Difference between revisions of "IPLab:Lab 7:Malignant Melanoma"

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File:IPLab7Melanoma8.jpg|This is a high-power photomicrograph of the main tumor mass showing the cellular details. The individual melanoma cells contain large nuclei with irregular contours having chromatin clumped at the periphery of the nuclear membrane and prominent red (eosinophilic) nucleoli.  
 
File:IPLab7Melanoma8.jpg|This is a high-power photomicrograph of the main tumor mass showing the cellular details. The individual melanoma cells contain large nuclei with irregular contours having chromatin clumped at the periphery of the nuclear membrane and prominent red (eosinophilic) nucleoli.  
 
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== Virtual Microscopy ==
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<peir-vm>IPLab7Melanoma</peir-vm>
  
 
== Study Question ==
 
== Study Question ==
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=== Journal Articles ===
 
=== Journal Articles ===
 
* Banerjee SS, Harris M.  [http://www.ncbi.nlm.nih.gov/pubmed/10792480 Morphological and immunophenotypic variations in malignant melanoma].  ''Histopathology'' 2000 May;36(5):387-402.
 
* Banerjee SS, Harris M.  [http://www.ncbi.nlm.nih.gov/pubmed/10792480 Morphological and immunophenotypic variations in malignant melanoma].  ''Histopathology'' 2000 May;36(5):387-402.
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* Shain AH, Yeh I, Kovalyshyn I, Sriharan A, Talevich E, Gagnon A, Dummer R, North J, Pincus L, Ruben B, Rickaby W, D’Arrigo C, Robson A, and Bastian BC.[http://www.nejm.org/doi/pdf/10.1056/NEJMoa1502583 The Genetic Evolution of Melanoma from Precursor Lesions].  ''New England Journal of Medicine'' 2015 Nov;373:1926-1936.
  
 
=== Images ===
 
=== Images ===
* [http://peir.path.uab.edu/library/index.php?/tags/2148-melanoma PEIR Digital Library: Melanoma Images]
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* [{{SERVER}}/library/index.php?/tags/2148-melanoma PEIR Digital Library: Melanoma Images]
 
* [http://library.med.utah.edu/WebPath/NEOHTML/NEOPLIDX.html WebPath: Neoplasia]
 
* [http://library.med.utah.edu/WebPath/NEOHTML/NEOPLIDX.html WebPath: Neoplasia]
 
== Related IPLab Cases ==
 
 
  
 
{{IPLab 7}}
 
{{IPLab 7}}
  
 
[[Category: IPLab:Lab 7]]
 
[[Category: IPLab:Lab 7]]

Latest revision as of 08:18, 12 November 2015

Contents

Clinical Summary

This 68-year-old white male had a local excision of a pigmented lesion (melanoma) on the skin of his back. Three years later he became aware of a "lump" in his left axilla. Examination confirmed the presence of a 2.3-cm nodularNodular hyperplasia of the prostate--characterized by large discrete prostatic nodules--is a common disorder in men over 50 years of age. The nodules cause the prostate to be enlarged and to have an increased weight. The human prostate is surrounded by a restrictive capsule. These nodules cause increased pressure within the capsule which leads to constriction of the urethra as it passes through the prostate. Urethral constriction leads to retention of urine. lesion. Subsequently, the patient underwent a surgical procedure for removal of axillary lymph nodes.

Images

Virtual Microscopy

Study Question


Additional Resources

Reference

Journal Articles

Images