IPLab:Lab 3:Bronchopneumonia - Revision history

Peter Anderson: /* Images */

2020-06-19T23:07:31Z

Images

← Older revision		Revision as of 18:07, 19 June 2020
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	File:IPLab3Bronchopneumonia3.jpg\|This is a low-power photomicrograph of lung with multiple focal lesions (1) throughout the tissue, some of which have a pale center indicating a loss of parenchymal tissue (2). This is typical of abscess formation in the lung and represents a form of liquefaction necrosis. This pneumonia is bronchopneumonia since the distribution is along the bronchi and the terminal airway distribution throughout the lung. Note that there are some areas of lung which appear relatively normal, having a pale-staining appearance. Other areas, such as in the lower central area (3), are much darker, indicating a heavy cellular infiltrate.		File:IPLab3Bronchopneumonia3.jpg\|This is a low-power photomicrograph of lung with multiple focal lesions (1) throughout the tissue, some of which have a pale center indicating a loss of parenchymal tissue (2). This is typical of abscess formation in the lung and represents a form of liquefaction necrosis. This pneumonia is bronchopneumonia since the distribution is along the bronchi and the terminal airway distribution throughout the lung. Note that there are some areas of lung which appear relatively normal, having a pale-staining appearance. Other areas, such as in the lower central area (3), are much darker, indicating a heavy cellular infiltrate.
	File:IPLab3Bronchopneumonia4.jpg\|This photomicrograph of the wall of an abscess (1) illustrates liquefaction necrosis in the center of the abscess (2). The remaining lung parenchyma (on the right side of the image) has extensive neutrophilic infiltration into the alveoli (3). This abscess has destroyed a portion of the lung, but other areas of the lung where the normal structure has been retained could recover normal function.		File:IPLab3Bronchopneumonia4.jpg\|This photomicrograph of the wall of an abscess (1) illustrates liquefaction necrosis in the center of the abscess (2). The remaining lung parenchyma (on the right side of the image) has extensive neutrophilic infiltration into the alveoli (3). This abscess has destroyed a portion of the lung, but other areas of the lung where the normal structure has been retained could recover normal function.
	File:~~IPLab3Bronchopneumonia5~~.jpg\|This is a photomicrograph of lung tissue affected by bronchopneumonia. Note that the alveolar structure of this tissue, which is in the region of a terminal bronchiole (1), has been retained despite the massive infiltration of inflammatory cells. These inflammatory cells are primarily neutrophils.		File:IPLab3Bronchopneumonia5b.jpg\|This is a photomicrograph of lung tissue affected by bronchopneumonia. Note that the alveolar structure of this tissue, which is in the region of a terminal bronchiole (1), has been retained despite the massive infiltration of inflammatory cells. These inflammatory cells are primarily neutrophils.
	File:~~IPLab3Bronchopneumonia6~~.jpg\|This is a photomicrograph of another area in the lung showing a terminal bronchiole (1) in which the mucosal lining has been almost completely destroyed. There is extensive neutrophilic infiltration throughout this lung tissue.		File:IPLab3Bronchopneumonia6b.jpg\|This is a photomicrograph of another area in the lung showing a terminal bronchiole (1) in which the mucosal lining has been almost completely destroyed. There is extensive neutrophilic infiltration throughout this lung tissue.
	File:IPLab3Bronchopneumonia7.jpg\|This higher-power photomicrograph shows a central portion of an abscess. Note the absence of any parenchymal lung tissue in this section due to extensive neutrophilic infiltration with liquefaction necrosis of the parenchymal tissue. Masses of leukocytes (primarily neutrophils), fluid ("liquor puris" which is serum, fibrin, etc.), and necrotic debris within an abscess form what is referred to as "purulent material" -- or "pus" in lay terminology. The blue-staining mass in the center of this abscess (arrow) represents colonies of bacteria.		File:IPLab3Bronchopneumonia7.jpg\|This higher-power photomicrograph shows a central portion of an abscess. Note the absence of any parenchymal lung tissue in this section due to extensive neutrophilic infiltration with liquefaction necrosis of the parenchymal tissue. Masses of leukocytes (primarily neutrophils), fluid ("liquor puris" which is serum, fibrin, etc.), and necrotic debris within an abscess form what is referred to as "purulent material" -- or "pus" in lay terminology. The blue-staining mass in the center of this abscess (arrow) represents colonies of bacteria.
	</gallery>		</gallery>

