From UAB Pathology Undergraduate Education Web site (http://peir.path.uab.edu/pathgrad)
Program for Research Experience in Pathology: Program for Research Experience in Pathology
What is the PREP Program?
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Some of the most challenging areas for today's college graduates are in the field of modern biomedical sciences. Environmental pollution, new infectious diseases, and the continuing human health problems of cancer, heart disease, diabetes, neurological disorders and inherited genetic diseases are more prominent today than at perhaps any other time in history. At the same time, today's biomedical scientist is equipped with some of the most powerful tools and technologies for understanding basic disease mechanisms. Ultimately, the proper use of these new tools and technologies will provide insights into potential remedies for these diseases.
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At the forefront of the biomedical sciences is the relatively new field of molecular pathology. Scientists trained in molecular and cellular pathology use the tools of molecular biology, biochemistry and cell biology to probe into the processes which underlie human diseases. |
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The UAB Department of Pathology and The Graduate Program in Molecular and Cellular Pathology are pleased to offer to qualified college-level science majors an undergraduate research program in molecular and cellular pathology. This program is designed to introduce students to this exciting and challenging field of modern experimental pathology.
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PREP Curriculum
Students will become an integral part of an investigative team and will spend approximately 10 weeks during the summer months working in the laboratories of scientists in the Department of Pathology at the University of Alabama Medical Center on projects related to the molecular basis of disease.
Investigators with research programs in such diverse areas as cardiovascular disease, carcinogenesis, metabolic disorders, immunobiology, and signal transduction will participate in the undergraduate training program.
Students will receive first-hand laboratory experience participating in and conducting experiments with the faculty and other laboratory personnel. A weekly conference series with faculty and other students in the program will also be held allowing students the opportunity to learn the scientific principles underlying research in molecular and cellular pathology.
The goal of the program is to introduce students to the nature of scientific research, and to foster an appreciation for experimental approaches used to understand disease processes.
Application and Admission Process
Applications from interested students will be evaluated on the basis of grades, courses taken, a statement of interest in pursuing graduate education, and recommendations from faculty members at the student's institution.
Evaluations of complete applications received in the office of the Graduate Program in Molecular and Cellular Pathology, will commence on March 16 and will continue until all openings are filled. Thus, to ensure the best chance for acceptance into the program it is recommended that completed applications be received by March 15, 2009.
After a screening process, successful applicants will be invited to participate in the program and will be assigned a summer project with a member of the graduate faculty in the Molecular and Cellular Pathology Graduate Program, based on the student's statement of interests. Successful applicants will be notified by March 31, 2009.
Students invited to participate in the PREP will receive a stipend for the 10-week program of $3,000 plus free housing. At the end of the summer research program, students will discuss the results of their work in the form of poster presentations. The poster session will be followed by a faculty-student reception given in honor of the summer undergraduate research participants. All of the undergraduate participants will be encouraged to apply to graduate programs in the biomedical sciences at UAB including the Graduate Program in Molecular and Cellular Pathology.
Apply to PREP
Please mail completed PREP applications to the following address:
University of Alabama at Birmingham
Department of Pathology
Division of Molecular and Cellular Pathology c/o MCP PREP Program
Volker Hall, G019
1530 3rd Avenue South
Birmingham, Alabama 35294
PREP Student Projects
The summer of 1995 was the inaugural year for the Program for Research Experience in Pathology (PREP). Nine students representing colleges and universities from around the United States were engaged in original research in the laboratories of the mentors of the PREP program.
Listed below are past PREP students and their projects. The success of the program in previous years assures an equally successful program for all students selected each year.
PREP Faculty and Research Programs
Listed below are some of the participating faculty in the PREP program and their research projects for summer students. Students expressing an interest in one or more of these research projects will be put in contact with the appropriate faculty member upon acceptance into the PREP.
For further information, visit the UAB Department of Pathology Web site at http://www.path.uab.edu/.
- Dr. Scott Ballinger: Molecular cardiology. Effects of environmental factors on cardiovascular oxidant load, function, and damage.
- Dr. William H. Benjamin, Jr.: Bacterial genetics. Role of specific genes in Salmonella resistance in mouse and human diseases.
- Dr. Pat Bucy: Immunology and transplant rejection.
- Dr. Steven Carroll: Molecular events responsible for axonal regeneration in the injured mannalian nervous system.
- Dr. Xu Cao: Osteoblast differentiation.
- Dr. Victor Darley-Usmar: Biochemistry of free radicals. Mechanisms of free radical injury in cardiovascular disease.
- Dr. Joanne Douglas: The development of adenoviruses as vectors for gene therapy and the mechanisms by which the adenovirus interacts with cellular receptors during the process of infection
- Dr. Xu Feng: Molecular mechanisms controlling the formation and function of osteoclasts. The intracellular signaling pathways involved in osteoclast formation and function and treating diseases such as osteoporosis and rheumatoid arthritis.
- Dr. Andra Frost: Biomarkers in breast cancer.
- Dr. Candece Gladson: The molecular mechanisms involved in malignant glial cell adhesion and invasion.
- Dr. Robert W. Hardy: Metabolic regulation. Role of fatty acids in the modulation of glucose transport and calcium homeostasis in normal and cancer cells.
- Dr. Dennis Kucik: Single particle tracking and manipulation of microscopic objects with laser tweezers to detect how cells perform and regulate these functions.
- Dr. Robin Lorenz: Mucosal immunology. The role of the immune system in regulating gastrointestinal diseases such as gastric and intestinal infections, autoimmune diseases and cancer.
- Dr. Upender Manne: Mutational analysis of the p53 gene in adenomas and adenocarcinomas of the colorectum.
- Dr. Jay McDonald: Biochemistry of signal transduction. Regulation of apoptosis by calcium signaling in cells.
- Dr. Joseph L. Messina: Molecular endocrinology. Role of hormones, growth factors, and signaling pathways in the regulation of gene expression, diabetes, and cancer.
- Dr. Joanne E. Murphy-Ullrich: Cell biology of the extracellular matrix. Mechanisms of extracellular matrix protein signaling in cultured endothelial cells.
- Dr. Rakesh Patel: Nitric oxide, heme proteins, blood substitutes, free radicals and cell signaling.
- Dr. Selvarangan Ponnazhagan: Adeno-associated virus (AAV)-mediated gene therapy. Improving the characteristics of the vector for efficient and cell-specific targeting.
- Dr. Kevin Roth: Neuronal apoptosis in development and neurodegenerative diseases.
- Dr. Casey Weaver: Costimulatory molecules, T-cell receptor signaling.
- Dr. Dan Welch: Biology, genetics and biochemistry of cancer metastasis (spread).
- Dr. Majd Zayzafoon: Cancer biology and bone development. The role of calcium signaling in the genetic pathogenesis of diseases such as prostate cancer, bone metastases, osteoporosis, and inflammatory bowel disease
Contact PREP
PREP Office Phone: (205) 934-2445
PREP Office Fax: (205) 975-1126
PREP Chair: Dr. Selvarangan Ponnazhagan
PREP Administrative Contact: Nicole Newton
Volker Hall G019
Phone: 934-2445
Fax: 975-1126
Email: nicolen@uab.edu
© Copyright by the University of Alabama at Birmingham