IPLab:Lab 2:Metastatic Calcification - Revision history

Peter Anderson: /* Autopsy Findings */

2020-06-19T20:10:38Z

‎Autopsy Findings

Peter Anderson: /* Clinical Summary */

2020-06-19T20:10:26Z

‎Clinical Summary

Peter Anderson: /* Virtual Microscopy */

2015-09-16T19:13:35Z

‎Virtual Microscopy

Seung Park at 16:02, 3 January 2014

2014-01-03T16:02:47Z

Seung Park: /* Images */

2013-08-30T01:24:54Z

‎Images

Seung Park at 17:06, 21 August 2013

2013-08-21T17:06:25Z

Peter Anderson at 15:06, 21 August 2013

2013-08-21T15:06:05Z

Seung Park at 06:08, 21 August 2013

2013-08-21T06:08:40Z

Peter Anderson: Created page with "== Images == File:IPLab2Calcification1.jpg|This is a gross photograph of the cut section of the patient's lung showing evidence of sev..."

2013-08-19T16:36:47Z

Created page with "== Images == <gallery heights="250px" widths="250px"> File:IPLab2Calcification1.jpg|This is a gross photograph of the cut section of the patient's lung showing evidence of sev..."

New page

== Images ==
<gallery heights="250px" widths="250px">
File:IPLab2Calcification1.jpg|This is a gross photograph of the cut section of the patient's lung showing evidence of severe metastatic calcification. The lung tissue has a rough, firm appearance with open airways.
File:IPLab2Calcification2.jpg|This low-power photomicrograph of the patient's lung illustrates large, open alveolar spaces. The pleural surface is the curved surface at the top.
File:IPLab2Calcification3.jpg|A higher-power photomicrograph shows a blood vessel cut in longitudinal section (1). Several of the alveoli are filled with a pink-staining proteinaceous fluid (2) indicative of pulmonary edema. The alveolar septa and the wall of the blood vessel have a purplish color due to massive deposition of mineral (primarily calcium) in these tissues (3).
File:IPLab2Calcification4.jpg|This high-power photomicrograph of a blood vessel shows calcium deposits in the vascular wall (1) and proteinaceous material (2) (from edema) within some of the alveoli. The smooth muscle in the vessel wall has been almost completely replaced by calcium deposits.
File:IPLab2Calcification5.jpg|This photomicrograph demonstrates pulmonary alveoli with extensive calcium depositions (1) in the septa and protein accumulations (2) in the alveoli.
File:IPLab2Calcification6.jpg|Metastatic calcification is only one of two forms of pathologic calcification. Unlike metastatic calcification, dystrophic calcification does not require an increase in serum calcium levels. This is a gross specimen of a heart with dystrophic calcification of the aortic valve (arrow).
File:IPLab2Calcification7.jpg|A closer view of this same aortic valve (arrow) illustrates the nodularity and thickening of this valve. This valve would be extremely stiff and almost entirely immobile. This particular example of dystrophic calcification is associated with a degenerative change of the aortic valve due to an unknown cause.
File:IPLab2Calcification8.jpg|This gross photograph affords a closer view of the same aortic valve. Note the nodularity and thickening of this valve due to fibrosis and dystrophic calcification.

</gallery>

{{IPLab 2}}

[[Category: IPLab:Lab 2]]

← Older revision		Revision as of 20:10, 19 June 2020
Line 3:		Line 3:

	In addition to the metastatic breast cancer, important gross findings at autopsy included lungs that were gritty and firm and which weighed 1330 grams. The patient's parathyroid glands were normal.		In addition to the metastatic breast cancer, important gross findings at autopsy included lungs that were gritty and firm and which weighed 1330 grams. The patient's parathyroid glands were normal.
−
−	~~== Autopsy Findings ==~~
−	In addition to the metastatic breast cancer, important gross findings at autopsy included lungs that were gritty and firm and which weighed 1330 grams. The patient's parathyroid glands were normal (two parathyroid hormone assays during life were normal).

	== Images ==		== Images ==

@@ Line 1: / Line 1: @@
 == Clinical Summary ==
-This 47-year-old woman diagnosed with metastatic carcinoma of the breast was also found to have severe hypercalcemia. She developed metastatic calcification which was most prominent in the kidneys and lungs.
+This 47-year-old woman diagnosed with metastatic carcinoma of the breast was also found to have severe hypercalcemia. She developed metastatic calcification which was most prominent in the kidneys and lungs.  The patient was provided hospice care and died of respiratory failure.
 == Autopsy Findings ==

@@ Line 18: / Line 18: @@
 == Virtual Microscopy ==
 <peir-vm>IPLab2Calcification</peir-vm>
 == Study Questions ==

@@ Line 39: / Line 39: @@
 === Images ===
-* [http://peir.path.uab.edu/library/index.php?/tags/1450-metastatic_calcification PEIR Digital Library: Metastatic Calcification Images]
+* [{{SERVER}}/library/index.php?/tags/1450-metastatic_calcification PEIR Digital Library: Metastatic Calcification Images]
 * [http://library.med.utah.edu/WebPath/LUNGHTML/LUNGIDX.html WebPath: Pulmonary Pathology]

← Older revision		Revision as of 06:08, 21 August 2013
Line 1:		Line 1:
		+	== Clinical Summary ==
		+	This 47-year-old woman diagnosed with metastatic carcinoma of the breast was also found to have severe hypercalcemia. She developed metastatic calcification which was most prominent in the kidneys and lungs.
		+
		+	== Autopsy Findings ==
		+	In addition to the metastatic breast cancer, important gross findings at autopsy included lungs that were gritty and firm and which weighed 1330 grams. The patient's parathyroid glands were normal (two parathyroid hormone assays during life were normal).
		+
	== Images ==		== Images ==
	<gallery heights="250px" widths="250px">		<gallery heights="250px" widths="250px">

@@ Line 16: / Line 16: @@
 File:IPLab2Calcification8.jpg|This gross photograph affords a closer view of the same aortic valve. Note the nodularity and thickening of this valve due to fibrosis and dystrophic calcification.
 </gallery>
 == Study Questions ==

@@ Line 28: / Line 28: @@
 * Hypercalcemia of malignancy</spoiler>
 {{IPLab 2}}
 [[Category: IPLab:Lab 2]]