Cytologically Yours: CoW: 20140106
64 year old male who presented to the ED with shortness of breath.
Past Medical History
- Recent diagnosis of metastatic melanoma of unknown primary
Past Surgical History
- Metastatic melanoma of unknown primary diagnosed in an enlarged axillary mass that was removed several months previously.
- CXR and CT showed multiple pulmonary nodules and bilateral pleural effusions.
- Metastatic melanoma.
Melanoma is "the great mimicer", it's cytomorphology can be very variable. Prominent nucleoli and pigment are some of the features that can help guide a pathologist to the diagnosis. The use of the immunohistochemical markers MART-1, S100, MITF,and MelanA are useful for the diagnosis of melanoma.