CRP-31 - Revision history

Peter Anderson at 14:32, 8 October 2026

2026-10-08T14:32:40Z

← Older revision		Revision as of 09:32, 8 October 2026
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	<div class="usermessage mw-customtoggle-diagnosis" style="cursor:pointer"> Microscopic Description, Immunofluorescence, and Electron Microscopy.</div>		<div class="usermessage mw-customtoggle-diagnosis" style="cursor:pointer"> Microscopic Description, Immunofluorescence, and Electron Microscopy</div>
	<div class="mw-collapsible mw-collapsed" id="mw-customcollapsible-diagnosis">		<div class="mw-collapsible mw-collapsed" id="mw-customcollapsible-diagnosis">
	<div class="mw-collapsible-content">		<div class="mw-collapsible-content">

Peter Anderson at 12:58, 8 October 2026

2026-10-08T12:58:34Z

← Older revision		Revision as of 07:58, 8 October 2026
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	'''CRP-31'''		'''CRP-31'''
	==Clinical History==		==Clinical History==
			The patient is a 36 year old black male with chronic rejection.

	==Gross Description:==		==Gross Description==
			Received in saline is one wedge shaped fragment of cortex measuring 5 x 3 x 2 mm in greatest dimensions. This is bisected, and one-half is submitted for light microscopy. Note that the surgical pathology request sheet states that this is a transplant nephrectomy, but the only specimen received is this wedge shaped fragment.==Pathology==
	==Pathology==
	===Case CRP-031 H&E===		===Case CRP-031 H&E===
	<peir-vm>specialcrp/CRP-031_HE</peir-vm>		<peir-vm>specialcrp/CRP-031_HE</peir-vm>
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	<div class="mw-collapsible-content">		<div class="mw-collapsible-content">

	==Microscopic Description:==		==Microscopic Description==
	===Light Microscopy~~:===~~		===Light Microscopy===
			The specimen consists of a large fragment of renal cortex that contains 60 to 70 glomeruli per level. About 10% of these are obsolete. The remaining glomeruli are generally hypercellular, although the cellularity appears to be inflammatory cells distending the capillary loops rather than mesangial or endothelial cell proliferation. The PASH stain shows thickened basement membrane and focal splitting. Some of the glomeruli are severely atrophic with markedly thickened and wrinkled basement membranes. A few of the glomeruli are globally necrotic. There is diffuse marked interstitial fibrosis with marked tubular atrophy. There are also a number of large collections of mononuclear inflammatory cells throughout the biopsy and numerous examples of tubulitis are identified. The most severely involved tubules contain six to eight lymphocytes per tubular cross section. There are patchy interstitial hemorrhages throughout the biopsy. The vessels generally show obliterative endarteritis, although a few still have a small lumen. Several of the vessels also demonstrate intimal arteritis. Focal necrosis is noted in some of the vessel walls.
	~~===Immunofluorescence:===~~


	~~===Electron Microscopy:~~===


	</div></div>		</div></div>

	<spoiler text="Diagnosis and Comments">		<spoiler text="Diagnosis and Comments">
			Kidney, wedge biopsy - Severe acute interstitial and vascular rejection, Banff grade III.
			- Severe chronic rejection.

			These findings are most consistent with severe acute and chronic rejection. This degree of acute interstitial and vascular rejection corresponds to grade III in the Banff classification.

	</spoiler>		</spoiler>

Peter Anderson: Created page with "'''CRP-31''' ==Clinical History== ==Gross Description:== ==Pathology== ===Case CRP-031 H&E=== specialcrp/CRP-031_HE ===Case CRP-031 PASH=== specialcrp/CRP-031_PASH
Microscopic Description, Immunofluorescence, and Electron Microscopy.

==M..."

2026-10-07T17:57:07Z

Created page with "'''CRP-31''' ==Clinical History== ==Gross Description:== ==Pathology== ===Case CRP-031 H&E=== <peir-vm>specialcrp/CRP-031_HE</peir-vm> ===Case CRP-031 PASH=== <peir-vm>specialcrp/CRP-031_PASH</peir-vm> <div class="usermessage mw-customtoggle-diagnosis" style="cursor:pointer"> Microscopic Description, Immunofluorescence, and Electron Microscopy.</div> <div class="mw-collapsible mw-collapsed" id="mw-customcollapsible-diagnosis"> <div class="mw-collapsible-content"> ==M..."

New page

'''CRP-31'''
==Clinical History==

==Gross Description:==

==Pathology==
===Case CRP-031 H&E===
<peir-vm>specialcrp/CRP-031_HE</peir-vm>
===Case CRP-031 PASH===
<peir-vm>specialcrp/CRP-031_PASH</peir-vm>

<div class="usermessage mw-customtoggle-diagnosis" style="cursor:pointer"> Microscopic Description, Immunofluorescence, and Electron Microscopy.</div>
<div class="mw-collapsible mw-collapsed" id="mw-customcollapsible-diagnosis">
<div class="mw-collapsible-content">

==Microscopic Description:==
===Light Microscopy:===

===Immunofluorescence:===

===Electron Microscopy:===

</div></div>

<spoiler text="Diagnosis and Comments">

</spoiler>

CRP-31 - Revision history

Peter Anderson at 14:32, 8 October 2026

Peter Anderson at 12:58, 8 October 2026

Peter Anderson: Created page with "'''CRP-31''' ==Clinical History== ==Gross Description:== ==Pathology== ===Case CRP-031 H&E=== specialcrp/CRP-031_HE ===Case CRP-031 PASH=== specialcrp/CRP-031_PASH Microscopic Description, Immunofluorescence, and Electron Microscopy. ==M..."

Peter Anderson: Created page with "'''CRP-31''' ==Clinical History== ==Gross Description:== ==Pathology== ===Case CRP-031 H&E=== specialcrp/CRP-031_HE ===Case CRP-031 PASH=== specialcrp/CRP-031_PASH
Microscopic Description, Immunofluorescence, and Electron Microscopy.

==M..."