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| Primary Name |
Ristocetin Response Curve |
| Synonym |
Low-dose ristocetin-induced platelet aggregation |
| Synonym |
Low-dose ristocetin-induced platelet agglutination |
| Contraction |
Low-dose RIPA |
| Contraction |
-- |
| Contraction |
-- |
| UAB Procedure Number |
2500352 |
| CPT Code |
85307 |
| Specimen |
Collect nine (9) 2.7 mL or six (6) 4.5 mL blue-stopper tubes (3.2% sodium citrate), filled to specified volume. Do not underfill or overfill. |
| Specimen Management |
Do not centrifuge. Maintain tubes at room temperature and deliver to special coagulation laboratory within 3 hours of collection. |
| Specimen Accepted |
Monday-Friday |
| Times Available |
0730-1600; deliver to lab by 1300 for same-day results |
| Test Performed |
Monday-Friday |
| Available Stat? |
Pathologist approval required. |
| Description |
The ristocetin response curve is used to identify von Willebrand disease type 2B. This is a rare "gain of function" form of von Willebrand disease in which von Willebrand factor binds platelets excessively. The platelet count is usually reduced in von Willebrand disease type 2B. |
| Reference Interval |
The results are interpreted by a pathologist. |
| Critical Value |
-- |
| Therapeutic Range |
-- |
| Follow-up Test |
Platelet count |
| Associated With |
Bleeding disorders |
| Associated With |
Von Willebrand disease |
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