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| Primary Name |
Factor IX Inhibitor Titer |
| Synonym |
Bethesda Titer for Factor IX Inhibitor |
| Synonym |
-- |
| Contraction |
FIX Inhibitor |
| Contraction |
FIX Inh |
| Contraction |
-- |
| UAB Procedure Number |
2500510 |
| CPT Code |
85730, 85732, 85250, 85335 |
| Specimen |
Collect one (1) blue-stopper tube (3.2% sodium citrate), filled to specified volume. Do not underfill or overfill. |
| Specimen Management |
Centrifuge blue-stopper tube within 1 hour of collection, separate plasma and test or quick-freeze at -70°C. |
| Specimen Accepted |
Daily including weekends |
| Times Available |
0730-1600; deliver to lab by 1300 for same-day results |
| Test Performed |
Monday-Friday. |
| Available Stat? |
Pathologist's approval required. |
| Description |
Factor IX inhibitors are IgG alloantibodies specific for therapeutic factor IX. Factor IX inhibitors appear in 1 to 6% of severe hemophilia B patients. Inhibitors typically neutralize therapeutic factor IX concentrates making it necessary to provide patients with alternative therapy. |
| Reference Interval |
None detected |
| Critical Value |
-- |
| Therapeutic Range |
-- |
| Follow-up Test |
-- |
| Associated With |
Bleeding disorders |
| Associated With |
Coagulation factor inhibitors |
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