Histologic:Chapter 8 - Revision history

Seung Park at 23:54, 28 July 2014

2014-07-28T23:54:43Z

Matthew Anderson: /* Spleen */

2014-07-11T22:46:33Z

‎Spleen

Matthew Anderson: /* Thymus */

2014-07-11T22:44:19Z

‎Thymus

Matthew Anderson: /* Lymph Nodes */

2014-07-11T22:42:02Z

‎Lymph Nodes

Matthew Anderson at 22:32, 11 July 2014

2014-07-11T22:32:18Z

Show changes

Matthew Anderson: /* Slide 63, Lymph Node, and slide 35, Mesenteric Lymph Nodes (H&E) */

2014-07-11T22:13:55Z

‎Slide 63, Lymph Node, and slide 35, Mesenteric Lymph Nodes (H&E)

Matthew Anderson: /* Slide 63, Lymph Node, and slide 35, Mesenteric Lymph Nodes (H&E) */

2014-07-11T22:13:06Z

‎Slide 63, Lymph Node, and slide 35, Mesenteric Lymph Nodes (H&E)

Matthew Anderson at 22:12, 11 July 2014

2014-07-11T22:12:29Z

Show changes

Matthew Anderson: Created page with "== Introduction =="

2014-07-11T21:50:31Z

Created page with "== Introduction =="