Peter Anderson: /* Clinical Summary */

2020-06-19T23:04:26Z

Clinical Summary

← Older revision		Revision as of 18:04, 19 June 2020
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	== Clinical Summary ==		== Clinical Summary ==
	This 15-year-old black female sustained third degree burns involving approximately 85% of the body surface. On admission to the hospital, the patient was taken to the operating room where a tracheotomy was performed and her burned body surface was debrided. After a few days of hospitalization, the peripheral white blood count was 41,000 cells/mm³ with a shift to the left. In spite of intensive therapy, which included administration of fluids and antibiotics, the patient expired on the sixth hospital day.		This 15-year-old black female sustained third degree burns involving approximately 85% of the body surface. On admission to the hospital, the patient was taken to the operating room where a tracheotomy was performed and her burned body surface was debrided. After a few days of hospitalization, the peripheral white blood count was 41,000 cells/mm³ with a shift to the left. In spite of intensive therapy, which included administration of fluids and antibiotics, the patient expired on the sixth hospital day.

			At autopsy each lung weighed approximately 630 grams and was studded with gray nodules which ranged in size from 3 to 6 mm in diameter. In several areas, these coalesced to form nodules having necrotic-appearing centers.

	== Images ==		== Images ==

Peter Anderson: /* Autopsy Findings */

2020-06-19T23:03:55Z

Autopsy Findings

← Older revision		Revision as of 18:03, 19 June 2020
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	== Clinical Summary ==		== Clinical Summary ==
	This 15-year-old black female sustained third degree burns involving approximately 85% of the body surface. On admission to the hospital, the patient was taken to the operating room where a tracheotomy was performed and her burned body surface was debrided. After a few days of hospitalization, the peripheral white blood count was 41,000 cells/mm³ with a shift to the left. In spite of intensive therapy, which included administration of fluids and antibiotics, the patient expired on the sixth hospital day.		This 15-year-old black female sustained third degree burns involving approximately 85% of the body surface. On admission to the hospital, the patient was taken to the operating room where a tracheotomy was performed and her burned body surface was debrided. After a few days of hospitalization, the peripheral white blood count was 41,000 cells/mm³ with a shift to the left. In spite of intensive therapy, which included administration of fluids and antibiotics, the patient expired on the sixth hospital day.

	~~== Autopsy Findings ==~~
	Each lung weighed approximately 630 grams and was studded with gray nodules which ranged in size from 3 to 6 mm in diameter. In several areas, these coalesced to form nodules having necrotic-appearing centers.


	== Images ==		== Images ==

Peter Anderson: /* Virtual Microscopy */

2015-09-16T19:29:49Z

Virtual Microscopy

← Older revision		Revision as of 14:29, 16 September 2015
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	== Virtual Microscopy ==		== Virtual Microscopy ==
			=== Lung: Bronchopneumonia ===
	<peir-vm>IPLab3Bronchopneumonia</peir-vm>		<peir-vm>IPLab3Bronchopneumonia</peir-vm>

			=== Normal Lung ===
			<peir-vm>UAB-Histology-00107</peir-vm>

	== Study Questions ==		== Study Questions ==

Seung Park at 16:05, 3 January 2014

2014-01-03T16:05:12Z

← Older revision		Revision as of 11:05, 3 January 2014
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	</gallery>		</gallery>

	~~Study Questions~~		== Virtual Microscopy ==
			<peir-vm>IPLab3Bronchopneumonia</peir-vm>

			== Study Questions ==
	* <spoiler text="What does it mean to have a shift to the left?">A "shift to the left" indicates an increased ratio of immature PMNs ("bands") to mature PMNs ("segs") within the peripheral circulation.</spoiler>		* <spoiler text="What does it mean to have a shift to the left?">A "shift to the left" indicates an increased ratio of immature PMNs ("bands") to mature PMNs ("segs") within the peripheral circulation.</spoiler>
	* <spoiler text="Is there destruction of lung parenchyma in bronchopneumonia?">Yes, there is usually destruction of alveoli and, in this case, there are abscesses containing bacteria.</spoiler>		* <spoiler text="Is there destruction of lung parenchyma in bronchopneumonia?">Yes, there is usually destruction of alveoli and, in this case, there are abscesses containing bacteria.</spoiler>

