IPLab:Lab 3:Bronchopneumonia - Revision history

Peter Anderson: /* Images */

2020-06-19T23:07:31Z

‎Images

Peter Anderson: /* Clinical Summary */

2020-06-19T23:04:26Z

‎Clinical Summary

Peter Anderson: /* Autopsy Findings */

2020-06-19T23:03:55Z

‎Autopsy Findings

Peter Anderson: /* Virtual Microscopy */

2015-09-16T19:29:49Z

‎Virtual Microscopy

Seung Park at 16:05, 3 January 2014

2014-01-03T16:05:12Z

Seung Park: /* Images */

2013-08-30T01:25:58Z

‎Images

Seung Park: /* Related IPLab Cases */

2013-08-22T02:18:41Z

‎Related IPLab Cases

Seung Park at 13:29, 19 August 2013

2013-08-19T13:29:44Z

Seung Park at 13:27, 19 August 2013

2013-08-19T13:27:47Z

Seung Park at 13:26, 19 August 2013

2013-08-19T13:26:42Z

@@ Line 10: / Line 10: @@
 File:IPLab3Bronchopneumonia3.jpg|This is a low-power photomicrograph of lung with multiple focal lesions (1) throughout the tissue, some of which have a pale center indicating a loss of parenchymal tissue (2). This is typical of abscess formation in the lung and represents a form of liquefaction necrosis. This pneumonia is bronchopneumonia since the distribution is along the bronchi and the terminal airway distribution throughout the lung. Note that there are some areas of lung which appear relatively normal, having a pale-staining appearance. Other areas, such as in the lower central area (3), are much darker, indicating a heavy cellular infiltrate.
 File:IPLab3Bronchopneumonia4.jpg|This photomicrograph of the wall of an abscess (1) illustrates liquefaction necrosis in the center of the abscess (2). The remaining lung parenchyma (on the right side of the image) has extensive neutrophilic infiltration into the alveoli (3). This abscess has destroyed a portion of the lung, but other areas of the lung where the normal structure has been retained could recover normal function.
-File:IPLab3Bronchopneumonia5.jpg|This is a photomicrograph of lung tissue affected by bronchopneumonia. Note that the alveolar structure of this tissue, which is in the region of a terminal bronchiole (1), has been retained despite the massive infiltration of inflammatory cells. These inflammatory cells are primarily neutrophils.
+File:IPLab3Bronchopneumonia5b.jpg|This is a photomicrograph of lung tissue affected by bronchopneumonia. Note that the alveolar structure of this tissue, which is in the region of a terminal bronchiole (1), has been retained despite the massive infiltration of inflammatory cells. These inflammatory cells are primarily neutrophils.
-File:IPLab3Bronchopneumonia6.jpg|This is a photomicrograph of another area in the lung showing a terminal bronchiole (1) in which the mucosal lining has been almost completely destroyed. There is extensive neutrophilic infiltration throughout this lung tissue.
+File:IPLab3Bronchopneumonia6b.jpg|This is a photomicrograph of another area in the lung showing a terminal bronchiole (1) in which the mucosal lining has been almost completely destroyed. There is extensive neutrophilic infiltration throughout this lung tissue.
 File:IPLab3Bronchopneumonia7.jpg|This higher-power photomicrograph shows a central portion of an abscess. Note the absence of any parenchymal lung tissue in this section due to extensive neutrophilic infiltration with liquefaction necrosis of the parenchymal tissue. Masses of leukocytes (primarily neutrophils), fluid ("liquor puris" which is serum, fibrin, etc.), and necrotic debris within an abscess form what is referred to as "purulent material" -- or "pus" in lay terminology. The blue-staining mass in the center of this abscess (arrow) represents colonies of bacteria.
 </gallery>

@@ Line 1: / Line 1: @@
 == Clinical Summary ==
 This 15-year-old black female sustained third degree burns involving approximately 85% of the body surface. On admission to the hospital, the patient was taken to the operating room where a tracheotomy was performed and her burned body surface was debrided. After a few days of hospitalization, the peripheral white blood count was 41,000 cells/mm³ with a shift to the left. In spite of intensive therapy, which included administration of fluids and antibiotics, the patient expired on the sixth hospital day.
 == Images ==

@@ Line 1: / Line 1: @@
 == Clinical Summary ==
 This 15-year-old black female sustained third degree burns involving approximately 85% of the body surface. On admission to the hospital, the patient was taken to the operating room where a tracheotomy was performed and her burned body surface was debrided. After a few days of hospitalization, the peripheral white blood count was 41,000 cells/mm³ with a shift to the left. In spite of intensive therapy, which included administration of fluids and antibiotics, the patient expired on the sixth hospital day.
 == Images ==

@@ Line 18: / Line 18: @@
 == Virtual Microscopy ==
 <peir-vm>IPLab3Bronchopneumonia</peir-vm>
 == Study Questions ==

@@ Line 17: / Line 17: @@
 </gallery>
-Study Questions
+== Virtual Microscopy ==
 * <spoiler text="What does it mean to have a shift to the left?">A "shift to the left" indicates an increased ratio of immature PMNs ("bands") to mature PMNs ("segs") within the peripheral circulation.</spoiler>
 * <spoiler text="Is there destruction of lung parenchyma in bronchopneumonia?">Yes, there is usually destruction of alveoli and, in this case, there are abscesses containing bacteria.</spoiler>

@@ Line 34: / Line 34: @@
 === Images ===
-* [http://peir.path.uab.edu/library/index.php?/tags/316-bronchopneumonia PEIR Digital Library: Bronchopneumonia Images]
+* [{{SERVER}}/library/index.php?/tags/316-bronchopneumonia PEIR Digital Library: Bronchopneumonia Images]
 * [http://library.med.utah.edu/WebPath/LUNGHTML/LUNGIDX.html#1 WebPath: Pneumonias]

@@ Line 37: / Line 37: @@
 * [http://library.med.utah.edu/WebPath/LUNGHTML/LUNGIDX.html#1 WebPath: Pneumonias]
-=== Related IPLab Cases ===
+== Related IPLab Cases ==
 * [[IPLab:Lab 3:Lobar Pneumonia|Lab 3: Lung: Lobar Pneumonia]]

@@ Line 31: / Line 31: @@
 === Journal Articles ===
+* Katz DS, Leung AN.  [http://www.ncbi.nlm.nih.gov/pubmed/10516903 Radiology of pneumonia].  ''Clin Chest Med'' 1999 Sep;20(3):549-62.
 === Images ===

@@ Line 25: / Line 25: @@
 == Additional Resources ==
 === Reference ===
+* [http://emedicine.medscape.com/article/807499-overview eMedicine Medical Library: Empyema and Abscess Pneumonia]
 === Journal Articles ===