Difference between revisions of "IPLab:Lab 11:Chagas Disease"

From Pathology Education Instructional Resource
Jump to: navigation, search
(Journal Articles)
 
Line 29: Line 29:
 
* Bestetti RB.  [http://www.ncbi.nlm.nih.gov/pubmed/11422962 Predictors of unfavourable prognosis in chronic Chagas' disease].  ''Trop Med Int Health'' 2001 Jun;6(6):476-83.
 
* Bestetti RB.  [http://www.ncbi.nlm.nih.gov/pubmed/11422962 Predictors of unfavourable prognosis in chronic Chagas' disease].  ''Trop Med Int Health'' 2001 Jun;6(6):476-83.
 
* Calzada JE, Nieto A, Beraún Y, Martín J.  [http://www.ncbi.nlm.nih.gov/pubmed/11703822 Chemokine receptor CCR5 polymorphisms and Chagas' disease cardiomyopathy].  ''Tissue Antigens'' 2001 Sep;58(3):154-8.
 
* Calzada JE, Nieto A, Beraún Y, Martín J.  [http://www.ncbi.nlm.nih.gov/pubmed/11703822 Chemokine receptor CCR5 polymorphisms and Chagas' disease cardiomyopathy].  ''Tissue Antigens'' 2001 Sep;58(3):154-8.
 +
* Bern C.  [http://www.nejm.org/doi/full/10.1056/NEJMra1410150 Chagas’ Disease].  ''NEJM'' 2015 July 30;373:456-466.
  
 
=== Images ===
 
=== Images ===

Latest revision as of 08:31, 25 August 2016

Contents

Clinical Summary

This 12-year-old boy, whose family had recently emigrated from Brazil, presented to the emergency room with a three-day history of malaise, fever, anorexia, and edema of the face and upper extremities. On physical examination the patient had generalized lymphadenopathy and hepatosplenomegaly. The patient was tachycardic and dysgenic with signs of congestive heart failure. A cardiac biopsy was performed which revealed an active myocarditis with leishmanial forms of parasitic organisms within cardiac myocytes. Close examination of peripheral blood smears revealed occasional circulating trypomastigotes. A complement fixation test for antibodies to Trypanosoma cruzi was strongly positive.

Images

Virtual Microscopy

Study Questions


Additional Resources

Reference

Journal Articles

Images