IPLab:Lab 12:Burns - Revision history

Peter Anderson: /* Autopsy Findings */

2020-07-09T21:14:27Z

‎Autopsy Findings

Peter Anderson: /* Clinical Summary */

2020-07-09T21:14:18Z

‎Clinical Summary

Peter Anderson: /* Journal Articles */

2016-08-04T13:06:28Z

‎Journal Articles

Peter Anderson: /* Study Questions */

2015-11-20T15:45:36Z

‎Study Questions

Peter Anderson: /* Study Questions */

2015-11-20T15:44:05Z

‎Study Questions

Seung Park: /* Images */

2013-08-30T01:48:48Z

‎Images

Seung Park: /* Related IPLab Cases */

2013-08-26T15:19:56Z

‎Related IPLab Cases

Seung Park: /* Images */

2013-08-26T15:19:47Z

‎Images

Seung Park: /* Journal Articles */

2013-08-26T15:18:18Z

‎Journal Articles

Seung Park: /* Reference */

2013-08-26T15:17:43Z

‎Reference

← Older revision		Revision as of 21:14, 9 July 2020
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	Carbonaceous material was noted in the throat and posterior pharynx as well as in the trachea and main stem bronchi. The liver was soft, yellow and greasy. Results of premortem blood work showed an elevated blood alcohol level.		Carbonaceous material was noted in the throat and posterior pharynx as well as in the trachea and main stem bronchi. The liver was soft, yellow and greasy. Results of premortem blood work showed an elevated blood alcohol level.
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−	~~== Autopsy Findings ==~~
−	The degree and severity of body surface burns were documented. Carbonaceous material was noted in the throat and posterior pharynx as well as in the trachea and main stem bronchi. The liver was soft, yellow and greasy. Results of premortem blood work showed a blood alcohol level of 147 mg/dL.

	== Images ==		== Images ==

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 == Clinical Summary ==
-This 45-year-old back female was involved in a house fire which killed her husband. Upon admission to a local emergency room she was found to have approximately 80% body surface area burns including 1st, 2nd, and 3rd degree burns. Burns were most severe around the head and neck. The patient was intubated and transferred to a tertiary care center. Upon arrival, the patient had a blood pressure of 71/25 mmHg, a heart rate of 121, and was responsive to deep pain but had few spontaneous movements. Both eyes were swollen shut, her nasal hairs were singed, and carbonaceous deposits were present in her nares, throat, and posterior pharynx. Despite aggressive fluid resuscitation and ventilatory support, she remained hypotensive, and became progressively hypoxemic and hypercapnic until she died approximately eight hours after the fire.
+This 45-year-old female was involved in a house fire which killed her husband. The patient had approximately 80% body surface area burns including 1st, 2nd, and 3rd degree burns. The patient was intubated and given aggressive fluid resuscitation and ventilatory support, but she remained hypotensive and became progressively hypoxemic and hypercapnic until she died approximately eight hours after the fire.
 == Autopsy Findings ==

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 === Journal Articles ===
 * Fukuzuka K, Rosenberg JJ, Gaines GC, Edwards CK 3rd, Clare-Salzler M, MacKay SL, Moldawer LL, Copeland EM 3rd, Mozingo DW.  [http://www.ncbi.nlm.nih.gov/pubmed/10363899 Caspase-3-dependent organ apoptosis early after burn injury].  ''Ann Surg'' 1999 Jun;229(6):851-8; discussion 858-9.
 === Images ===

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 == Study Questions ==
-* <spoiler text="What was the immediate cause of death (COD) in this patient? What other factors played a role in this patient's demise?">This patient died of thermal injury involving 80% body surface area. This large body surface area of burn injury is very severe and has a poor prognosis. The gross and microscopic evidence of smoke inhalation and burn injury to the nose, throat and lungs are indicative of severe lung injury. Inhalation injury is seen in over 80% of patients with a burn size of 85% or more of the total body surface area. Carbon monoxide poisoning also contributes to the early death in inhalation injury.  The manner of death in this case would have been accidental - unless someone deliberately set the fire.
+* <spoiler text="What was the immediate cause of death (COD) in this patient? What other factors played a role in this patient's demise?">The immediate cause of death for this patient is thermal injury involving 80% body surface area. This large body surface area of burn injury is very severe and has a poor prognosis. The gross and microscopic evidence of smoke inhalation and burn injury to the nose, throat and lungs are indicative of severe lung injury. Inhalation injury is seen in over 80% of patients with a burn size of 85% or more of the total body surface area. Carbon monoxide poisoning also contributes to the early death in inhalation injury.  The manner of death in this case would have been accidental - unless someone deliberately set the fire.
 This additional factor of the severity and the extent of the body surface area burn would likely have lead to death of this patient. Clinical management of a patient with burns this severe would be very difficult. Shock and sepsis are common problems in these patients.</spoiler>

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 == Study Questions ==
-* <spoiler text="What was the proximate cause of death in this patient? What other factors played a role in this patient's demise?">This patient died of respiratory failure. The gross and microscopic evidence of smoke inhalation and burn injury to the nose, throat and lungs are indicative of severe lung injury. Inhalation injury is seen in over 80% of patients with a burn size of 85% or more of the total body surface area. Carbon monoxide poisoning also contributes to the early death in inhalation injury.
+* <spoiler text="What was the immediate cause of death (COD) in this patient? What other factors played a role in this patient's demise?">This patient died of thermal injury involving 80% body surface area. This large body surface area of burn injury is very severe and has a poor prognosis. The gross and microscopic evidence of smoke inhalation and burn injury to the nose, throat and lungs are indicative of severe lung injury. Inhalation injury is seen in over 80% of patients with a burn size of 85% or more of the total body surface area. Carbon monoxide poisoning also contributes to the early death in inhalation injury.  The manner of death in this case would have been accidental - unless someone deliberately set the fire.
-An additional factor that likely would have lead to death of this patient was the severity and the extent of the body surface area that was burned. Clinical management of a patient with burns this severe would be very difficult. Shock and sepsis are common problems in these patients.</spoiler>
+This additional factor of the severity and the extent of the body surface area burn would likely have lead to death of this patient. Clinical management of a patient with burns this severe would be very difficult. Shock and sepsis are common problems in these patients.</spoiler>
 * <spoiler text="What is the significance of the fatty liver and the blood alcohol level noted in this patient?">The fatty liver and the elevated blood alcohol level indicate that this patient was severely incapacitated by alcohol prior to the fire. The patient was likely in an alcoholic stupor when the fire broke out and could not escape.</spoiler>

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 === Images ===
-* [http://peir.path.uab.edu/library/index.php?/tags/2171-burn PEIR Digital Library: Burn Images]
+* [{{SERVER}}/library/index.php?/tags/2171-burn PEIR Digital Library: Burn Images]
 {{IPLab 12}}
 [[Category: IPLab:Lab 12]]

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 == Additional Resources ==
 === Reference ===
+* [http://emedicine.medscape.com/article/1278244-overview eMedicine Medical Library: Thermal Burns]
 === Journal Articles ===