature fibrous connective tissue (blue-green) and some remaining viable myocytes (red).  A small focus of adipose tissue can be seen in the scar (arrow).
 </gallery>

← Older revision		Revision as of 01:16, 24 June 2020
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	Autopsy showed a 340-gram heart with extensive transmural reddish discoloration of the anterolateral portion of the myocardium of the left ventricle. There was severe atherosclerotic narrowing of all coronary arteries and an acute thrombus in the left anterior descending. The lungs showed pulmonary edema and early bronchopneumonia.		Autopsy showed a 340-gram heart with extensive transmural reddish discoloration of the anterolateral portion of the myocardium of the left ventricle. There was severe atherosclerotic narrowing of all coronary arteries and an acute thrombus in the left anterior descending. The lungs showed pulmonary edema and early bronchopneumonia.
−
−	~~== Autopsy Findings ==~~
−	Autopsy showed a 340-gram heart with extensive transmural reddish discoloration of the anterolateral portion of the myocardium of the left ventricle. There was severe atherosclerotic narrowing of all coronary arteries especially the left anterior descending. The lungs showed pulmonary edema and early bronchopneumonia.

	== Images ==		== Images ==

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 == Clinical Summary ==
-This 37-year-old white female with a 22 year history of insulin-dependent diabetes was admitted to the hospital 10 hours prior to death complaining of chest pain and shortness of breath. Three months before, she had begun to experience progressive weakness and for the previous 3 weeks she noticed increasing dyspnea on exertion and worsening of a chronic cough.
+This 57-year-old white female with a 22 year history of insulin-dependent diabetes was admitted to the hospital 10 hours prior to death complaining of shortness of breath. Three months before, she had begun to experience progressive weakness and for the previous 3 weeks she noticed increasing dyspnea on exertion and worsening of a chronic cough.  Despite appropriate care she developed an intractable arrhythmia and could not be resuscitated.
 == Autopsy Findings ==

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 File:IPLab3HealedMyocardialInfarction8.jpg|This is a higher-power photomicrograph of a trichrome-stained section of heart containing an old healed MI. The scar tissue (mature fibrous connective tissue) is stained blue.
 </gallery>
 == Study Questions ==

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 === Images ===
-* [http://peir.path.uab.edu/library/index.php?/tags/43-myocardial_infarct PEIR Digital Library: Myocardial Infarct Images]
+* [{{SERVER}}/library/index.php?/tags/43-myocardial_infarct PEIR Digital Library: Myocardial Infarct Images]
 * [http://library.med.utah.edu/WebPath/CVHTML/CVIDX.html WebPath: Cardiovascular Pathology]

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 * [http://library.med.utah.edu/WebPath/CVHTML/CVIDX.html WebPath: Cardiovascular Pathology]
-=== Related IPLab Cases ===
+== Related IPLab Cases ==
 * [[IPLab:Lab 1:Myocardial Infarction|Lab 1: Heart: Myocardial Infarction (Coagulative Necrosis)]]
 * [[IPLab:Lab 3:Acute Myocardial Infarction|Lab 3: Heart: Acute Myocardial Infarction]]

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 === Journal Articles ===
+* Yuan S, Liu Y, Zhu L.  [http://www.ncbi.nlm.nih.gov/pubmed/10626065 Vascular complications of diabetes mellitus].  ''Clin Exp Pharmacol Physiol'' 1999 Dec;26(12):977-8.
 === Images ===

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 === Related IPLab Cases ===
+* [[IPLab:Lab 1:Myocardial Infarction|Lab 1: Heart: Myocardial Infarction (Coagulative Necrosis)]]
 {{IPLab 3}}
 [[Category: IPLab:Lab 3]]

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 == Additional Resources ==
 === Reference ===
+* [http://emedicine.medscape.com/article/155919-overview eMedicine Medical Library: Myocardial Infarction]
 === Journal Articles ===