IPLab:Lab 10:Blastomycosis - Revision history

Peter Anderson: /* Clinical Summary */

2020-07-09T21:57:27Z

Clinical Summary

← Older revision		Revision as of 16:57, 9 July 2020
Line 2:		Line 2:
	About three weeks before his death, this 17-year-old white male developed a "chest cold" which gradually worsened. The patient was eventually admitted three days before his death. At that time, the patient was very dyspneic. Chest x-ray showed consolidation of the entire left lung. The initial impression by his care team was staphylococcal pneumonia. However, Blastomyces dermatitides was identified in stained smears of sputum the next day. In spite of appropriate antifungal therapy, the patient deteriorated rapidly and died.		About three weeks before his death, this 17-year-old white male developed a "chest cold" which gradually worsened. The patient was eventually admitted three days before his death. At that time, the patient was very dyspneic. Chest x-ray showed consolidation of the entire left lung. The initial impression by his care team was staphylococcal pneumonia. However, Blastomyces dermatitides was identified in stained smears of sputum the next day. In spite of appropriate antifungal therapy, the patient deteriorated rapidly and died.

	At autopsy the both lungs had areas of consolidation and ~~had multiple hemorrhagic areas~~.		At autopsy the both lungs had areas of consolidation and necrosis.

	== Images ==		== Images ==

Peter Anderson: /* Clinical Summary */

2020-07-09T21:56:38Z

Clinical Summary

← Older revision		Revision as of 16:56, 9 July 2020
Line 2:		Line 2:
	About three weeks before his death, this 17-year-old white male developed a "chest cold" which gradually worsened. The patient was eventually admitted three days before his death. At that time, the patient was very dyspneic. Chest x-ray showed consolidation of the entire left lung. The initial impression by his care team was staphylococcal pneumonia. However, Blastomyces dermatitides was identified in stained smears of sputum the next day. In spite of appropriate antifungal therapy, the patient deteriorated rapidly and died.		About three weeks before his death, this 17-year-old white male developed a "chest cold" which gradually worsened. The patient was eventually admitted three days before his death. At that time, the patient was very dyspneic. Chest x-ray showed consolidation of the entire left lung. The initial impression by his care team was staphylococcal pneumonia. However, Blastomyces dermatitides was identified in stained smears of sputum the next day. In spite of appropriate antifungal therapy, the patient deteriorated rapidly and died.

	At autopsy the ~~entire left lung was consolidated~~ and had multiple hemorrhagic areas.		At autopsy the both lungs had areas of consolidation and had multiple hemorrhagic areas.

	== Images ==		== Images ==

Peter Anderson: /* Clinical Summary */

2020-07-09T21:55:45Z

Clinical Summary

← Older revision		Revision as of 16:55, 9 July 2020
Line 1:		Line 1:
	== Clinical Summary ==		== Clinical Summary ==
			About three weeks before his death, this 17-year-old white male developed a "chest cold" which gradually worsened. The patient was eventually admitted three days before his death. At that time, the patient was very dyspneic. Chest x-ray showed consolidation of the entire left lung. The initial impression by his care team was staphylococcal pneumonia. However, Blastomyces dermatitides was identified in stained smears of sputum the next day. In spite of appropriate antifungal therapy, the patient deteriorated rapidly and died.

	~~About three weeks before his death, this 17-year-old white male developed a "chest cold" which gradually worsened. The patient was eventually admitted three days before his death.~~ At ~~that time, the patient was very dyspneic. Chest x-ray showed consolidation of~~ the entire left lung~~. The initial impression by his care team was staphylococcal pneumonia. However, Blastomyces dermatitides~~ was ~~identified in stained smears of sputum the next day. In spite of appropriate antifungal therapy, the patient deteriorated rapidly~~ and ~~died~~.		At autopsy the entire left lung was consolidated and had multiple hemorrhagic areas.

	== Images ==		== Images ==

Peter Anderson: /* Autopsy Findings */

2020-07-09T21:54:26Z

Autopsy Findings

← Older revision		Revision as of 16:54, 9 July 2020
Line 2:		Line 2:

	About three weeks before his death, this 17-year-old white male developed a "chest cold" which gradually worsened. The patient was eventually admitted three days before his death. At that time, the patient was very dyspneic. Chest x-ray showed consolidation of the entire left lung. The initial impression by his care team was staphylococcal pneumonia. However, Blastomyces dermatitides was identified in stained smears of sputum the next day. In spite of appropriate antifungal therapy, the patient deteriorated rapidly and died.		About three weeks before his death, this 17-year-old white male developed a "chest cold" which gradually worsened. The patient was eventually admitted three days before his death. At that time, the patient was very dyspneic. Chest x-ray showed consolidation of the entire left lung. The initial impression by his care team was staphylococcal pneumonia. However, Blastomyces dermatitides was identified in stained smears of sputum the next day. In spite of appropriate antifungal therapy, the patient deteriorated rapidly and died.

