CRP-35 - Revision history

Peter Anderson at 14:33, 8 October 2026

2026-10-08T14:33:59Z

← Older revision		Revision as of 09:33, 8 October 2026
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	<div class="usermessage mw-customtoggle-diagnosis" style="cursor:pointer"> Microscopic Description, Immunofluorescence, and Electron Microscopy.</div>		<div class="usermessage mw-customtoggle-diagnosis" style="cursor:pointer"> Microscopic Description, Immunofluorescence, and Electron Microscopy</div>
	<div class="mw-collapsible mw-collapsed" id="mw-customcollapsible-diagnosis">		<div class="mw-collapsible mw-collapsed" id="mw-customcollapsible-diagnosis">
	<div class="mw-collapsible-content">		<div class="mw-collapsible-content">

Peter Anderson at 13:10, 8 October 2026

2026-10-08T13:10:57Z

← Older revision		Revision as of 08:10, 8 October 2026
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	'''CRP-35'''		'''CRP-35'''
	==Clinical History==		==Clinical History==
			The patient is a 25 year old female who is status post renal transplant two years ago. She presents for explant nephrectomy due to rejection.

	==Gross Description:==		==Gross Description==
			The specimen is received in a container labeled with the patient's name, medical record number and “transplant nephrectomy”. Received in saline solution is a fragmented and distorted nephrectomy specimen that weighs in aggregate 250 grams and measures 15 x 8 x 4 cm in greatest dimension. The kidney is externally covered by a tan-pink shiny capsule with areas of petechial hemorrhages. This capsule strips with ease, revealing a red-brown granular external surface. The cut surface is pale tan with congestion. The cortico-medullary junction cannot be grossly identified and the portion of pelvico-calyceal system that can be grossly identified, is lined by a tan-white smooth glistening and congested mucosa. No gross lesions are present. The specimen is submitted in four cassettes.

	==Pathology==		==Pathology==
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	<div class="mw-collapsible-content">		<div class="mw-collapsible-content">

	==Microscopic Description:==		==Microscopic Description==
	===Light Microscopy:===		===Light Microscopy===
			A1-A4 – Sections through transplant kidney. A microscopic examination has been performed.
	~~===Immunofluorescence:===~~


	~~===Electron Microscopy:===~~

			===Immunofluorescence===
			IHC-CD68

	</div></div>		</div></div>

	<spoiler text="Diagnosis and Comments">		<spoiler text="Diagnosis and Comments">
			Kidney, transplant nephrectomy – Malakoplakia
			- Moderately severe chronic vascular rejection and acute vascular rejection
			- Acute tubulitis.
			- Tubular atrophy and interstitial fibrosis

			Much of the renal parenchyma is replaced by sheets of large eosinophilic macrophages with occasional small round structures in their cytoplasm, consistent with Michaelis-Guttman bodies. These macrophages stain strongly with CD68 and are negative for cytokeratin. The stains for fungal organisms, acid fast bacilli and Whipples bacteria are negative.

	</spoiler>		</spoiler>

Peter Anderson: Created page with "'''CRP-35''' ==Clinical History== ==Gross Description:== ==Pathology== ===Case CRP-035 H&E=== specialcrp/CRP-035_HE ===Case CRP-035 PASH=== specialcrp/CRP-035_PASH ===Case CRP-035 IHC=== specialcrp/CRP-035_IHC ===Case CRP-035 IHC_control=== specialcrp/CRP-035_IHC_control
Microscopic Description, Immunofluorescence, and..."

2026-10-07T18:05:59Z

Created page with "'''CRP-35''' ==Clinical History== ==Gross Description:== ==Pathology== ===Case CRP-035 H&E=== <peir-vm>specialcrp/CRP-035_HE</peir-vm> ===Case CRP-035 PASH=== <peir-vm>specialcrp/CRP-035_PASH</peir-vm> ===Case CRP-035 IHC=== <peir-vm>specialcrp/CRP-035_IHC</peir-vm> ===Case CRP-035 IHC_control=== <peir-vm>specialcrp/CRP-035_IHC_control</peir-vm> <div class="usermessage mw-customtoggle-diagnosis" style="cursor:pointer"> Microscopic Description, Immunofluorescence, and..."

New page

'''CRP-35'''
==Clinical History==

==Gross Description:==

==Pathology==
===Case CRP-035 H&E===
<peir-vm>specialcrp/CRP-035_HE</peir-vm>
===Case CRP-035 PASH===
<peir-vm>specialcrp/CRP-035_PASH</peir-vm>
===Case CRP-035 IHC===
<peir-vm>specialcrp/CRP-035_IHC</peir-vm>
===Case CRP-035 IHC_control===
<peir-vm>specialcrp/CRP-035_IHC_control</peir-vm>

<div class="usermessage mw-customtoggle-diagnosis" style="cursor:pointer"> Microscopic Description, Immunofluorescence, and Electron Microscopy.</div>
<div class="mw-collapsible mw-collapsed" id="mw-customcollapsible-diagnosis">
<div class="mw-collapsible-content">

==Microscopic Description:==
===Light Microscopy:===

===Immunofluorescence:===

===Electron Microscopy:===

</div></div>

<spoiler text="Diagnosis and Comments">

</spoiler>