IPLab:Lab 6:Glomerulonephritis

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Clinical Summary

This 17-year-old white male had end-stage renal disease requiring hemodialysis for 10 years. For the previous four years he had hypertension which slowly increased to about 180/120A normal alkaline phosphatase is 39 to 117 U/L. mm Hg. Laboratory findings included a greatly elevated BUN and creatinineThese tests are measures of kidney function. High levels mean low function.. He was admitted for bilateral nephrectomy and discharged in satisfactory condition on the 10th postoperative day. He was to be contacted in the future for transplantation.

Autopsy Findings

The left (97 gramsA normal kidney weighs 157 grams (range: 115 to 220 grams).) and right (88 gramsA normal kidney weighs 157 grams (range: 115 to 220 grams).) kidneys were of similar appearance. Cortices were pale, diffusely granular with a few 1-2 mm cysts. On being sectioned, the cortex of each kidney was thin (4-5 mm) and pale. Renal medullae were pale yellow-tan in color and there was abundant peripelvic fat. The ureters, pelvis, calyces and hilar vessels showed no abnormalities.


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