IPLab:Lab 8:Poliomyelitis

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Clinical Summary

Six days before his death, this 31-year-old white male became acutely ill with fever followed by an ascending paralysis which began in his feet. Three days later he was hospitalized because of difficulty in breathing. A lumbar puncture was performed and the patient's spinal fluid contained increased protein and polymorphonuclear leukocytes (4.30 PMNs/mm³Normally, there should be no PMNs in a patient's spinal fluid.). He died on the third hospital day.

Autopsy Findings

At autopsy, the thoracic and lumbar portions of the spinal cord were softer than normal and focally hemorrhagic.


Virtual Microscopy


Normal Spinal Cord

Study Questions

Additional Resources


Journal Articles