Seung Park: /* Images */

2013-08-30T01:25:58Z

Images

← Older revision		Revision as of 20:25, 29 August 2013
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	=== Images ===		=== Images ===
	* [~~http://peir.path.uab.edu~~/library/index.php?/tags/316-bronchopneumonia PEIR Digital Library: Bronchopneumonia Images]		* [{{SERVER}}/library/index.php?/tags/316-bronchopneumonia PEIR Digital Library: Bronchopneumonia Images]
	* [http://library.med.utah.edu/WebPath/LUNGHTML/LUNGIDX.html#1 WebPath: Pneumonias]		* [http://library.med.utah.edu/WebPath/LUNGHTML/LUNGIDX.html#1 WebPath: Pneumonias]

Seung Park: /* Related IPLab Cases */

2013-08-22T02:18:41Z

Related IPLab Cases

← Older revision		Revision as of 21:18, 21 August 2013
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	* [http://library.med.utah.edu/WebPath/LUNGHTML/LUNGIDX.html#1 WebPath: Pneumonias]		* [http://library.med.utah.edu/WebPath/LUNGHTML/LUNGIDX.html#1 WebPath: Pneumonias]

	=== Related IPLab Cases ===		== Related IPLab Cases ==
	* [[IPLab:Lab 3:Lobar Pneumonia\|Lab 3: Lung: Lobar Pneumonia]]		* [[IPLab:Lab 3:Lobar Pneumonia\|Lab 3: Lung: Lobar Pneumonia]]

Seung Park at 13:29, 19 August 2013

2013-08-19T13:29:44Z

← Older revision		Revision as of 08:29, 19 August 2013
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	=== Images ===		=== Images ===
			* [http://peir.path.uab.edu/library/index.php?/tags/316-bronchopneumonia PEIR Digital Library: Bronchopneumonia Images]
			* [http://library.med.utah.edu/WebPath/LUNGHTML/LUNGIDX.html#1 WebPath: Pneumonias]

			=== Related IPLab Cases ===
			* [[IPLab:Lab 3:Lobar Pneumonia\|Lab 3: Lung: Lobar Pneumonia]]

	~~=== Related IPLab Cases ===~~

	{{IPLab 3}}		{{IPLab 3}}
	[[Category: IPLab:Lab 3]]		[[Category: IPLab:Lab 3]]

Seung Park at 13:27, 19 August 2013

2013-08-19T13:27:47Z

← Older revision		Revision as of 08:27, 19 August 2013
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	=== Journal Articles ===		=== Journal Articles ===
			* Katz DS, Leung AN. [http://www.ncbi.nlm.nih.gov/pubmed/10516903 Radiology of pneumonia]. ''Clin Chest Med'' 1999 Sep;20(3):549-62.

	=== Images ===		=== Images ===

Seung Park at 13:26, 19 August 2013

2013-08-19T13:26:42Z

← Older revision		Revision as of 08:26, 19 August 2013
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	== Additional Resources ==		== Additional Resources ==
	=== Reference ===		=== Reference ===
			* [http://emedicine.medscape.com/article/807499-overview eMedicine Medical Library: Empyema and Abscess Pneumonia]
			* [http://emedicine.medscape.com/article/296198-overview eMedicine Medical Library: Aspiration Pneumonia]
			* [http://emedicine.medscape.com/article/300157-overview eMedicine Medical Library: Bacterial Pneumonia]
			* [http://www.merckmanuals.com/professional/pulmonary_disorders/pneumonia/overview_of_pneumonia.html Merck Manual: Overview of Pneumonia]

