Difference between revisions of "IPLab:Lab 1:Fat Necrosis"

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(Journal Articles)
(Journal Articles)
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=== Journal Articles ===
=== Journal Articles ===
* Bhatnagar A, Wig J, Vaiphei K, Majumdar S. [http://www.ncbi.nlm.nih.gov/pubmed/11560386 Intracellular cytokines in cells of necrotic tissue from patients with acute pancreatitis].  ''Eur J Surg'' 2001 Jul;167(7):510-7.
* Forsmark CE, Vege SS, Wilcox CM. [http://www.nejm.org/doi/full/10.1056/NEJMra1505202 Acute Pericarditis].  ''N Engl J Med" 2016; 375:1972-1981. November 17, 2016.
* LeWinter MM. [http://http://www.nejm.org/doi/full/10.1056/NEJMcp1404070 Acute Pericarditis].  ''NEJM'' 2014 Dec 18;371:2410-2416.
* LeWinter MM. [http://http://www.nejm.org/doi/full/10.1056/NEJMcp1404070 Acute Pericarditis].  ''NEJM'' 2014 Dec 18;371:2410-2416.

Latest revision as of 12:30, 21 November 2016


Clinical Summary

This was a 37-year-old female with chronic renal failureRenal failure is the severe reduction of renal function and often leads to reduced urinary output. that necessitated a renal transplant. Following transplantation, the patient developed a herpes simplex virus (HSV) infection in her nasal cavity, oral candidiasisCandidiasis is an infection by the fungus Candida in the oral cavity., pneumoniaIn alcoholics, aspiration pneumonia is common--bacteria enter the lung via aspiration of gastric contents., hematuriaHematuria is the presence of blood in the urine., pyuriaPyuria is the presence of white blood cells (pus) in the urine., and gastrointestinal bleeding. Subsequently, the patient became septicSepsis is the presence and persistence of pathogenic microorganisms and their toxins in the blood. and died.

Autopsy Findings

Major findings at autopsy included extensive hemorrhagic bronchopneumonia (Pseudomonas aeruginosa) and multiple ulcers affecting the stomach and esophagus. There was also evidence of disseminated intravascular coagulationDIC is the development of small thrombi within the microcirculation throughout the body. (DIC) with multiple hemorrhages present. Firm, whitish foci of necrotic tissue were found in the fat around the pancreas.


Virtual Microscopy

Pancreatic Fat Necrosis

Normal Pancreas

Study Questions

Additional Resources


Journal Articles