IPLab:Lab 10:Histoplasmosis - Revision history

Peter Anderson: /* Images */

2020-07-09T21:53:17Z

Images

← Older revision		Revision as of 16:53, 9 July 2020
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	== Images ==		== Images ==
	<gallery heights="250px" widths="250px">		<gallery heights="250px" widths="250px">
	File:~~IPLab10Histo1~~.jpg\|This low-power photomicrograph shows a section of adrenal gland with several irregularly-outlined areas of necrosis.		File:IPLab10Histo1b.jpg\|This low-power photomicrograph shows a section of adrenal gland with several irregularly-outlined areas of necrosis.
	File:IPLab10Histo2.jpg\|This higher-power photomicrograph of the previous adrenal gland shows more clearly the irregularly-shaped area of necrosis (arrows).		File:IPLab10Histo2.jpg\|This higher-power photomicrograph of the previous adrenal gland shows more clearly the irregularly-shaped area of necrosis (arrows).
	File:IPLab10Histo3.jpg\|This is an even higher-power photomicrograph of an area of necrosis (arrows). There is loss of cellular detail within this area. There are inflammatory cells present; however, it is difficult to differentiate the inflammatory cells from the native lymphocytes of the adrenal gland--which is a lymph node.		File:IPLab10Histo3.jpg\|This is an even higher-power photomicrograph of an area of necrosis (arrows). There is loss of cellular detail within this area. There are inflammatory cells present; however, it is difficult to differentiate the inflammatory cells from the native lymphocytes of the adrenal gland--which is a lymph node.

2020-07-09T21:46:16Z

Clinical Summary

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	== Clinical Summary ==		== Clinical Summary ==

	For four months before death, this two-year-old black female infant ate poorly and lost weight. When hospitalized, she appeared chronically ill with signs of infection. An exploratory laparotomy showed the patient had enormously enlarged abdominal lymph nodes, the biopsy of which disclosed active histoplasmosis. Despite intensive therapy, the patient died three weeks after admission.		For four months before death, this two-year-old black female infant ate poorly and lost weight. When hospitalized, she appeared chronically ill with signs of infection. An exploratory laparotomy showed the patient had enormously enlarged abdominal lymph nodes, the biopsy of which disclosed active histoplasmosis. Despite intensive therapy, the patient died three weeks after admission.

			Autopsy showed widespread enlargement of lymph nodes, ulcers of the intestines, and enlarged adrenal glands exhibiting multifocal granulomas.

	== Images ==		== Images ==

2020-07-09T21:46:03Z

Autopsy Findings

← Older revision		Revision as of 16:46, 9 July 2020
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	For four months before death, this two-year-old black female infant ate poorly and lost weight. When hospitalized, she appeared chronically ill with signs of infection. An exploratory laparotomy showed the patient had enormously enlarged abdominal lymph nodes, the biopsy of which disclosed active histoplasmosis. Despite intensive therapy, the patient died three weeks after admission.		For four months before death, this two-year-old black female infant ate poorly and lost weight. When hospitalized, she appeared chronically ill with signs of infection. An exploratory laparotomy showed the patient had enormously enlarged abdominal lymph nodes, the biopsy of which disclosed active histoplasmosis. Despite intensive therapy, the patient died three weeks after admission.

	~~== Autopsy Findings ==~~

	~~Autopsy showed widespread enlargement of lymph nodes, ulcers of the intestines, and enlarged adrenal glands exhibiting multifocal granulomas.~~

	== Images ==		== Images ==

2014-01-03T16:34:00Z

← Older revision		Revision as of 11:34, 3 January 2014
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	File:IPLab10Histo7.jpg\|This photomicrograph was taken under oil immersion to show the silver-stained Histoplasma organisms. Some of the organisms appear to be budding (arrows).		File:IPLab10Histo7.jpg\|This photomicrograph was taken under oil immersion to show the silver-stained Histoplasma organisms. Some of the organisms appear to be budding (arrows).
	</gallery>		</gallery>

			== Virtual Microscopy ==
			=== H&E ===
			<peir-vm>IPLab10Histo_HE</peir-vm>

			=== GMS ===
			<peir-vm>IPLab10Histo_GMS</peir-vm>

	== Study Questions ==		== Study Questions ==

2013-08-30T01:45:00Z

Images

← Older revision		Revision as of 20:45, 29 August 2013
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	=== Images ===		=== Images ===
	* [~~http://peir.path.uab.edu~~/library/index.php?/tags/263-histoplasmosis PEIR Digital Library: Histoplasmosis]		* [{{SERVER}}/library/index.php?/tags/263-histoplasmosis PEIR Digital Library: Histoplasmosis]
	* [http://library.med.utah.edu/WebPath/INFEHTML/INFECIDX.html WebPath: Infection]		* [http://library.med.utah.edu/WebPath/INFEHTML/INFECIDX.html WebPath: Infection]

2013-08-24T03:21:23Z

Images

← Older revision		Revision as of 22:21, 23 August 2013
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	=== Images ===		=== Images ===
			* [http://peir.path.uab.edu/library/index.php?/tags/263-histoplasmosis PEIR Digital Library: Histoplasmosis]
			* [http://library.med.utah.edu/WebPath/INFEHTML/INFECIDX.html WebPath: Infection]

	{{IPLab 10}}		{{IPLab 10}}

	[[Category: IPLab:Lab 10]]		[[Category: IPLab:Lab 10]]

2013-08-24T03:20:31Z

Related IPLab Cases

2013-08-24T03:20:21Z

Journal Articles

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	=== Journal Articles ===		=== Journal Articles ===
			* de Pauw BE. [http://www.ncbi.nlm.nih.gov/pubmed/11429012 Advances in the management of invasive fungal infections in organ transplant recipients: step by step]. ''Transpl Infect Dis'' 2000 Jun;2(2):48-50.

	=== Images ===		=== Images ===

2013-08-24T03:19:42Z

Reference

← Older revision		Revision as of 22:19, 23 August 2013
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	== Additional Resources ==		== Additional Resources ==
	=== Reference ===		=== Reference ===
			* [http://emedicine.medscape.com/article/299054-overview eMedicine Medical Library: Histoplasmosis]
			* [http://www.merckmanuals.com/professional/infectious_diseases/fungi/histoplasmosis.html Merck Manual: Histoplasmosis]

	=== Journal Articles ===		=== Journal Articles ===

2013-08-23T04:24:25Z

← Older revision		Revision as of 23:24, 22 August 2013
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	Histoplasma yeasts are phagocytosed by the unstimulated macrophages, multiply within the phagolysosome, and lyse the host cells.</spoiler>		Histoplasma yeasts are phagocytosed by the unstimulated macrophages, multiply within the phagolysosome, and lyse the host cells.</spoiler>

			== Additional Resources ==
			=== Reference ===


			=== Journal Articles ===


			=== Images ===


			== Related IPLab Cases ==


	{{IPLab 10}}		{{IPLab 10}}

	[[Category: IPLab:Lab 10]]		[[Category: IPLab:Lab 10]]