	~~== Autopsy Findings ==~~

	~~Autopsy confirmed that the entire left lung was semi-solid.~~

	== Images ==		== Images ==

Seung Park at 16:35, 3 January 2014

2014-01-03T16:35:18Z

← Older revision		Revision as of 11:35, 3 January 2014
Line 20:		Line 20:
	File:IPLab10Blasto10.jpg\|This is a very high-power photomicrograph showing Blastomyces organisms stained with PAS. Note the budding organism (arrow) and the underlying pyogranulomatous inflammatory reaction in the background.		File:IPLab10Blasto10.jpg\|This is a very high-power photomicrograph showing Blastomyces organisms stained with PAS. Note the budding organism (arrow) and the underlying pyogranulomatous inflammatory reaction in the background.
	</gallery>		</gallery>

			== Virtual Microscopy ==
			=== H&E ===
			<peir-vm>IPLab10Blasto_HE</peir-vm>

			=== PAS ===
			<peir-vm>IPLab10Blasto_PAS</peir-vm>

	== Study Questions ==		== Study Questions ==

Seung Park: /* Images */

2013-08-30T01:45:32Z

Images

← Older revision		Revision as of 20:45, 29 August 2013
Line 37:		Line 37:

	=== Images ===		=== Images ===
	* [~~http://peir.path.uab.edu~~/library/index.php?/tags/542-blastomycosis PEIR Digital Library: Blastomycosis Images]		* [{{SERVER}}/library/index.php?/tags/542-blastomycosis PEIR Digital Library: Blastomycosis Images]
	* [http://library.med.utah.edu/WebPath/INFEHTML/INFECIDX.html Webpath: Infection]		* [http://library.med.utah.edu/WebPath/INFEHTML/INFECIDX.html Webpath: Infection]

Seung Park: /* Related IPLab Cases */

2013-08-24T03:30:25Z

Related IPLab Cases

← Older revision		Revision as of 22:30, 23 August 2013
Line 39:		Line 39:
	* [http://peir.path.uab.edu/library/index.php?/tags/542-blastomycosis PEIR Digital Library: Blastomycosis Images]		* [http://peir.path.uab.edu/library/index.php?/tags/542-blastomycosis PEIR Digital Library: Blastomycosis Images]
	* [http://library.med.utah.edu/WebPath/INFEHTML/INFECIDX.html Webpath: Infection]		* [http://library.med.utah.edu/WebPath/INFEHTML/INFECIDX.html Webpath: Infection]

	~~== Related IPLab Cases ==~~
	* [[IPLab:Lab 5:α1 Antitrypsin Deficiency\|Lab 5: Lung: α1-Antitrypsin Deficiency]]
	* [[IPLab:Lab 12:COPD\|Lab 12: Lung: Chronic Obstructive Pulmonary Disease]]

	{{IPLab 10}}		{{IPLab 10}}

	[[Category: IPLab:Lab 10]]		[[Category: IPLab:Lab 10]]

Seung Park: /* Images */

2013-08-24T03:30:09Z

Images

← Older revision		Revision as of 22:30, 23 August 2013
Line 37:		Line 37:

	=== Images ===		=== Images ===
			* [http://peir.path.uab.edu/library/index.php?/tags/542-blastomycosis PEIR Digital Library: Blastomycosis Images]
			* [http://library.med.utah.edu/WebPath/INFEHTML/INFECIDX.html Webpath: Infection]

	== Related IPLab Cases ==		== Related IPLab Cases ==

Seung Park: /* Journal Articles */

2013-08-24T03:27:52Z

Journal Articles

← Older revision		Revision as of 22:27, 23 August 2013
Line 34:		Line 34:

	=== Journal Articles ===		=== Journal Articles ===
			* Rooney PJ, Klein BS. [http://www.ncbi.nlm.nih.gov/pubmed/11906450 Linking fungal morphogenesis with virulence]. ''Cell Microbiol'' 2002 Mar;4(3):127-37.

	=== Images ===		=== Images ===

Seung Park: /* Reference */

2013-08-24T03:27:13Z

Reference

← Older revision		Revision as of 22:27, 23 August 2013
Line 29:		Line 29:
	== Additional Resources ==		== Additional Resources ==
	=== Reference ===		=== Reference ===
			* [http://emedicine.medscape.com/article/354067-overview eMedicine Medical Library: Imaging in Thoracic Blastomycosis]
			* [http://emedicine.medscape.com/article/296870-overview eMedicine Medical Library: Blastomycosis]
			* [http://www.merckmanuals.com/professional/infectious_diseases/fungi/blastomycosis.html Merck Manual: Blastomycosis]

	=== Journal Articles ===		=== Journal Articles ===