KARYOTYPE: HEMATOLOGIC: BONE MARROW: Philadelphia chromosome in Chronic Myelogenous Leukemia (CML); Ph, t(9;22) results in a fusion mRNA of 210 kd called bcr/abl which inhibits cellular apoptosis and increase granulocytes in Chronic Myelogenous Leukemia (CML). Besa/Peter C. Nowell, M.D. Karyotype Slides