Cytologically Yours: CoW: 20140106 - Revision history

Jessica Levesque: /* Cell Block */

2014-06-26T21:33:17Z

‎Cell Block

Jessica Levesque: /* Cytology */

2014-06-26T21:33:04Z

‎Cytology

Jessica Levesque: Created page with "== Clinical Summary == 64 year old male who presented to the ED with shortness of breath. === Past Medical History === * Hypertension * Dyslipidemia * Recent diagnosis of ..."

2014-06-26T21:22:50Z

Created page with "== Clinical Summary == 64 year old male who presented to the ED with shortness of breath. === Past Medical History === * Hypertension * Dyslipidemia * Recent diagnosis of ..."

New page

== Clinical Summary ==
64 year old male who presented to the ED with shortness of breath.

=== Past Medical History ===
* Hypertension
* Dyslipidemia
* Recent diagnosis of metastatic melanoma of unknown primary

=== Past Surgical History ===
* Metastatic melanoma of unknown primary diagnosed in an enlarged axillary mass that was removed several months previously.

==Radiology==
* CXR and CT showed multiple pulmonary nodules and bilateral pleural effusions.

===Clinical Plan===
Thoracentesis

==Pathology==

===Cytology===
<gallery heights="250px" widths="250px">
CytologicallyYoursCoW20140106Cytology1.JPG|10x magnification of a very cellular specimen. (DQ)
CytologicallyYoursCoW20140106Cytology2.JPG|40x magnification showing cells that have ample cytoplasm and prominent nucleoli.(DQ)
CytologicallyYoursCoW20140106Cytology3.JPG|40x magnification showing Cells with abundant cytoplasm some with granular material in the cytoplasm. These cells also have prominent nucleoli.(DQ)
CytologicallyYoursCoW20140106Cytology4.JPG|10x magnification of a very cellular specimen. (Pap)
CytologicallyYoursCoW20140106Cytology5.JPG|40x magnification of cells with prominent nucleoli and dusty cytoplasm. (Pap)

</gallery>

<div class="usermessage mw-customtoggle-diagnosis" style="cursor:pointer">Click here to toggle the diagnosis and discussion.</div>
<div class="mw-collapsible mw-collapsed" id="mw-customcollapsible-diagnosis">
<div class="mw-collapsible-content">

==Final Diagnosis==
===Cytology===
* '''Metastatic melanoma'''.

===Cell Block===
<gallery heights="250px" widths="250px">
CytologicallyYoursCoW20140106Cytology6.JPG|40x magnification of cell block showing cells with pigment in the cytoplasm.
CytologicallyYoursCoW20140106Cytology7.JPG|20x magnification of MITF staining of the cell block.
</gallery>

===Discussion===
Melanoma is "the great mimicer", it's cytomorphology can be very variable. Prominent nucleoli and pigment are some of the features that can help guide a pathologist to the diagnosis.
The use of the immunohistochemical markers MART-1, S100, MITF,and MelanA are useful for the diagnosis of melanoma.

</div></div>

{{Cytologically Yours}}

[[Category:Case Reports]]

@@ Line 39: / Line 39: @@
 ===Cell Block===
 <gallery heights="250px" widths="250px">
-CytologicallyYoursCoW20140106Cytology6.JPG|40x magnification of cell block showing cells with pigment in the cytoplasm.
+CytologicallyYoursCoW20140106Cytology6.jpg|40x magnification of cell block showing cells with pigment in the cytoplasm.
-CytologicallyYoursCoW20140106Cytology7.JPG|20x magnification of MITF staining of the cell block.
+CytologicallyYoursCoW20140106Cytology7.jpg|20x magnification of MITF staining of the cell block.
 </gallery>

@@ Line 20: / Line 20: @@
 ===Cytology===
 <gallery heights="250px" widths="250px">
-CytologicallyYoursCoW20140106Cytology1.JPG|10x magnification of a very cellular specimen. (DQ)
+CytologicallyYoursCoW20140106Cytology1.jpg|10x magnification of a very cellular specimen. (DQ)
-CytologicallyYoursCoW20140106Cytology2.JPG|40x magnification showing cells that have ample cytoplasm and prominent nucleoli.(DQ)
+CytologicallyYoursCoW20140106Cytology2.jpg|40x magnification showing cells that have ample cytoplasm and prominent nucleoli.(DQ)
-CytologicallyYoursCoW20140106Cytology3.JPG|40x magnification showing Cells with abundant cytoplasm some with granular material in the cytoplasm. These cells also have prominent nucleoli.(DQ)
+CytologicallyYoursCoW20140106Cytology3.jpg|40x magnification showing Cells with abundant cytoplasm some with granular material in the cytoplasm. These cells also have prominent nucleoli.
-CytologicallyYoursCoW20140106Cytology4.JPG|10x magnification of a very cellular specimen. (Pap)
+CytologicallyYoursCoW20140106Cytology4.jpg|10x magnification of a very cellular specimen. (Pap)
-CytologicallyYoursCoW20140106Cytology5.JPG|40x magnification of cells with prominent nucleoli and dusty cytoplasm. (Pap)
+CytologicallyYoursCoW20140106Cytology5.jpg|40x magnification of cells with prominent nucleoli and dusty cytoplasm. (Pap)
 </gallery>