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| Primary Name |
Factor II Assay |
| Synonym |
Prothrombin Assay |
| Synonym |
Factor II Functional Assay |
| Contraction |
FII |
| Contraction |
-- |
| Contraction |
-- |
| UAB Procedure Number |
2500470 |
| CPT Code |
85210 |
| Specimen |
Collect one (1) blue-stopper tube (3.2% sodium citrate), filled to specified volume. Do not underfill or overfill. |
| Specimen Management |
Note time of collection and time of last treatment if applicable. Centrifuge blue-stopper tube within 1 hour of collection, separate plasma and test or quick-freeze at -70°C. |
| Specimen Accepted |
Daily including weekends |
| Times Available |
0730-1600; deliver to lab by 1300 for same-day results |
| Test Performed |
Monday-Friday. |
| Available Stat? |
Pathologist's approval required. |
| Description |
Congenital factor II (prothrombin) deficiency is caused by one of several rare mutations that reduce prothrombin production or activity. Acquired prothrombin deficiency is caused by vitamin K deficiency, the use of Coumadin therapy, or prothrombin-neutralizing lupus anticoagulant. |
| Reference Interval |
50-150% |
| Critical Value |
-- |
| Therapeutic Range |
-- |
| Follow-up Test |
If the functional prothrombin assay indicates a deficiency, the prothrombin antigen assay may be used to distinguish qualitative from quantitative disorders. |
| Associated With |
Bleeding disorders |
| Associated With |
Lupus anticoagulant |
| Associated With |
Vitamin K deficiency |
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