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My research has taken new directions through collaborations with
investigators all across campus. I feel certain my training here will provide me
with a solid foundation
for my future endeavors. |
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Hometown:
Moody, AL
Undergraduate/Masters
Institution:
University of Alabama at
Birmingham
General Research Interests:
Free
Radical/Vascular Biology
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Nitric oxide (NO) is a free
radical and a central mediator in vascular homeostasis. In the vasculature NO is
metabolized via interactions with heme proteins or by oxidation reactions to
nitrite and ultimately nitrate. These reactions were long thought to terminate
the biological activity of NO. However, current data suggest that during states
of hypoxia nitrite serves as a pool of
NO. |
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My research is focused on elucidating mechanisms by which red blood cells,
specifically hemoglobin, reduce nitrite to NO during physiological and
pathological states of hypoxia. |
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