	=== Journal Articles ===		=== Journal Articles ===

← Older revision		Revision as of 18:07, 19 June 2020
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	File:IPLab3Bronchopneumonia3.jpg\|This is a low-power photomicrograph of lung with multiple focal lesions (1) throughout the tissue, some of which have a pale center indicating a loss of parenchymal tissue (2). This is typical of abscess formation in the lung and represents a form of liquefaction necrosis. This pneumonia is bronchopneumonia since the distribution is along the bronchi and the terminal airway distribution throughout the lung. Note that there are some areas of lung which appear relatively normal, having a pale-staining appearance. Other areas, such as in the lower central area (3), are much darker, indicating a heavy cellular infiltrate.		File:IPLab3Bronchopneumonia3.jpg\|This is a low-power photomicrograph of lung with multiple focal lesions (1) throughout the tissue, some of which have a pale center indicating a loss of parenchymal tissue (2). This is typical of abscess formation in the lung and represents a form of liquefaction necrosis. This pneumonia is bronchopneumonia since the distribution is along the bronchi and the terminal airway distribution throughout the lung. Note that there are some areas of lung which appear relatively normal, having a pale-staining appearance. Other areas, such as in the lower central area (3), are much darker, indicating a heavy cellular infiltrate.
	File:IPLab3Bronchopneumonia4.jpg\|This photomicrograph of the wall of an abscess (1) illustrates liquefaction necrosis in the center of the abscess (2). The remaining lung parenchyma (on the right side of the image) has extensive neutrophilic infiltration into the alveoli (3). This abscess has destroyed a portion of the lung, but other areas of the lung where the normal structure has been retained could recover normal function.		File:IPLab3Bronchopneumonia4.jpg\|This photomicrograph of the wall of an abscess (1) illustrates liquefaction necrosis in the center of the abscess (2). The remaining lung parenchyma (on the right side of the image) has extensive neutrophilic infiltration into the alveoli (3). This abscess has destroyed a portion of the lung, but other areas of the lung where the normal structure has been retained could recover normal function.
	File:~~IPLab3Bronchopneumonia5~~.jpg\|This is a photomicrograph of lung tissue affected by bronchopneumonia. Note that the alveolar structure of this tissue, which is in the region of a terminal bronchiole (1), has been retained despite the massive infiltration of inflammatory cells. These inflammatory cells are primarily neutrophils.		File:IPLab3Bronchopneumonia5b.jpg\|This is a photomicrograph of lung tissue affected by bronchopneumonia. Note that the alveolar structure of this tissue, which is in the region of a terminal bronchiole (1), has been retained despite the massive infiltration of inflammatory cells. These inflammatory cells are primarily neutrophils.
	File:~~IPLab3Bronchopneumonia6~~.jpg\|This is a photomicrograph of another area in the lung showing a terminal bronchiole (1) in which the mucosal lining has been almost completely destroyed. There is extensive neutrophilic infiltration throughout this lung tissue.		File:IPLab3Bronchopneumonia6b.jpg\|This is a photomicrograph of another area in the lung showing a terminal bronchiole (1) in which the mucosal lining has been almost completely destroyed. There is extensive neutrophilic infiltration throughout this lung tissue.
	File:IPLab3Bronchopneumonia7.jpg\|This higher-power photomicrograph shows a central portion of an abscess. Note the absence of any parenchymal lung tissue in this section due to extensive neutrophilic infiltration with liquefaction necrosis of the parenchymal tissue. Masses of leukocytes (primarily neutrophils), fluid ("liquor puris" which is serum, fibrin, etc.), and necrotic debris within an abscess form what is referred to as "purulent material" -- or "pus" in lay terminology. The blue-staining mass in the center of this abscess (arrow) represents colonies of bacteria.		File:IPLab3Bronchopneumonia7.jpg\|This higher-power photomicrograph shows a central portion of an abscess. Note the absence of any parenchymal lung tissue in this section due to extensive neutrophilic infiltration with liquefaction necrosis of the parenchymal tissue. Masses of leukocytes (primarily neutrophils), fluid ("liquor puris" which is serum, fibrin, etc.), and necrotic debris within an abscess form what is referred to as "purulent material" -- or "pus" in lay terminology. The blue-staining mass in the center of this abscess (arrow) represents colonies of bacteria.
	</gallery>		</gallery>