New page

== Introduction ==

@@ Line 7: / Line 7: @@
 Lymph nodes are round, ovoid or bean-shaped organs found widely distributed in the body. Important groups of lymph nodes occur in chains along the course of blood vessels in such regions as the axilla, groin and mesentery.  Lymph nodes are the only lymphatic organs to have an afferent lymphatic supply. They are interposed in the lymphatic drainage of numerous regions of the body. The lymph flowing through the nodes is filtered and phagocytic activity occurs on the particulate matter carried in the lymph. Lymph nodes are important centers for the production of lymphocytes, plasma cells and antibodies. Lymphocytes and antibodies are added to the lymph, which leaves the node by way of the efferent lymph vessels. Lymph nodes are fixed to surrounding connective tissue by loosely arranged fibers that continue into the capsule of the node.
-=== Slide 63, Lymph Node, and slide 35, Mesenteric Lymph Nodes (H&E) ===
+=== Slide 63: Lymph Node, and Slide 35: Mesenteric Lymph Nodes (H&E) ===
 Scan these sections with low power to observe the large number of small darkly staining cells. Most of these cells are lymphocytes. On slide 35, study the largest node first.
@@ Line 37: / Line 37: @@
 *Efferent lymph vessels collect the lymph from the medullary sinuses.
-==== Slide 63, Lymph Node ====
+==== Slide 63: Lymph Node ====
 <peir-vm>UAB-Histology-00063</peir-vm>
-==== Slide 35, Mesenteric Lymph Nodes (H&E) ====
+==== Slide 35: Mesenteric Lymph Nodes (H&E) ====
 <peir-vm>UAB-Histology-00035</peir-vm>
-=== Slide 93, Lymph node (H&E) ===
+=== Slide 93: Lymph node (H&E) ===
 Slide 93, Lymph node (H&E) in the hilus of the lung. These nodes help filter dust, carbon particles, and other debris that get into the lungs.
@@ Line 55: / Line 55: @@
 <peir-vm>UAB-Histology-00093</peir-vm>
-====  Slide 35, Mesenteric Lymph Nodes (H&E) ====
+====  Slide 35: Mesenteric Lymph Nodes (H&E) ====
 In slide 35 note that most of the lymphatic nodules contain germinal centers containing small and medium-sized lymphocytes, macrophages, and lymphoblasts (few in number).
@@ Line 63: / Line 63: @@
 <peir-vm>UAB-Histology-00035</peir-vm>
-==== Slide 63, Lymph Node ====
+==== Slide 63: Lymph Node ====
 Lymphoblasts (large lymphocytes) are more easily recognized on slide 63, although fewer germinal centers are present on this slide. To identify lymphoblasts, look in the germinal centers for relatively large cells that have basophilic cytoplasm (not very distinct on our slides) and a large mostly euchromatic nucleus with one or two prominent nucleoli.
@@ Line 79: / Line 79: @@
 Four slides of thymic tissue are to be studied.  Slides 55 and 61 are from young individuals.  Slide 60 is from a nineteen-year-old, and slide 59 is an involuted thymus from a fifty-year-old person.  Since the thymus responds to illness by undergoing stress involution, it should be realized that some sections might not be optimal for studying all features. Slide 55 from a ten-day old child best shows the normal features for a young thymus.
-=== Slide 55, Thymus (Infant)(H&E) ===
+=== Slide 55: Thymus (Infant) (H&E) ===
 Observe the thin connective tissue capsule surrounding this organ and the septa (trabeculae) which project inward from the capsule. These strands of connective tissue subdivide the thymus into lobules.  Blood vessels are contained within some of the larger septa.
@@ Line 96: / Line 96: @@
 <peir-vm>UAB-Histology-00055</peir-vm>
-=== Slide 61, Thymus (H&E) ===
+=== Slide 61: Thymus (H&E) ===
 Slide 61, Thymus, (H&E) is from a seven-year-old child.  Identify as many features as possible. Observe how different this thymus appears from the section of the younger thymus previously studied on Slide 55. Slightly more connective tissue and fat are present in the seven-year-old thymus and the thymic corpuscles are larger.
@@ Line 102: / Line 102: @@
 <peir-vm>UAB-Histology-00061</peir-vm>
-=== Slide 60, Thymus (H&E) ===
+=== Slide 60: Thymus (H&E) ===
 Study slide 60, Thymus (H&E) from a nineteen-year-old. Note the reduced number of lobules that are widely separated by a large increase in the amount of fat. Identify the thymic corpuscles. Observe that arterioles, venules, and larger blood vessels are absent from the cortex of the lobules.  The thick-walled capillaries that form the blood-thymus barrier are not readily identifiable on our slides.
@@ Line 108: / Line 108: @@
 <peir-vm>UAB-Histology-00060</peir-vm>
-=== Slide 59, Thymus (H&E) ===
+=== Slide 59: Thymus (H&E) ===
 Study slide 59, Thymus (H&E) from a fifty-year-old individual. Compare this involuted thymus with the sections of thymus previously studied.
@@ Line 120: / Line 120: @@
 === Palatine Tonsil ===
-==== Slide 52, Palatine Tonsil (H&E) ====
+==== Slide 52: Palatine Tonsil (H&E) ====
 Observe that “one side,” the surface, is covered by stratified squamous epithelium. From the surface a total of 10 to 20 deeply invaginated epithelial pockets called crypts extend into the substance of the organ. Note that the epithelium lining the crypts is continuous with the surface epithelium. Only a few crypts will be present on any one slide.
@@ Line 146: / Line 146: @@
 The nodules originate in the lamina propria but they may extend into the submucosa disrupting the muscularis mucosae. Where the nodules project to the luminal surface of the ileum, villi are absent.
-==== Slide 31, Ileum (H&E) ====
+==== Slide 31: Ileum (H&E) ====
 <peir-vm>UAB-Histology-00031</peir-vm>
-==== Slide 168, Ileum (H&E) ====
+==== Slide 168: Ileum (H&E) ====
 <peir-vm>UAB-Histology-00168</peir-vm>
-==== Slide 172, Ileum (H&E) ====
+==== Slide 172: Ileum (H&E) ====
 <peir-vm>UAB-Histology-00172</peir-vm>
@@ Line 159: / Line 159: @@
 The spleen is an organ which both forms and destroys blood cells. In the embryo the spleen is a fully hemopoietic organ generating all the kinds of blood cells. In late fetal life the spleen stops producing erythrocytes and granulocytes, but it continues to generate lymphocytes and monocytes. However, it retains full hemopoietic potentialities so that pathologically, in adulthood, the spleen may once again initiate the functions of red bone marrow. The spleen is highly active in the production of antibodies. Plasma cells are the main source of the antibodies.  The spleen also serves as a specialized blood-filtering organ and it can serve for the temporary storage of platelets and erythrocytes.
-=== Slide 18, Spleen (H&E) ===
+=== Slide 18: Spleen (H&E) ===
 Examine slide 18, Spleen (H&E) and identify the capsule and trabeculae
@@ Line 177: / Line 177: @@
 <peir-vm>UAB-Histology-00018</peir-vm>
-==== Slide 19, Spleen (PASH) ====
+==== Slide 19: Spleen (PASH) ====
 The pulp cords consist of the tissue occupying the narrow areas between the venous sinuses.  With high power, study the splenic sinuses and pulp cords. Note how much easier it is to identify the venous sinuses by using the PASH stained section of Spleen (slide 19, Spleen PASH).

