From UAB Coagulation Service (http://coag.path.uab.edu)
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Factor IX Activity Assay
| Primary Name |
Factor IX Assay |
| Synonym |
Factor IX Functional Assay |
| Synonym |
-- |
| Contraction |
FIX |
| Contraction |
-- |
| Contraction |
-- |
| UAB Procedure Number |
2500500 |
| CPT Code |
85250 |
| Specimen |
Collect one (1) blue-stopper tube (3.2% sodium citrate), filled to specified volume. Do not underfill or overfill. |
| Specimen Management |
Note time of collection and time of last treatment if applicable. Centrifuge blue-stopper tube within 1 hour of collection, separate plasma and test or quick-freeze at -70°C. |
| Specimen Accepted |
Daily including weekends |
| Times Available |
0730-1600; deliver to lab by 1300 for same-day results |
| Test Performed |
Monday-Friday. |
| Available Stat? |
Pathologist's approval required. |
| Description |
Congenital factor IX deficiency, termed hemophilia B, is inherited as a sex-linked recessive and is seen in 1 in 30,000 males. Acquired factor IX deficiency is seen in liver disease, vitamin K deficiency, and Coumadin therapy. Factor IX deficiency is associated with mild to severe bleeding. |
| Reference Interval |
50-150% |
| Critical Value |
-- |
| Therapeutic Range |
-- |
| Follow-up Test |
If an anti-IX inhibitor is suspected, the anti-IX inhibitor titer (Bethesda titer) may be ordered. |
| Associated With |
Bleeding disorders |
| Associated With |
Vitamin K deficiency |
| Associated With |
Liver disease |
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