IPLab:Lab 2:Metastatic Calcification

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Clinical Summary

This 47-year-old woman diagnosed with metastatic carcinoma of the breast was also found to have severe hypercalcemiaHypercalcemia is the state of having increased levels of calcium in the blood.. She developed metastatic calcificationThe deposition of calcium in normal tissues as a result of elevations in blood calcium. which was most prominent in the kidneys and lungs.

Autopsy Findings

In addition to the metastatic breast cancer, important gross findings at autopsy included lungs that were gritty and firm and which weighed 1330 gramsA normal pair of lungs weighs 825 grams (range: 685 to 1050 grams).. The patient's parathyroid glands were normal (two parathyroid hormone assays during life were normal).


Virtual Microscopy

Lung: Metastatic Calcification

Normal Lung

Study Questions

Additional Resources


Journal Articles