@@ Line 156: / Line 156: @@
 == Spleen ==
+[[File:HistologicChapter8Spleen.jpg|thumb|200px|Spleen]]
 The spleen is an organ which both forms and destroys blood cells. In the embryo the spleen is a fully hemopoietic organ generating all the kinds of blood cells. In late fetal life the spleen stops producing erythrocytes and granulocytes, but it continues to generate lymphocytes and monocytes. However, it retains full hemopoietic potentialities so that pathologically, in adulthood, the spleen may once again initiate the functions of red bone marrow. The spleen is highly active in the production of antibodies. Plasma cells are the main source of the antibodies.  The spleen also serves as a specialized blood-filtering organ and it can serve for the temporary storage of platelets and erythrocytes.

@@ Line 74: / Line 74: @@
 == Thymus ==
+[[File:HistologicChapter8Thymus.jpg|thumb|200px|Thymus]]
 The thymus is unlike other lymphatic organs in two major respects: (1) its stroma consists of a framework of connecting epithelial reticular cells (cytoreticular cells) derived from endoderm. This stroma is not typical reticular connective tissue that is derived from mesoderm and characteristic of other lymphatic organs. (2) Lymphatic nodules are lacking, but the organization of the lobules into a cortex and a medulla may give the unwary student the impression that nodules are present.
@@ Line 113: / Line 113: @@
 <peir-vm>UAB-Histology-00059</peir-vm>
-−
 == Tonsils ==

@@ Line 4: / Line 4: @@
 == Lymph Nodes ==
+[[File:HistologicChapter8LymphNode.png|thumb|200px|Lymph Node]]
 Lymph nodes are round, ovoid or bean-shaped organs found widely distributed in the body. Important groups of lymph nodes occur in chains along the course of blood vessels in such regions as the axilla, groin and mesentery.  Lymph nodes are the only lymphatic organs to have an afferent lymphatic supply. They are interposed in the lymphatic drainage of numerous regions of the body. The lymph flowing through the nodes is filtered and phagocytic activity occurs on the particulate matter carried in the lymph. Lymph nodes are important centers for the production of lymphocytes, plasma cells and antibodies. Lymphocytes and antibodies are added to the lymph, which leaves the node by way of the efferent lymph vessels. Lymph nodes are fixed to surrounding connective tissue by loosely arranged fibers that continue into the capsule of the node.

@@ Line 37: / Line 37: @@
 *Efferent lymph vessels collect the lymph from the medullary sinuses.
-Slide 63, Lymph Node
+==== Slide 63, Lymph Node ====
 <peir-vm>UAB-Histology-00063</peir-vm>
-Slide 35, Mesenteric Lymph Nodes (H&E)
+==== Slide 35, Mesenteric Lymph Nodes (H&E) ====
 <peir-vm>UAB-Histology-00035</peir-vm>