IPLab:Lab 4:Mural Thrombus

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Clinical Summary

This 67-year-old female was transferred to the hospital from a nursing home in a comatose state. Physical findings on examination were compatible with brain stem infarction. On the fourth hospital day, an electrocardiogram revealed changes compatible with anterior myocardial infarctionMyocardial infarction is necrosis of myocardial tissue which occurs as a result of a deprivation of blood supply, and thus oxygen, to the heart tissue. Blockage of blood supply to the myocardium is caused by occlusion of a coronary artery.. The patient remained comatose with quadriplegia and expired on the 16th hospital day.

Autopsy Findings

Examination of the brain revealed extensive infarction involving the midbrain and cerebellum with complete occlusionAn occlusion is a blockage. of the upper one-half of the basilar artery; there was also extensive coronary artery atherosclerosis. A large aneurysm of the left ventricle was present; this was filled with mural thrombusMural thrombosis is the formation of multiple thrombi along an injured endocardial wall.. Extensive infarction of the lateral and posterior portions of the left ventricular wall toward the base of the heart was also found.


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