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John Wang Mail Email this article  
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Previous | Molecular & Cellular Pathology Graduate Student Profiles | Next

I am interested in converting basic science knowledge to real therapeutic applications that can be helpful to patients, and that is the reason that I joined the MD/PhD program here at the Univeristy of Alabama at Birmingham. My current research interest involves study into the regulation of activation-induced deaminase (AID) by type I IFN and plasmacytoid dendritic cells in the BXD2 autoimmune mouse model. AID is an RNA-editing enzyme critical to antibody isotype class-switch and somatic hypermutation, two processes essential to generating high-affinity IgG isotype antibodies. By better understanding the regulation of this critical enzyme, we hope to further understand the role of AID and type I IFN in autoimmune disease development.

In my free time, I like to read and write.






   Hometown:

Arcadia, California



Undergraduate/Masters Institution:

Chemistry, B.S., Economics, A.B.
University of California at Berkeley



General Research Interests:

Type I IFN, plasmacytoid dendritic cells, and autoimmune disease




 

 


Previous | Molecular & Cellular Pathology Graduate Student Profiles | Next




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